WALTHAM, Mass.--(BUSINESS WIRE)-- Kala Pharmaceuticals, Inc., a leading developer of innovative products that rapidly and effectively penetrate the mucosal barrier to treat a wide range of debilitating diseases, announced today that it has secured $11.5 million in Series A equity financing through new and existing investors. New and lead investor, Crown Venture Fund, LLC, the venture capital arm of the Crown family of Chicago, joined Kalas existing investors, including Lux Capital Management, Polaris Venture Partners and Third Rock Ventures. Proceeds from the financing will be used to advance a portfolio of innovative ophthalmic programs based on Kalas Mucosal Penetrating Product (MPP) platform through clinical proof of concept. "Kala's front of the eye drug delivery advantages and ability to topically deliver a wide variety of drugs to the back of the eye will transform the ophthalmology sector," said Richard Robb, a CVF representative. Crown Venture Fund is pleased to join Kalas existing investors and support this team of ophthalmology industry leaders. With Crown Venture Fund we are pleased to expand our circle of committed, long-term investors who recognize the significant potential of this breakthrough technology, said Guillaume Pfefer, Ph.D., Kalas CEO. This financing provides Kala with the resources to further deploy … Continue reading →

Stroke Recovery Stroke Treatment Using Adult Stem Cells Bryn came to Dr. David Steenblock after suffering from a stroke. After going to numerous facilities he was finally able to get help with his stroke recovery after coming to Dr. David Steenblock. Dr. Steenblock used adult stem cell treatments to help aid Bryn in his stroke recovery. Call 1-800-300-1063 for more information. By: David Steenblock … Continue reading →

Stem Cells: Molly at 31 days 31 days after getting her Stem cells treatment. By: GrandPawsAZ … Continue reading →

Post Regenexx Stem Cell Treatment Results for JR's Knee | Rejuv Medical, Minnesota JR Burgess had a sport related knee injury. JR, went to Joel Baumgartner, MD to under go the stem cell injections for regenerative growth in his knee. Rejuv Medical has been following JR's incredible results and recovery from the stem cell procedure that he has had done at Rejuv Medical of Saint Cloud, MN. http://www.rejuvmedical.com By: Rejuv Medical … Continue reading →

Feb. 27, 2013 In a significant advance for harnessing the immune system to treat leukemias, researchers at Fred Hutchinson Cancer Research Center for the first time have successfully infused large numbers of donor T-cells specific for a key anti-leukemic antigen to prolong survival in high-risk and relapsed leukemia patients after stem cell transplantation. Both the stem cells for transplant and the T-cells came from the same matched donors. Reporting results of a pilot clinical trial in the Feb. 27 issue of the journal Science Translational Medicine, researchers describe the use of T-cells that were taken from a donor, programmed in the lab to recognize the Wilm's Tumor Antigen 1 (WT1) and kill leukemia cells, grown in large numbers, and then infused into patients to promote anti-leukemic activity. The WT1 protein is overexpressed in leukemias and is in part responsible for why the cells have become leukemic. The best results were achieved when some of the patients received T-cell clones that were exposed to interleukin 21 (IL-21) during the programming and growth process, based on the hypothesis that such exposure would create cells that could survive longer and produce greater anti-leukemic activity after transfer. IL-21 promotes T-cell expansion while helping those … Continue reading →

Durham, N.C. People with heart disease have more treatment options than ever. However, sometimes nothing gets rid of continued chest pain known as angina. Researchers say they are looking at a special stem cell therapy to help those patients. Danny Darden, 49, has heart disease and frequent chest pain despite two years worth of every treatment, surgery and medication available to stop it. If I walk around the block, I give out and have chest pains, he said. Duke cardiologist Dr. Tom Povsic included Darden in a phase 3 trial looking for benefits of a special stem cell therapy to stimulate the growth of new vessels feeding blood to the heart. In certain patients, the arteries can no longer be fixed, or bypass surgery can't be used to fix the arteries. And in those patients, novel therapies are sorely needed, Povsic said. So, the stem cells in this particular case are obtained from the patient themselves. The cells, originating in the bone marrow, are stimulated and released into the blood stream, extracted and then administered directly into the heart through a special catheter. Last week, I was injected with the stem cells, Darden said. I'm excited to be in it, … Continue reading →

Topeka A bill pushed by abortion opponents that would require the Kansas University Medical Center to establish a center that focuses on adult stem cell research will be debated in the Senate on Thursday. Senate Bill 199, which would create the Midwest Stem Cell Therapy Center, was authored by 22 conservative Republican senators, including Senate President Susan Wagle of Wichita, Majority Leader Terry Bruce of Hutchinson, and Public Health and Welfare Chairwoman Mary Pilcher-Cook of Shawnee. "This has the potential of putting Kansas on the map in making actual patient therapies available," Pilcher-Cook said. Gov. Sam Brownback also expressed support for the concept. "Having an adult stem cell center is not only highly plausible, it's being done and used in many places around the world," he said. "If Kansas could take a leadership position in that, it could be a highly useful thing for people to get treatments. There are number of different maladies now being treated by non-controversial stem cell treatments," he said. He added, "Let's see what develops in the process and in the bill." The bill would prohibit the center from using embryonic stem cells or cells taken from aborted fetal tissue. Abortion opponents oppose human embryonic … Continue reading →