Feb. 6, 2013 Researchers have found a genetic variant that doubles the likelihood that people will have calcium deposits on their aortic valve. Such calcification, if it becomes severe, can cause narrowing or a blockage of the aortic valve, a condition called aortic stenosis. The study is the first large-scale, genome-wide association study to uncover a genetic link to aortic valve calcification. An article detailing the findings is published in the February 7, 2013 issue of The New England Journal of Medicine. The study's lead investigators -- from Johns Hopkins, Harvard University, McGill University, the University of Iceland and the National Institutes of Health -- found that having a genetic variant in the LPA gene, which codes for a type of cholesterol particle called lipoprotein (a), also increases the risk of developing aortic stenosis by more than 50 percent. The researchers say their findings not only help explain why heart valve calcification may run in families, they could also lead to the development of targeted medications that might slow the progression of the disease. Statin medications, which reduce common forms of cholesterol that can clog blood vessels, have not been shown to reduce aortic valve calcification. "This is an important … Continue reading →

4 February 2013 Last updated at 21:33 ET By James Gallagher Health and science reporter, BBC News A tiny "genetic patch" can be used to prevent a form of deafness which runs in families, according to animal tests. Patients with Usher syndrome have defective sections of their genetic code which cause problems with hearing, sight and balance. A study, published in the journal Nature Medicine, showed the same defects could be corrected in mice to restore some hearing. Experts said it was an "encouraging" start. There are many types of Usher syndrome tied to different errors in a patient's DNA - the blueprint for building every component of the body. One of those mutations runs in families descended from French settlers in North America. When they try to build a protein called harmonin, which is needed to form the tiny hairs in the ear that detect sound, they do not finish the job. It results in hearing loss at birth and has a similar effect in the eye where it causes a gradual loss of vision. Scientists at the Rosalind Franklin University of Medicine and Science, in Chicago in the US, designed a small strip of genetic material which attaches … Continue reading →

Natural scaffolds for stem cells... critical step or overhyped?.mp4 http://www.stemcellsarthritistreatment.com There are a number of natural biomaterials that have been used in experiments in tissue engineering. Protein-based compounds include collagen, fibrin, fibrinogen, and silk. Collagen seems to be the most popular of these. I can be transformed into a 3 dimensional matrix. Stem cells are attracted to the scaffold and form blood vessels inside it. Multiple studies have demonstrated that the use of these 3-D collagen scaffolds along with stem cell seeding may have utility in the construction of ligaments, cartilage, and bone. Fibrin, while not studied as much as collagen, also appears to have promise. Silk, used as a 3-D scaffold also has promise. Meinel and colleagues demonstrated that human mesenchymal stem cells combined with silk scaffolds produced more cartilage than comparable collagen 3D scaffolds. Silk has tensile strength that makes it attractive for engineering connective tissue. http By: Nathan Wei … Continue reading →

8 Things You Should Ask Your Stem Cell Physician Devin Stone of MetroMD offers 8 things you should ask your physician prior to engaging in stem cell therapy. By asking the right questions as part of your research, you can ensure the best chances for success and receive a safe and effective treatment. For more info, email us at info@metromd.net or visit MetroMD.net MetroMD Institute of Regenerative Medicine is located in Hollywood, Los Angeles, CA. By: MetroMD … Continue reading →

Stem Cell Therapy With Bob - Thomas Schwarzl - SBI - Runner up 2013 Tom is a science punk from the Alps doing his PhD with Systems Biology Ireland. He likes to challenge everything, discover patterns in high complex problems and making them clear for everyone to understand. Besides his scientific interest in stem cell therapy and cancer research, he likes Post Secret, street art, and is planning a start-up after his PhD. By: thesisin3 … Continue reading →

Pet Surgery | Las Vegas | Veterinary Stem Cell Therapy | TPLO veterinary-stemcell.com 702-250-1888 What is stem cell therapy? Stem cells are the body's repair cells. They have the ability to divide and differentiate into many different types of cells based on where they are needed throughout the body. Stem cells can divide and turn into tissues such as skin, fat, muscle, bone, cartilage, and nerve to name a few. They even possess the ability to replicate into organs such as the heart, liver, intestines, pancreas, etc. Call Dr. Mauer or visit his site today.. Find out if stem cell therapy is right for your pet. By: Roger Mauer … Continue reading →

