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Revalesio's RNS60 Protects Myelin and Halts Multiple Sclerosis in Mice

Posted: Published on January 3rd, 2013

TACOMA, Wash., Jan. 3, 2013 /PRNewswire/ --Results from a collaborative project between Revalesio and Dr. Kalipada Pahan at Rush University showed remarkable therapeutic activity of Revalesio's novel therapeutic RNS60 in a mouse model of multiple sclerosis (MS). In a study recently published in the journal PLOS ONE, RNS60 halted disease progression (as measured by progressive limb paralysis), prevented inflammation in the brain and spinal column while also protecting against demyelination, a process that makes nerve cells lose their protective covering. The research demonstrated that administration of RNS60 - either at early disease onset or late at the relapsing phase - halted disease progression. Animals treated with RNS60 were protected from infiltration of inflammatory cells to the central nervous system, and thus had a significant preservation of the protective nerve covering (myelin). The full details of the study can be found in the journal PLOS ONE (Protection of Tregs, Suppression of Th1 and Th17 Cells, and Amelioration of Experimental Allergic Encephalomyelitis by a Physically-Modified Saline - December 20, 2012). The study revealed further that RNS60 changed the over-reactive immune response associated with MS through increasing the population of regulatory T cells, which have protective function, while reducing the number of inflammatory … Continue reading →

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Hormonal Replacement Therapy.flv – Video

Posted: Published on January 3rd, 2013

Hormonal Replacement Therapy.flv By: Yel Pamplona … Continue reading →

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Advances in Heart Failure Treatment and Transplant – Video

Posted: Published on January 3rd, 2013

Advances in Heart Failure Treatment and Transplant Dr. Joseph Clemente, host of MHC-TV, interviews Mark J. Zucker, MD, JD, Director, Heart Failure Treatment and Transplant Program at Newark Beth Israel Medical Center. They discuss getting a heart transplant, other treatments such as the Left Ventricular Assist Device (LVAD), and about stem cell research ongoing today. By: barnabashealth … Continue reading →

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Sanford-Burnham and Intrexon Corporation establish collaboration to accelerate stem cell research

Posted: Published on January 3rd, 2013

Public release date: 3-Jan-2013 [ | E-mail | Share ] Contact: Heather Buschman hbuschman@sanfordburnham.org 858-795-5343 Sanford-Burnham Medical Research Institute LA JOLLA, Calif., January 3, 2013 Sanford-Burnham Medical Research Institute, a nonprofit research institution and one of the largest iPSC generators in the world, and Intrexon Corporation, a leading synthetic biology company, today announced a new collaboration to accelerate stem cell research. Under the agreement, Sanford-Burnham will gain access to sophisticated proprietary cellular selection and gene regulation technologies that are not currently on the market, including Intrexon's Laser-Enabled Analysis and Processing (LEAP) instrument and RheoSwitch Therapeutic System (RTS). As part of the agreement, Intrexon may obtain commercial and intellectual property rights resulting from technological advances made under the collaboration. "I'm looking forward to merging and melding our expertise," said Evan Y. Snyder, M.D., Ph.D., professor and director of Sanford-Burnham's Stem Cell Research Center and Stem Cell and Regenerative Biology Program. "We'll bring our iPSC and gene therapy expertise to the table. Likewise, our colleagues at Intrexon will share their knowledge of how best to use the technologies. We envision we'll be meeting with them frequently and sharing insights to further advance the platforms for stem cell applications." Sanford-Burnham is currently building … Continue reading →

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Hope in 10 cancer breakthroughs

Posted: Published on January 3rd, 2013

Where do your cancer research dollars go? The mission that we have is to eventually create a world where Canadians don't have to fear cancer and in order to not fear cancer, we have to be able to understand it, says Luba Slatkovska, senior manager of research at the Canadian Cancer Society. The only way to understand cancer is to research. To shine a light on the life-saving and life-enhancing potential of cancer research, the Canadian Cancer Society has selected the top 10 cancer research highlights of 2012. These discoveries help reduce cancer rates, reduce mortality, and improve the quality of life for those diagnosed with cancer. These 10 exciting findings were chosen from 730 research projects supported by the Canadian Cancer Society in 2012. 1. Decoding a deadly form of breast cancer will lead to more personalized treatments An international team of scientists led by Dr. Sam Aparicio in Vancouver decoded, for the first time, the genetic makeup of triple-negative breast cancer. This breakthrough could help change the way this difficult-to-treat disease is diagnosed and may be the foundation for the next generation of treatments. 2. MAGIC team finds new ways to treat malignant childhood brain cancer Dr. Michael … Continue reading →

