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Osiris Rises on European Stem-Cell Drug Title Decision

Posted: Published on February 20th, 2013

Osiris Therapeutics Inc. rose the most in eight months after European regulators transferred the orphan drug title for a stem cell therapy to the company, making it easier to seek a buyer or partner for the treatment. Osiris gained 9 percent to $7.65 at the close in New York, its biggest intraday jump since June. The European Medicines Agency made the title transfer for the intravenous treatment Prochymal, which treats a disease that attacks bone marrow- transplant recipients, Columbia, Maryland-based Osiris said in a statement today. The orphan designation provides 10 years of market exclusivity if the medicine is approved, and the simplifying of who holds the title clears the way for a transaction should Osiris opt to sell Prochymal to another company, said Edward Tenthoff, a senior analyst with Piper Jaffray & Co. in New York. Theyve started to get approvals for Prochymal, said Tenthoff, who has a neutral rating on the stock. Theres a way for them to monetize that. Tenthoff said Osiriss former partner, Sanofis Genzyme unit, probably held Prochymals orphan drug title before. Osiris didnt name the previous title holder in its statement. Osiris had declined 22 percent this year through Feb. 15. An orphan drug … Continue reading

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Stem Cell Therapeutics Announces Joint-Venture Agreement With Reneu Inc. and Nexgen Medical Systems, Inc

Posted: Published on February 20th, 2013

TORONTO, ONTARIO--(Marketwire - Feb 19, 2013) - Stem Cell Therapeutics Corp. (TSX VENTURE:SSS) ("SCT" or the "Corporation") a life sciences company developing stem cell-related technologies, today announced a joint-venture agreement with ReNeu Inc. of Calgary, AB, Canada, ("ReNeu") and NexGen Medical Systems, Inc. of Melbourne, FL, USA ("NexGen"). ReNeu is a company formed to commercialize drug-based therapies to treat central nervous system disorders in combination with devices and processes for direct-to-brain administration. Subject to the definitive agreement, SCT and NexGen will license their respective technologies to ReNeu under world-wide,royalty-free licenses for the use of NexGen''s FDA-cleared EViTAR line of proprietary intracranial delivery systems and SCT''s NTx-265, -428 and -488 covering the proprietary use of drugs for the regeneration of endogenous neural stem cells. To the knowledge of the Corporation the EViTAR intracranial delivery system is the only FDA-cleared Class II medical device currently indicated for the injection of material into the brain during intracranial procedures. It is designed for site-specific, low-volume, high-concentration delivery of drugs to target tissues in the brain of patients suffering from stroke, neurodegenerative disease, and tumors. SCT''s NTx-265 is a therapeutic regimen of approved and clinically well-defined drugs that include human Chorionic Gonadotropin ("hCG") and erythropoietin … Continue reading

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Jelqing – How To Jelq – Jelqing Videos – Penis Enlargement – Video

Posted: Published on February 20th, 2013

Jelqing - How To Jelq - Jelqing Videos - Penis Enlargement http://www.penisaffair.com - Complete guide to jelqing and how to jelq. Free video download. By: michael thomas … Continue reading

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The 5 Deadly Mistakes That Cause Premature Ejaculation And Erectile Dysfunction – Video

Posted: Published on February 20th, 2013

The 5 Deadly Mistakes That Cause Premature Ejaculation And Erectile Dysfunction http://www.endlessman.com In this video you are going to learn The 5 Deadly Mistakes That Cause Premature Ejaculation And Erectile Dysfunction. By: endlessmaninbed … Continue reading

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Women’s Excellence in Bladder Control near Shelby Township, Michigan Now Trialing New Overactive Bladder (OAB) Drug …

Posted: Published on February 20th, 2013

Medications that treat overactive bladder (OAB) have notorious side effects such as dry mouth, constipation, and urinary retention. Womens Excellence in Bladder Control is now trialing and sampling a brand new medication that treats OAB differently. Shelby Township, Michigan (PRWEB) February 20, 2013 Anticholinergic medications used to treat OAB can cause a variety of unpleasant side effects. In most patients, these side effects are mild and tolerable, but in some patients may be severe and intolerable. Common side effects caused by anticholinergic medications include: dizziness, constipation, urinary retention, and dry mouth. These side effects can be severe enough to cause a patient to quit the medication leaving them with no other oral medication option till now. Astellas pharmaceuticals has recently put on the market a new medication to treat OAB, its called Myrbetriq (mirabegron). The agent is as unique as its name and might just become a go to medication for those patients who fail traditional anticholinergic OAB therapy. Myrbetriq is not an anticholinergic drug. It is a beta-3 adrenergic agonist but relaxes the bladder smooth muscle just as anticholinergics do. Myrbetriq can help with symptoms of urge incontinence, urgency, and frequency. It also helps to increase the bladders capacity … Continue reading

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DrugRisk Update: First NuvaRing Lawsuit Starts This Summer As FDA Complaints Rise

