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Diabetes drugs tied to pancreatitis, study finds

Posted: Published on March 1st, 2013

People who take a certain type of diabetes drug to lower blood sugar levels may be at an increased risk of developing an inflamed pancreas, according to a new study. Glucagonlike peptide 1(GLP-1) therapies that include exenatide - marketed as Byetta by an alliance between Bristol-Myers Squibb and AstraZeneca - and sitagliptin - marketed as Januvia by Merck - have been linked to pancreatitis before in studies on animals and small groups of patients, said the study's lead author. "New therapies and risks are only evaluated when studies are done. We need to know (the drugs) are effective in lowering blood sugar, but we also need to know about risks," said Dr. Sonal Singh, from the Johns Hopkins University School of Medicine in Baltimore. Pancreatitis, which can cause life-threatening complications, is rare but more common in people with type 2 diabetes. Singh said pancreatitis occurs in about three of every 1,000 diabetes patients. The U.S. Centers for Disease Control and Prevention estimates that there are about 19 million Americans diagnosed with diabetes, and another 7 million who have the disease but don't know it yet. In people with type 2 diabetes, the body doesn't produce enough insulin or is resistant … Continue reading

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Diabetes drugs tied to pancreatitis: study

Posted: Published on March 1st, 2013

NEW YORK (Reuters Health) - People who take a certain type of diabetes drug to lower blood sugar levels may be at an increased risk of developing an inflamed pancreas, according to a new study. Glucagonlike peptide 1(GLP-1) therapies that include exenatide - marketed as Byetta by an alliance between Bristol-Myers Squibb and AstraZeneca - and sitagliptin - marketed as Januvia by Merck - have been linked to pancreatitis before in studies on animals and small groups of patients, said the study's lead author. "New therapies and risks are only evaluated when studies are done. We need to know (the drugs) are effective in lowering blood sugar, but we also need to know about risks," said Dr. Sonal Singh, from the Johns Hopkins University School of Medicine in Baltimore. Pancreatitis, which can cause life-threatening complications, is rare but more common in people with type 2 diabetes. Singh said pancreatitis occurs in about three of every 1,000 diabetes patients. The U.S. Centers for Disease Control and Prevention estimates that there are about 19 million Americans diagnosed with diabetes, and another 7 million who have the disease but don't know it yet. In people with type 2 diabetes, the body doesn't produce … Continue reading

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After Successful Pilot, London Drugs Brings PreVu(R) Skin Cholesterol Testing Into Pharmacy Clinical Services Across …

Posted: Published on March 1st, 2013

RICHMOND, BRITISH COLUMBIA--(Marketwire - Feb 28, 2013) - London Drugs is proud to be the first in Canada to offer our patients and customers a non-invasive preview into their cholesterol history and health through PreVu - a simple skin cholesterol test. The PreVu test measures the cholesterol found on the bodies'' largest organ, the skin, where cholesterol is accumulated with age. The test is conducted on the palm of the hand in less than five minutes, involves no blood draw, needles or fasting with results available immediately. "We have reviewed the clinical research using this screening technology and have listened to our pharmacists and customers about whether this test would assist in one''s overall health management," said John Tse, London Drugs vice president, pharmacy. "What we learned is that PreVu can assist to either put a patient''s mind at ease if they score low on the skin cholesterol scale or if scoring high, the patient needs to see their doctor to have a blood cholesterol test and further risk assessment conducted." While skin cholesterol isn''t the same as blood cholesterol, it provides valuable information when assessing risk of coronary artery disease (CAD) or heart disease. In October 2012, London Drugs … Continue reading

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FDA staff say two non-hormonal hot flashes drugs show some efficacy

