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Family, friends bet on Bedard

Posted: Published on January 26th, 2013

Buy This Photo Alexandra Bedard and her father, Marc, attend Friday night's Texas Hold'em benefit for the York 23-year-old, who suffered a serious spinal cord injury in a 2011 motorcycle crash.Molly McPherson photo YORK, Maine The American Legion Post 56 was flush with nearly 50 serious Texas Hold'em poker players who were participating in a tournament to help raise funds for a young York mother's treatment for a serious spinal injury. Alexandra Bedard, 23, who was paralyzed in 2011 after she was involved in a motorcycle accident as a passenger, needs to eventually raise more than $100,000 to continue her therapy at Project Walk, a spinal cord injury recovery center in Carlsbad, Calif. Bedard spent 21 days at the center last December to evaluate her injuries and start her treatment plan; however, she was forced to return home prematurely due to lack of funds. By combining Friday night's proceeds with the $22,000 previously raised, Captain Gary Woods of the York Beach Fire Department said it would be possible for Bedard to continue her treatment as soon as February. Woods, a family friend who is leading the fund-raising efforts on behalf of the former York Beach Junior Firefighter, said it was … Continue reading →

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Paralyzed Tyngsboro Teen Headed To Atlanta For Therapy

Posted: Published on January 26th, 2013

TYNGSBORO (CBS) You can tell from high flying jumps on YouTube, 17-year-old Jack Trottier knows how to snowboard. Hes gone off 50-foot jumps. Something like this you never thought would happen. Its just an accident, his dad Bill Trottier said. He says last week his son was snowboarding with some friends at a neighbors house in Tyngsboro, when he went of a two-foot jump and landed the wrong way. He went off one of the jumps and lost his balance and came down on the side of his neck and shoulder, Bill said. Even though Jack was wearing his helmet, he suffered a severe spinal cord injury and is now paralyzed from the chest down. He cant move his legs or his arms, Bill said. Jack is now on his way to undergo intense therapy at the Shepherd Center in Atlanta. Its the same place where Norwood hockey player Matt Brown received treatment for his injury. Jack not only loved snowboarding, but he also was a star athlete at Tyngsboro High School. He was the starting quarterback as junior and led his team to a 10-2 record last season. He is our leader. He was the guy who had the … Continue reading →

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Foundation Venture Capital Group Invests In Start-Up Working to Reduce Side Effects of Parkinson's Treatment

Posted: Published on January 26th, 2013

NEW BRUNSWICK, N.J., Jan. 25, 2013 /PRNewswire-USNewswire/ -- Parkinson's disease affects one million people in the United States and seven million worldwide. While L-Dopa is effective in treating the disease symptoms, the vast majority of patients taking it chronically eventually develop L-Dopa Induced Dyskinesia (LID), abnormal involuntary movements that can be disabling. A new company, MentiNova, Inc., is exploring an oral medication that could reduce these uncontrollable, often chaotic movements in patients being treated with L-Dopa. Foundation Venture Capital Group (FVCG), a New Jersey Health Foundation affiliate, has committed up to $500,000 to advance this research and development. According to James M. Golubieski, president of FVCG, the investment in MentiNova will allow the company to advance the status of its IND (Investigational New Drug) filing with the FDA and to perform clinical trials testing the efficacy of the treatment. Dr. M. Maral Mouradian, the William Dow Lovett Professor of Neurology and Director of the Center for Neurodegenerative and Neuroimmunologic Diseases at the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School in Piscataway, NJ, is a co-founder of the company. Dr. Mouradian said MentiNova's focus at this time is to use a drug that is currently clinically … Continue reading →

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Researchers at Scripps to Study Possible New Treatment for Parkinson's Disease

Posted: Published on January 26th, 2013

SAN DIEGO, Jan. 25, 2013 /PRNewswire/ -- Scripps Clinic, in partnership with The Scripps Research Institute (TSRI), has begun the research phase of a proposed clinical trial using induced pluripotent stem cells to halt or reverse the effects of Parkinson's disease. (Logo: http://photos.prnewswire.com/prnh/20121018/LA95241LOGO) Under the leadership of Melissa Houser, MD, neurologist and medical director of Scripps Clinic's Parkinson's Disease and Movement Disorders Center, and co-investigator Jeanne F. Loring, PhD, professor and director of the Center for Regenerative Medicine at TSRI, skin cells taken from Parkinson's disease patients who meet select criteria are being cultivated in vitro and turned into pluripotent stem cells. These stem cells will be developed into dopamine-producing brain cells. The plans, which will require Food and Drug Administration (FDA) approval, are to implant these cells back into the donor patients' brains; the goal is for the cells to integrate inside the brain and produce enough dopamine to alleviate the worst symptoms of Parkinson's disease. There are currently several clinical trials using pluripotent stem cells to replace cells lost to injury or neurodegenerative disease, as well as for the development of pharmaceuticals, but reimplantation of cells into the same patient for function restoration as a treatment for Parkinson's … Continue reading →

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Biogen Advances with MS Candidate