Posted: Published on February 20th, 2013

Dallas, TX (PRWEB) February 20, 2013 The birth control resource center at DrugRisk.com is alerting women who have used NuvaRing contraceptive devices of new safety warnings added to the site. Also, complaints to the FDA over the devices continue to rise as trials are set to begin this summer for more than 1,000 cases. DrugRisks mission is to improve patient safety by providing the latest drug warnings, recalls, studies and litigation news. Weve noticed an increase in both injury claims and complaints to the FDA related to NuvaRing following the recent blood clot warnings, explains DrugRisk representative Ryan Mayer. The resource center previously added warnings which link vaginal ring contraceptives such as NuvaRing to higher risks of blood clots than traditional birth control pills. On June 14, 2012, the New England Journal of Medicine published a study finding vaginal ring contraceptives could relate to a 2.5 to 3-fold increased risk of blood clots.* DrugRisk has also discovered that the FDA has received nearly 5,500 adverse event reports of complications among women using NuvaRing devices.** Most common were 1,177 reports of pulmonary embolism and 806 reports of deep vein thrombosis, with hospitalization resulting in over 30% of cases.** The resource center … Continue reading

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DrugRisk Update: Court to Decide Fate of Mirena Lawsuits Next Month

Posted: Published on February 20th, 2013

New York, NY (PRWEB) February 20, 2013 The birth control resource center at DrugRisk.com is alerting women using the IUD contraceptive Mirena of updated legal news added to the site showing a federal court will meet next month to decide the fate of the growing Mirena litigation. DrugRisks mission is to improve patient safety by providing the latest drug warnings,recalls, studies and legal news. This allows users to have informed discussions with their doctors about drug side effects and decide if they need legal advice, explains DrugRisk representative Ryan Mayer. DrugRisk has added information from the FDA showing more than 47,000 patients have filed AERS reports after suffering complications from the Mirena IUD.* Of these, 5079 involved dislocation and 1421 involved migration of the devices, which can perforate or damage the uterine wall.* In more than 6% of cases, patients required hospitalization or surgery. The resource center has also learned that the FDA warned Bayer, the maker of Mirena, about the marketing of the device in 2009, after they failed to disclose safety risks while claiming the devices could help busy moms with intimacy and make them look and feel great.** DrugRisk reported that, with litigation over Mirena perforation growing, … Continue reading

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UF study: Many meth side effects kick in only after stopping

Posted: Published on February 20th, 2013

Methamphetamine crystals in a bag. (AP Photo/DEA) Some of the negative side effects of taking methamphetamines begin only after users have stopped taking them, according to a recent study by University of Florida researchers. A study led by Dr. Habibeh Khoshbouei, an associate professor of neuroscience and psychiatry at the UF College of Medicine, showed that mice withdrawing from methamphetamines had memory loss and a decrease in neuronal activity two weeks after the withdrawal began -- the equivalent of one year in humans. The mice did not have the same symptoms while they were still taking the drugs. It is very well established that people who abuse meth show symptoms of neurodegeneration and psychosis, so long-term meth abuse can produce all sorts of problems, Khoshbouei said. Meth induces an uncontrolled release of dopamine, a neurotransmitter responsible for pleasure. It exposes the brain to too much dopamine, which feels good at the time but has both immediate and long-term consequences namely of killing neurons, said Dr. Jamie Smolen, an addiction psychiatrist at UF. Smolen added that the long-term use of meth might change receptors in the brain permanently, impairing memory, attention span and what is called executive function, or the ability … Continue reading

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U.S. overdose deaths climbs for 11th straight year, driven by painkillers

Posted: Published on February 20th, 2013

Lindsey Tanner And Mike Stobbe, The Associated Press Published Wednesday, Feb. 20, 2013 7:49AM EST CHICAGO -- Drug overdose deaths rose for the 11th straight year, federal data show, and most of them were accidents involving addictive painkillers despite growing attention to risks from these medicines. "The big picture is that this is a big problem that has gotten much worse quickly," said Dr. Thomas Frieden, head of the Centers for Disease Control and Prevention, which gathered and analyzed the data. In 2010, the CDC reported, there were 38,329 drug overdose deaths nationwide. Medicines, mostly prescription drugs, were involved in nearly 60 per cent of overdose deaths that year, overshadowing deaths from illicit narcotics. The report appears in Tuesday's Journal of the American Medical Association. It details which drugs were at play in most of the fatalities. As in previous recent years, opioid drugs -- which include OxyContin and Vicodin -- were the biggest problem, contributing to 3 out of 4 medication overdose deaths. Frieden said many doctors and patients don't realize how addictive these drugs can be, and that they're too often prescribed for pain that can be managed with less risky drugs. They're useful for cancer, "but if … Continue reading

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Drug overdose deaths climbed for 11th straight year, driven by potent, addictive painkillers

Posted: Published on February 20th, 2013

CHICAGO - Drug overdose deaths rose for the 11th straight year, federal data show, and most of them were accidents involving addictive painkillers despite growing attention to risks from these medicines. "The big picture is that this is a big problem that has gotten much worse quickly," said Dr. Thomas Frieden, head of the Centers for Disease Control and Prevention, which gathered and analyzed the data. In 2010, the CDC reported, there were 38,329 drug overdose deaths nationwide. Medicines, mostly prescription drugs, were involved in nearly 60 per cent of overdose deaths that year, overshadowing deaths from illicit narcotics. The report appears in Tuesday's Journal of the American Medical Association. It details which drugs were at play in most of the fatalities. As in previous recent years, opioid drugs which include OxyContin and Vicodin were the biggest problem, contributing to 3 out of 4 medication overdose deaths. Frieden said many doctors and patients don't realize how addictive these drugs can be, and that they're too often prescribed for pain that can be managed with less risky drugs. They're useful for cancer, "but if you've got terrible back pain or terrible migraines," using these addictive drugs can be dangerous, he said. … Continue reading

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