Posted: Published on March 1st, 2013

(Reuters) - Food and Drug Administration staff said experimental drugs by Depomed Inc and Hisamitsu Pharmaceutical Co Inc showed efficacy in reducing menopausal hot flashes, and highlighted no new risks in comments issued on Thursday. Depomed's shares rose 8 percent on optimism that its drug, which failed to meet pre-defined efficacy goals in studies, may still be approved to address an estimated $1.5 billion market. Depomed's Sefelsa was effective in reducing the frequency and severity of hot flashes related to menopause after four weeks of treatment in studies, but results varied after 12 weeks of treatment, FDA staff observed in a report posted online on Thursday. (http://r.reuters.com/jyx36t) Japanese drugmaker Hisamitsu's paroxetine mesylate capsules was shown to be more consistent at reducing the incidence of the condition than at reducing the severity of flashes. (http://r.reuters.com/fab46t) Both drugs are vying to become the first approved, non-hormonal drug to treat menopausal hot flashes. Most women going through menopause experience these flashes, a complex set of feelings that start with warmth and redness, accompanied by sweating, palpitations and anxiety that typically lasts several minutes. About 13 million of nearly 32 million women who experience hot flashes during menopause seek treatment in the United States, … Continue reading

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Trio robs Frankford pharmacy at gunpoint

Posted: Published on March 1st, 2013

Action News FRANKFORD - February 28, 2013 (WPVI) -- A trio of robbers targeted a pharmacy and it appears that they were able to use the security guard's own weapon to help them pull it off. At around 7:00 p.m. the three suspects entered the Oxford Circle Pharmacy on East Cheltenham Avenue and Horrocks Street in the Frankford section of Philadelphia. They immediately went to the armed security guard. Investigators say the guard complied and the suspect took his .45 caliber gun and began to rob the place. "They stole about $150 in cash and about 100 bottles of oxycodones and amphetamines," Small said. The bandits then fled the store and jumped in a white vehicle, possibly a Chevrolet Monte Carlo or Impala. Detectives believe the bandits knew an armed guard was inside the store. The entire incident was captured on the store's surveillance system. However, because the suspects were covered from head to toe, police do not have a good description of them. Read more from the original source: Trio robs Frankford pharmacy at gunpoint … Continue reading

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Pharmacy Guild supports Society's recertification programme

Posted: Published on March 1st, 2013

Following member feedback and discussions with the Pharmaceutical Society (the Society), the Pharmacy Guild of New Zealand (the Guild) will not progress with the development of its own Continuing Professional Development (CPD) recertification programme at this time and instead, is endorsing the programme, ENHANCE 2.0, being developed by the Society. The Guild is committed to ensuring that a quality CPD recertification programme is available to its members, recognising that the platform for such a programme must meet the needs of todays pharmacists. Guild Board members have reviewed the programme offered by the Society and believe that it addresses the historical concerns members had with the programme under the previous framework. "This decision follows feedback from members and the Boards consideration of the detailed business case for the development of the Guilds own CPD recertification programme. The Board believes that the development of a duplicate programme is not the best use of Guild member funds given the quality of the programme being developed by the Society", said Guild President, Karen Crisp. "We believe that member funds would be better spent in support of our PSA work and other advocacy activities," she added. Ms Crisp explained that the Guild and the Society … Continue reading

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Treating Duchenne, the most common of the rare diseases

Posted: Published on March 1st, 2013

With an incidence of 1 out of 3,500 male births, Duchenne muscular dystrophy is one of the most common of the orphan or rare diseases. But, the effects of the disease, which causes death by the average age of 25, are some of the most destructive according to experts. Orphan or rare diseases are defined in the United States as an illness that affects fewer than 200,000 people throughout the country. Duchenne is a subset of muscular dystrophy that occurs when a person has a genetic defect in which they cannot produce a protein that is present in muscle tissue, called dystrophin. It has the same worldwide incidence as it does in the United States, and may even have the same proportion of cases in the animal kingdom as well. 16 Photos Duchenne's patients are diagnosed around 3 or 4 years old, and normally don't show symptoms before they start exhibiting muscle weakness and are unable to keep up with their peers. "It's pretty devastating," Eric Hoffman, the director of the Center for Genetic Medicine Research at Children's National Medical Center, said to CBSNews.com. "These boys are born normally, and don't show weakness until early school age. We just do … Continue reading

