Autism after stem cell therapy He is a known case of Autism with history of CIAB, but thereafter parents noticed delayed motor milestones in him along with delayed speech and hyperactivity. So at 2 years, he was diagnosed to have Autism and put on rehabilitation program including Occupational Therapy, Physiotherapy and speech therapy. Neurologically, he has near normal tone and reflexes. On examination, he has all sensation intact and no motor weakness. He has normal vision, hearing but bisyllable speech. He has social isolation. He has no bowel and bladder control and has bed wetting present. Functionally, he needs supervision in all ADL and wheel chair bound for mobility On FIM scores he scores 62 On ISAA he scores 130 Stem Cell Therapy done at NeuroGen Brain and Spine Institute Surana Sethia Hospital Sion-Trombay Rd, Suman Ngr Opp Corporate Park, Chembur, Mumbai -- 71. Tel : 022 - 25283706, 022 - 25281610, Mob : +91 9920 200 400 http://www.neurogen.in http://www.stemcellsmumbai.com By: neurogenbsi … Continue reading →

Stem Cell Therapy for Spinal Cord Injury He is a paraplegic has history of fall from height in 1993, leading to fracture D4 and paraplegia with complete bowel bladder loss. He was managed conservatively and has been undergoing rehabilitation since then. Neurologically, he is hypertonic and hyperflexic. On examination: he has sensory loss below T4. He has grade 0 muscle power in bilateral lower extremity and near normal upper extremity. He has no bowel and bladder control and is on condom catheter. He has bilateral knee flexion contracture =10. On ASIA impairment scale he scores'A'. On investigation: MRI: 6/7/2012: Wedge compression of the D4 vertebral body with a focal area of scarring within the spinal canal involving the arachnoid and the spinal cord at D3-4 level. A large cord syrinx extending cranially upto C4vetebral level with a smaller syrinx extending caudally up to D7 vertebral level. EMG / SSEP: It is suggestive of a severe lesion affecting the posterior column conduction from both lower limbs. There is evidence of predominantly Upper motor neurone lesion affecting the lower limbs. Functionally, he needs assistance in most ADL and wheel chair bound for mobility. Stem Cell Therapy done at NeuroGen Brain … Continue reading →

What are the important issues when it comes to cartilage repair... Things you need to know! http://www.stemcellsarthritistreatment.com The first is to know that whatever method is used is effective in building articular cartilage. There are two types of cartilage, hyaline cartilage which is the tough gristle that caps the ends of long bones and fibrocartilage which is the softer cartilage which is found in knee meniscus, and the labral tissue of the shoulder and hip. The second issue is what type of cell to use. Adult autologous mesenchymal stem cells are the ones that are easiest to harvest and to use. But are they the most effective? Allogeneic donor cells may prove to be a more viable source, providing graft versus host reactions will not be an issue. How do we ensure stem cell survival in the hostile environment of an arthritic joint? The use of growth factors and other "protective" factors need to be considered. What is the optimal condition that will ensure a good outcome? Much work has been done in the field of biomaterial scaffolding. Is it really necessary? While in vitro studies and small animal studies appear promising, no definitive human studies have been done. It … Continue reading →

Intracellular distribution of nontargeted quantum dots - Supplementary Video: 39658 Supplementary video of original research "Intracellular distribution of nontargeted quantum dots after natural uptake and microinjection" to be published in the open acesss International Journal of Nanomedicine by Damalakiene L, Bagdonas S, Karabanovas V, et al. Background: The purpose of this study was to elucidate the mechanism of natural uptake of nonfunctionalized quantum dots in comparison with microinjected quantum dots by focusing on their time-dependent accumulation and intracellular localization in different cell lines. Methods: The accumulation dynamics of nontargeted CdSe/ZnS carboxyl-coated quantum dots (emission peak 625 nm) was analyzed in NIH3T3, MCF-7, and HepG2 cells by applying the methods of confocal and steady-state fluorescence spectroscopy. Intracellular colocalization of the quantum dots was investigated by staining with Lysotracker. Results: The uptake of quantum dots into cells was dramatically reduced at a low temperature (4C), indicating that the process is energy-dependent. The uptake kinetics and imaging of intracellular localization of quantum dots revealed three accumulation stages of carboxyl-coated quantum dots at 37C, ie, a plateau stage, growth stage, and a saturation stage, which comprised four morphological phases: adherence to the cell membrane; formation of granulated clusters spread throughout the cytoplasm; localization of … Continue reading →

Nutrition and Fitness Health Home>>Nutrition and Fitness>>Health news Written by: QMI Agency Feb. 6, 2013 (SHUTTERSTOCK) Scientists at the Ottawa Hospital Research Institute say they have discovered a trigger that turns muscle stem cells into brown fat, a form of good fat that could play a critical role in the fight against obesity. "This discovery significantly advances our ability to harness this good fat in the battle against bad fat and all the associated health risks that come with being overweight and obese," Dr. Michael Rudnicki, a senior scientist at the Institute, said in a statement Tuesday. The research team say mice that were injected with an agent to reduce a gene regulator called miR-133 produced more brown fat, were protected from obesity and had an improved ability to process glucose. Did you find what you were looking for on our website? Please let us know. See original here: Stem cell discovery identifies potential obesity treatment … Continue reading →