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Clinical trial finds intensive treatment highly effective for children with high-functioning autism

Posted: Published on January 12th, 2013

Jan. 11, 2013 In a second randomized clinical trial, researchers at the Institute for Autism Research at Canisius College have found a comprehensive summer treatment (summer Max) to be highly effective for children with high-functioning autism spectrum disorders (HFASDs). Children with the disorders endure lifelong impairments involving social and social-communicative functioning and restricted and repetitive interests and behaviors. Despite their significant needs, few comprehensive programs have been developed and validated for children with HFASDs. Results of this randomized clinical trial found the comprehensive summer treatment to be effective in improving the social performance and clinical symptoms of children with HFASDs. According to Marcus L. Thomeer, PhD and Christopher Lopata, PsyD, the study's lead authors, the findings, which appeared in the journal, Psychology in the Schools (December 2012), supports and extends the findings of a previous randomized trial that initially demonstrated the efficacy of the manualized treatment. Following the 5-week program, children in the treatment group demonstrated significantly higher scores on child measures of non-literal language skills and knowledge of appropriate social behaviors, as well as significantly higher parent-ratings for targeted and broader social skills and significantly lower ratings of autism symptoms compared to children in the control group. Secondary staff … Continue reading

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Research and Markets: Acute Ischemic Stroke (Event Driven) – A Leading Cause of Death and Neurological Disability …

Posted: Published on January 12th, 2013

DUBLIN--(BUSINESS WIRE)-- Research and Markets (http://www.researchandmarkets.com/research/pq3frt/acute_ischemic) has announced the addition of Decision Resources, Inc's new report "Acute Ischemic Stroke (Event Driven)" to their offering. Acute ischemic stroke (AIS) is one of the leading causes of death and neurological disability worldwide: in 2010, we estimate, 1.8 million ischemic strokes occurred in the seven major pharmaceutical markets. Fifteen years after its approval, recombinant tissue plasminogen activator (rt-PA; alteplase [Genentech's Activase, other brands]) remains the only pharmacological therapy approved for the acute treatment of ischemic stroke in all markets under study. However, because of strict inclusion criteria and safety concerns, the drug is administered to fewer than 5% of diagnosed patients. Given the staggering societal costs of stroke and the historical propensity for investigational drugs to fail in the pipeline, there remains a dire need and enormous opportunity for alternative treatmentsbe they thrombolytic, neuroprotective, or neurorestorative drugs or devicesthat can safely and more effectively treat a greater proportion of AIS patients. Key Topics Covered: Executive Summary What are the key parameters of the acute ischemic stroke market? What factors are driving the market for acute ischemic stroke therapies? What factors are constraining the market for acute ischemic stroke therapies? What are the drug … Continue reading

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Andrew Marr Responding Well To Treatment After Stroke

Posted: Published on January 12th, 2013

BBC presenter Andrew Marr is said to be "responding to medication and continuing to progress" following his hospitalisation after suffering what is believed to have been a stroke. The political correspondant, and host of The Andrew Marr Show, was taken to hospital after falling ill on Tuesday (Jan 8). Marr was well-known for his active lifestyle, especially his commitment to long-distance running, as such the news of his stroke has come as a surprise to many. Fortunately though, a spokesperson for the BBC confirmed earlier today that Marr is in fact on his way to recovery and is now conscious and engaging in conversation with his family, who are remaining at the 53-year-old's bedside while he recovers. The spokesperson said: "Andrew Marr is responding to medication and continuing to progress. He is conscious and eating. He and his family are touched by all the warm wishes and support flooding in." The BBC have also confirmed that, despite his absence, the radio and television shows fronted by Marr will continue to run as before. The Andrew Marr Show and his Radio 4 show, Start The Week, will be fronted by different guest presenters in his absence, with journalist Anne McElvoy to … Continue reading

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Medical First! New Hope For The Paralyzed