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Help Corpus Christi firefighters battle muscular dystrophy with Fill the Boot donation

Posted: Published on March 1st, 2013

CORPUS CHRISTI Corpus Christi firefighters will team up to help raise money for the Muscular Dystrophy Association as part of its annual Fill the Boot campaign. The firefighters will be at intersections across the city for the next three Fridays, asking motorists for donations. Every dollar helps the Local No. 936 firefighters group provide medical treatment and support services to individuals and their families living with neuromuscular diseases in the Corpus Christi area, according to a news release. The International Association of Firefighters has been a national MDA partner for more than 50 years. We know the money we raise definitely makes a difference in the lives of people affected by neuromuscular diseases, and that it helps them get the care they need, said Carlos Torres local chapter president. Fill the Boot is a proud tradition for us, and its a great way for firefighters to be out in the community reminding residents that we are here, always ready to help. Some of the intersections firefighters will be stationed at each Friday are: Holly and Airline roads; Weber and Saratoga roads; and Leopard Street and Navigation Boulevard. See original here: Help Corpus Christi firefighters battle muscular dystrophy with Fill the … Continue reading

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Parent Project Muscular Dystrophy Marks Rare Disease Day with Multiple Awareness Events

Posted: Published on March 1st, 2013

HACKENSACK, N.J., Feb. 28, 2013 /PRNewswire-USNewswire/ -- Parent Project Muscular Dystrophy (PPMD), the leading non-profit in the United States focused entirely on Duchenne muscular dystrophy (Duchenne), will mark the six year anniversary of Rare Disease Day today by participating in two important events that will raise awareness about Duchenne and share with audiences compelling stories from our community. (Logo: http://photos.prnewswire.com/prnh/20100119/DC39975LOGO) PPMD Founder, President, and CEO Pat Furlong will participate in the 3rd Annual Sanford Rare Disease Symposium in Sioux Falls, South Dakota. In commemoration of the 30 million Americans affected by nearly 7,000 rare diseases, Sanford Research will be hosting its symposium to increase public awareness of rare diseases and provide information to healthcare providers and researchers. Pat will share her Duchenne journey, as well as discuss the role PPMD continues to play in advancing research, advocating in Washington, and improving care. PPMD's Chief Operating Officer, Kimberly Galberaith will be simultaneously participating in a Rare Disease Day Town Hall Meeting hosted by Pfizer. Duchenne was one of only a couple of rare diseases focused on in this meeting, and PPMD is honored to be putting together a panel of families to tell their stories. Says Ms. Galberaith, "The importance of … Continue reading

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FDA will review Stedesa, Sunovion’s epilepsy drug candidate

Posted: Published on March 1st, 2013

By Chris Reidy, Globe Staff Marlborough drug maker Sunovion Pharmaceuticals Inc. said that US regulators have agreed to review its application to market a potential new treatment for the most common form of epilepsy. The drug candidate is called Stedesa, the proposed trade name for eslicarbazepine acetate, and if approved, it could offer US adults with epilepsy a way to manage partial onset seizures, Sunovion senior vice president Fred Grossman said in a statement included in the companys press release. The company first submitted an application for eslicarbazepine acetate to the US Food and Drug Administration in 2009. The company was still known as Sepracor Inc. then. That same year Sepracor was acquired by the Japanese drug maker Dainippon Sumitomo Pharma Co. Ltd., or DSP, for $2.6 billion. In 2010, DSP changed Sepracors name to Sunovion. In 2010, the FDA asked the company to provide it with additional information about eslicarbazepine acetate, and Sunovion said in a Wednesday press release that it has been informed by the FDA that the agency has sufficient data to review Sunovions drug application. Sunovion said it expects the FDA to make a decision about Stedesa/eslicarbazepine acetate later this year. Eslicarbazepine acetate won approval from … Continue reading

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