Stem Cell Therapy For Your Pet | Las Vegas, Nevada | Dr. Roger A. Mauer DVM veterinary-stemcell.com Dr. Mauer is very excited to now be offering Stem Cell Therapy. This innovative and affordable treatment has been making news all over the country. This treatment is completely natural and there are no side effects other than occasional minor swelling at injected joint sites. Most animal owners see results in just days after treatment and their pets benefiting with less or no pain. Stem cells are the body's repair cells. They have the ability to divide and differentiate into many different types of cells based on where they are needed throughout the body. Stem cells can divide and turn into tissues such as skin, fat, muscle, bone, cartilage, and nerve to name a few. They even possess the ability to replicate into organs such as the heart, liver, intestines, pancreas, etc. By: Roger Mauer … Continue reading →

Stem Cell Surgery Study by Dr. Ruth Roberts - Kidney Disease Miracle for Cats and Dogs STEM CELL TRANSPLANT STUDY IN CATS AND DOGS POINTS TO GROUNDBREAKING TREATMENT FOR KIDNEY DISEASE Sabrina is a fourteen-year-old cat, diagnosed with kidney disease. Yet, Sabrina's luck has changed due to a groundbreaking study in cats and dogs for the treatment of kidney disease. The research study by Dr. Ruth Roberts with Sun Dog Cat Moon Veterinary Clinic (SDCM) is stem cell transplant surgery. Sabrina's procedure was on January 21, 2013. During surgery, stem cells were harvested from a four-ounce sample of her own fat tissue. "Modified stem cells find their way to the appropriate locations of the damaged kidneys, engrafting themselves into key areas for renal function, resulting in reduced inflammation, allowing regeneration of tissue and improved function in the kidney. There is a need in veterinary medicine for a regenerative treatment in kidney failure," says Dr. Ruth Roberts For more information on Dr. Ruth Roberts' study on stem cell therapy for chronic renal failure in cats and dogs, please contact SDCM at 843-437-0063 and info@SunDogCatMoon.com. Visit http://www.SunDogCatMoon.com Publicist: Penelope@PenelopeJean.com By: TheFunBunchChannel … Continue reading →

NORTHRIDGE, CA and CAMBRIDGE, UNITED KINGDOM--(Marketwire - Feb 6, 2013) - Avita Medical Ltd. ( ASX : AVH ) ( OTCQX : AVMXY ) Regenerative medicine company Avita Medical Ltd. ( ASX : AVH ) ( OTCQX : AVMXY ) today announced that Dr. Michael S. Perry, Vice President and Senior Global Program Head, Stem Cell Therapy at Novartis Pharmaceuticals Corp., has been appointed to the company's board of directors.Dr. Perry has over 25 years of successful pharmaceutical/biotech management and development experience. Dalton Gooding, Avita Medical chairman, said, "Michael has extraordinary biotech and business expertise, and we are delighted that he is joining Avita's board of directors." Perry currently serves as Vice President and Senior Global Program Head, Stem Cell Therapy at Novartis Pharmaceuticals Corp, a US affiliate of Switzerland-based Novartis AG, a world leader in the research and development of products to protect and improve health and well-being with core businesses in pharmaceuticals, vaccines, consumer health, generics, eye care and animal health. Dr. Perry, based in the United States, has previously served as the Global Head of R&D at Baxter Healthcare, President, Cell & Gene Therapy at Novartis affiliates SyStemix and Genetic Therapy, Inc., VP Regulatory Affairs at Sandoz … Continue reading →

SAN DIEGO, Feb. 7, 2013 (GLOBE NEWSWIRE) -- Fate Therapeutics, Inc., a biopharmaceutical company engaged in the discovery and development of adult stem cell modulators, today announced that Christian Weyer, M.D., M.A.S., President and Chief Executive Officer, will be presenting a company overview at the 15th Annual BIO CEO & Investor Conference at 11:00 a.m. EST on Monday, February 11, 2013, at the Waldorf-Astoria Hotel in New York City. About Fate Therapeutics, Inc. Uniquely positioned at the intersection of stem cell science and orphan disease, Fate Therapeutics is pioneering the discovery and development of adult stem cell modulators in pursuit of innovative therapeutics with the potential to cure or transform the lives of patients with rare life-threatening disorders. The Company's lead program, ProHema, an innovative cord blood-derived cell therapy containing ex-vivo pharmacologically-modulated hematopoietic stem cells (HSCs), is currently in Phase 2 testing in patients with leukemia undergoing hematopoietic transplantation. The Company plans to pursue clinical evaluation of pharmacologically-modulated HSCs in patients with rare genetic disorders, an area of tremendous unmet medical need in which the curative potential of cord blood transplantation is well recognized. In addition, Fate Therapeutics is developing proprietary Wnt7a-based protein therapeutics that have shown efficacy in preclinical … Continue reading →