Posted: Published on January 12th, 2013

BACKGROUND: Damage to any part of the spinal cord or nerves surrounding the spinal canal usually causes permanent changes in body functions below the site of injury. A traumatic spinal cord injury can come from traumatic blows to the spine that can dislocate, fracture, compress, or crush the vertebrae. Common causes of a spinal cord injury are falls, acts of violence, alcohol, motor vehicle accidents, and sport injuries. Additional damage can come from bleeding, inflammation, swelling, and fluid accumulation around the spinal cord that has gone untreated. A non-traumatic spinal cord injury is caused by cancer, arthritis, infections, inflammation, or disc degeneration of the spine. Researchers around the world have high hopes that advances in research will someday make the repair of spinal cord injuries possible. (Source: webmd.com) TYPES/SIGNS: The ability to control the limbs after a spinal cord injury depends on two things: the place of the injury along the spinal cord and the severity. The lowest part of the spinal cord is referred to as the neurological level of the injury. The severity is classified as either complete or incomplete. A complete injury is when almost all sensory and ability to control movement are lost below the spinal … Continue reading

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First test to detect Parkinson's disease developed by studying tissue taken from under the jaw

Posted: Published on January 12th, 2013

Doctors say tissue sample taken from the saliva glands could reveal abnormal protein, which is tell-tale sign But charity warns the study was small and too invasive to become a routine test By Anna Hodgekiss PUBLISHED: 12:06 EST, 11 January 2013 | UPDATED: 12:14 EST, 11 January 2013 Former boxer Muhammad Ali is one of world's best-known people to suffer from Parkinson's disease, for which is there is no diagnostic test Scientists have developed the first diagnostic test to detect Parkinson's disease. The new test is based on taking a tissue sample from the saliva glands found under the lower jaw. Currently, there are no tools to detect the devastating condition that mainly affects people aged over fifty. Instead doctors base a diagnosis on common symptoms, which include slowness, stiffness of muscles and tremors. Described as a 'big step forward' for treatment, scientists now suggest a portion of a person's saliva gland can show up the illness. Dr Charles Adler, a neurologist at the Mayo Clinic, Arizona, said: 'There is currently no diagnostic test for Parkinson's disease. See original here: First test to detect Parkinson's disease developed by studying tissue taken from under the jaw … Continue reading

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Run for a cause tomorrow

Posted: Published on January 12th, 2013

A fundraiser will be organised by Ambattur-based Bal Sanjeevani Cerebral Palsy Rehabilitation Centre on January 13. Marathons and cycling trips will be a part of Dawn to Dusk 2013 which will be flagged off at IIT-Madras. Marathoner Neville Jamshed Bilimoria and his teammates will cover close to 150 km in 12 hours. The marathon, which will begin with a six-hour run at IIT-Madras by Neville, will be followed by six hours of non-stop cycling from IIT, past Mamallapuram and back. The event is also open to children who can participate in the 500 metres, 1 km, 2 km, 3 km, and 4 km Kids Run which will begin at 9.30 a.m. Funds raised from this event will help the Centre provide children with splints, wheelchairs, walking-aids, and Therasuits, among other immediate needs, said Ravi Subramaniam, chairman of Bal Sanjeevani Cerebral Palsy Rehabilitation Centre. The organisation provides treatment and rehabilitation to over 600 children. For details on registration for the marathon, log on to http://eventjini. com/DawntoDusk/ Registration. More here: Run for a cause tomorrow … Continue reading

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Assisted suicide ban cannot be diluted even in 'harrowing' case of MS sufferer

Posted: Published on January 12th, 2013

The Irish Times - Friday, January 11, 2013 MARY CAROLAN The absolute ban on assisted suicide is fully justified under the Constitution to protect the most vulnerable in society and cannot be diluted even in the harrowing case of a woman terminally ill with multiple sclerosis, the High Court has ruled. However, the three-judge court said it was sure the DPP would act in a humane and sensitive way in considering whether to prosecute any assisted suicide of Marie Fleming. Giving the courts judgment, president of the High Court Mr Justice Nicholas Kearns, with Mr Justice Paul Carney and Mr Justice Gerard Hogan, said unravelling even a thread of the ban, by even a limited constititional finding in favour of Ms Fleming, would, or might, open a Pandoras box which thereafter would be impossible to close. Fundamental objective The State is committed under the Constitution to protecting the sanctity of all human life and valuing equally the life of all persons. The ban was rationally connected to that fundamental objective and not remotely based on arbitrary, unfair or irrational considerations. In the eyes of the Constitution, the last days of the life of a terminally ill and disabled patient facing … Continue reading