Posted: Published on January 26th, 2013

Biogen Idec (BIIB) recently announced positive top-line data on its phase III multiple sclerosis candidate, peginterferon beta-1a. Results from the ADVANCE study showed that peginterferon beta-1a met the primary endpoint as well as secondary endpoints. Detailed Results Two doses (once in two weeks and once in four weeks) of peginterferon beta-1a were compared to placebo in the study that was conducted to evaluate the safety and efficacy of the candidate in patients suffering from relapsing-remitting multiple sclerosis (RRMS). Both dosing regimens met the primary endpoint of annualized relapse rate (ARR) at one year. While ARR reduction was 35.6% in the two-week regimen, the four-week regimen saw a 27.5% reduction in ARR. Secondary endpoints included reduction of the risk of 12-week confirmed disability progression as measured by the Expanded Disability Status Scale (38% for both dosing arms), reduction in the proportion of patients who relapsed (39% the two-week dosing arm and 26% in the four-week dosing arm) and reduction in the number of new or newly enlarging T2-hyperintense lesions on brain MRI scans (67% in the two-week dosing arm and 28% in the four-week dosing arm). Biogen said that safety and tolerability profiles were favorable in both arms. Biogen intends to … Continue reading →

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Healthy Living: High MS rates in Upstate NY

Posted: Published on January 26th, 2013

400,000 Americans have multiple sclerosis. Effects range from vision and speech impairment to balance issues and permanent disabilities. As our Katie Gibas reports, Upstate New York has some of the highest MS rates in the country. To view our videos, you need to enable JavaScript. Learn how. install Adobe Flash 9 or above. Install now. Then come back here and refresh the page. Brenda Irving has been living with multiple sclerosis since she was 23. Susan Peck was diagnosed 11 years ago. For both women, it was a scary and sudden onset. "I was on vacation with my husband and my mom and dad, and we were just enjoying the vacation and I woke up blind," said Brenda Irving, who has multiple sclerosis. Susan Peck, who also has multiple sclerosis added, "I woke up one morning and my entire right side was numb, my arm was numb and tingly." 400,000 Americans have MS. Effects range from vision and speech impairment to balance issues and permanent disabilities. "It feels like a leg or a foot might not work. It changes each day. I say put your best forward, no matter what stage of MS you have, and each hour, that might … Continue reading →

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Stem Cell Research Articles – Video

Posted: Published on January 26th, 2013

Stem Cell Research Articles URL: http://www.blackhatworld.com By: Jakes Bling … Continue reading →

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ARUP to Offer Carrier Screening for Over 100 Genetic Disorders

Posted: Published on January 26th, 2013

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)-- Counsyl has partnered with ARUP Laboratories, a nonprofit enterprise of the University of Utah, to expand its pre-pregnancy and early pregnancy genetic test offering for prospective parents. ARUPs molecular genetic testing laboratory already provides a comprehensive set of testing options for a broad range of inherited disorders. The partnership with Counsyl complements ARUPs existing services for genomic medicine. Dr. Sherrie Perkins, Chief Medical Officer at ARUP, stated, We are pleased that the relationship with Counsyl now allows ARUP to offer testing for over 100 recessive genetic disorders to more than half of the nations university, teaching and childrens hospitals. Included in the Counsyl Test are life-threatening conditions, such as spinal muscular atrophy, Smith-Lemli-Opitz, and Tay-Sachs disease. Several inherited metabolic disorders that can be treated with dietary modifications and supplements are also part of the test. ARUP has historically used innovation and technology to support their clients need for specialty testing. For tests not performed at ARUP, high-quality test performance and exceptional clinical utility are the two primary criteria used to establish external partnerships. Counsyl uses high throughput technology to simultaneously screen for over 400 genetic variants from one tube of blood. Ramji Srinivasan, CEO of … Continue reading →

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Study shows potential of differentiated iPS cells in cell therapy without immune rejection

Posted: Published on January 26th, 2013

A new study from Boston University School of Medicine (BUSM) shows that tissues derived from induced pluripotent stem (iPS) cells in an experimental model were not rejected when transplanted back into genetically identical recipients. The study, published online in Cell Stem Cell, demonstrates the potential of utilizing iPS cells to develop cell types that could offer treatment for a wide range of conditions, including diabetes, liver and lung diseases, without the barrier of immune rejection. Ashleigh Boyd, DPhil, and Neil Rodrigues, DPhil, the study's senior authors, are assistant professors of dermatology at BUSM and researchers at the Center for Regenerative Medicine (CReM) at Boston University and Boston Medical Center (BMC). They also are lead investigators at the National Institutes of Health's Center of Biomedical Research Excellence (COBRE) at Roger Williams Medical Center, a clinical and research affiliate of BUSM. iPS cells can be developed from adult cell types, such as skin or blood, by returning them to a stem cell state using genetic manipulation. iPS cells are capable of maturing (differentiating) into all the specific cell types in the body, making them a powerful tool for biological research and a source of tissues for transplantation based therapies. Given that iPS … Continue reading →

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Study explores potential benefits, threats of nanotechnology research

Posted: Published on January 26th, 2013

Every day scientists learn more about how the world works at the smallest scales. While this knowledge has the potential to help others, it's possible that the same discoveries can also be used in ways that cause widespread harm. A new article in the journal Nanomedicine, born out of a Federal Bureau of Investigation workshop held at the University of Notre Dame in September 2012, tackles this complex "dual-use" aspect of nanotechnology research. "The rapid pace of breakthroughs in nanotechnology, biotechnology, and other fields, holds the promise of great improvements in areas such as medical diagnosis and treatment" says Kathleen Eggleson, a research scientist in Notre Dame's Center for Nano Science and Technology and the author of the study. "But the risk of misuse of these breakthroughs rises along with the potential benefit. This is the essence of the 'dual-use dilemma.'" The report examines the potential for nano-sized particles (which are measured in billionths of a meter) to breach the blood-brain barrier, the tightly knit layers of cells that afford the brain the highest level of protectionfrom microorganisms, harmful molecules, etc.in the human body. Some neuroscientists are purposefully engineering nanoparticles that can cross the blood-brain barrier (BBB) so as to … Continue reading →

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