LOS ANGELES, Jan. 30, 2013 /PRNewswire/ --NeuroSigma, Inc., a California-based medical device company, today announced the publication of a positive Phase II clinical study for the use of external Trigeminal Nerve Stimulation (eTNS) for the treatment of drug-resistant epilepsy. The study, led by Christopher M. DeGiorgio, M.D., Professor of Neurology at the University of California, Los Angeles (UCLA) and Vice President of Neurology at NeuroSigma, was published online in the January 30, 2013 issue of Neurology, the medical journal of the American Academy of Neurology. NeuroSigma is the exclusive worldwide licensee of UCLA's entire TNS intellectual property portfolio. Drug resistant epilepsy (DRE) is a serious medical disorder, and affects approximately 30% of the estimated 50 million people with epilepsy worldwide. Today's publication details the results of a double-blind randomized controlled trial of eTNS in 50 subjects with DRE. The trial demonstrated that among patients receiving eTNS there were significant reductions in seizure frequency over the course of the 18-week study. Patients receiving eTNS also demonstrated significant improvements in mood, making eTNS unique among epilepsy therapies. The clinical trial was conducted at UCLA and the University of Southern California (USC). "This randomized controlled trial provides Level II evidence that eTNS may … Continue reading
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