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Teva Asks FDA Not to Approve New MS Drugs Till Advisers Evaluate Safety

Posted: Published on January 12th, 2013

By Dow Jones Business News, January 09, 2013, 03:08:00 PM EDT By Peter Loftus Teva Pharmaceutical Industries Ltd. ( TEVA ), which sells the blockbuster multiple-sclerosis drug Copaxone, has asked the U.S. Food and Drug Administration not to approve any new MS drugs until their safety risks have been evaluated by outside advisers. Teva's petition is aimed at Biogen Idec Inc. ( BIIB ), which expects an FDA decision by late March on Biogen's application to market a new MS treatment, known as BG-12, an orally administered pill that analysts expect will be a formidable competitor to the injected Copaxone. In a Dec. 31 citizen petition to the FDA, Teva asked the agency not to approve any new MS drugs until the agency refers them to an advisory committee for evaluation. Advisory committees sometimes review new drug applications to provide guidance to the agency. Teva said it was important for the agency to hear outside advisers' evaluations of any safety risks, in light of risks that have emerged after MS treatments were approved in recent years, including Biogen's own Tysabri MS treatment. Tysabri was removed from the market soon after its 2004 introduction after some recipients experienced a serious brain … Continue reading

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Herbal treatments for postmenopausal symptoms can be recommended as an alternative to HRT

Posted: Published on January 12th, 2013

Public release date: 10-Jan-2013 [ | E-mail | Share ] Contact: Rebecca Jones rjones@rcog.org.uk 020-777-26444 Wiley Herbal and complementary medicines could be recommended as an alternative to hormone replacement therapy (HRT) for treating postmenopausal symptoms says a new review published today in The Obstetrician and Gynaecologist (TOG). The review outlines the advantages and limitations of both pharmacological and herbal and complementary treatments for women with postmenopausal symptoms. The menopause is defined as the time after a woman's menstrual periods have ceased (12 months after a woman's final menstrual period). It is associated with an estrogen deficiency and can cause an increase in vasomotor symptoms (hot flushes), genitourinary symptoms (vaginal dryness, sexual dysfunction, frequent urinary tract infections, urinary incontinence), and musculoskeletal symptoms (joint pain) as well as sleep and mood disturbance. One of the most common menopausal symptoms is hot flushes; approximately two-thirds of postmenopausal women will experience them, and 20% of women can experience them for up to 15 years, states the review. Estrogen deficiency can also lead to longer-term health issues such as cardiovascular disease and osteoporosis. While pharmacological agents are available to treat postmenopausal symptoms, many non-pharmacological treatment options are also available. HRT is the most effective treatment … Continue reading

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Herbal treatments for postmenopausal symptoms may be recommended as an alternative to hormone replacement therapy

Posted: Published on January 12th, 2013

Jan. 10, 2013 Herbal and complementary medicines could be recommended as an alternative to hormone replacement therapy (HRT) for treating postmenopausal symptoms says a new review published January 11 in The Obstetrician and Gynaecologist (TOG). The review outlines the advantages and limitations of both pharmacological and herbal and complementary treatments for women with postmenopausal symptoms. The menopause is defined as the time after a woman's menstrual periods have ceased (12 months after a woman's final menstrual period). It is associated with an estrogen deficiency and can cause an increase in vasomotor symptoms (hot flushes), genitourinary symptoms (vaginal dryness, sexual dysfunction, frequent urinary tract infections, urinary incontinence), and musculoskeletal symptoms (joint pain) as well as sleep and mood disturbance. One of the most common menopausal symptoms is hot flushes; approximately two-thirds of postmenopausal women will experience them, and 20% of women can experience them for up to 15 years, states the review. Estrogen deficiency can also lead to longer-term health issues such as cardiovascular disease and osteoporosis. While pharmacological agents are available to treat postmenopausal symptoms, many non-pharmacological treatment options are also available. HRT is the most effective treatment of hot flushes, improving symptoms in 80 -- 90% of women, says … Continue reading

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