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International Stem Cell Corporation to Participate in Biotech Showcase 2013 on January 7th

Posted: Published on January 3rd, 2013

CARLSBAD, CA--(Marketwire - Jan 3, 2013) - International Stem Cell Corporation ( OTCQB : ISCO ) (www.internationalstemcell.com) ("ISCO" or "the Company"), a California-based biotechnology company focused on therapeutic and research products, today announced that Executive Vice President, Dr. Simon Craw, will present at the Biotech Showcase 2013 on Monday, January 7th at 9:30 a.m. PST. The conference is being held in San Francisco at the Parc 55 Wyndham Union Square Hotel. Biotech Showcase 2013 conference presentation details:Date: Monday, January 7, 2013 Time: 9:30 pm PST Location: Parc 55 Wyndham Union Square Hotel, San Francisco, CA Room: Room Mission II - Track C Conference details: http://www.ebdgroup.com/bts/index.php Please contact the conference organizers if you have an interest in attending the conference or if you would like to arrange a meeting with International Stem Cell Corporation's management team. To register for the event, please visit the conference website at http://www.ebdgroup.com/bts/registration/index.php. You may also contact Mark McPartland with MZ Group via email markmcp@mzgroup.us or phone 212-301-7130 to arrange a meeting with management at the conference. Biotech Showcase 2013 is an investor and partnering conference devoted to providing private and public biotechnology and life sciences companies with an opportunity to present to, and meet with, … Continue reading →

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Professor Discovers New Information in the Understanding of Autism and Genetics

Posted: Published on January 3rd, 2013

Newswise WASHINGTON (Jan. 3, 2012) Research out of the George Washington University (GW), published in the journal Proceedings of the National Academy of Sciences (PNAS), reveals another piece of the puzzle in a genetic developmental disorder that causes behavioral diseases such as autism. Anthony-Samuel LaMantia, Ph.D., professor of pharmacology and physiology at the GW School of Medicine and Health Sciences (SMHS) and director of the GW Institute for Neuroscience, along with post-doctoral fellow Daniel Meechan, Ph.D. and Thomas Maynard, Ph.D., associate research professor of pharmacology and physiology at GW SMHS, authored the study titled Cxcr4 regulation of interneuron migration is disrupted in 22q11.2 deletion syndrome. For the past nine years, LaMantia and his colleagues have been investigating how behavioral disorders such as autism, attention deficit hyperactivity disorder (ADHD), and schizophrenia arise during early brain development. His work published in PNAS focuses specifically on the effects diminished 22q11.2 gene dosage has on cortical circuit development. This research shows for the first time that genetic lesions known to be associated with autism and other behavioral diseases disrupt cellular and molecular mechanisms that ensure normal development of a key type of cortical neuron: the interneuron. LaMantia and his colleagues had found previously that … Continue reading →

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GW professor discovers new information in the understanding of autism and genetics

Posted: Published on January 3rd, 2013

Public release date: 3-Jan-2013 [ | E-mail | Share ] Contact: Lisa Anderson lisama2@gwu.edu 202-994-3121 George Washington University WASHINGTON (Jan. 3, 2012) Research out of the George Washington University (GW), published in the journal Proceedings of the National Academy of Sciences (PNAS), reveals another piece of the puzzle in a genetic developmental disorder that causes behavioral diseases such as autism. Anthony-Samuel LaMantia, Ph.D., professor of pharmacology and physiology at the GW School of Medicine and Health Sciences (SMHS) and director of the GW Institute for Neuroscience, along with post-doctoral fellow Daniel Meechan, Ph.D. and Thomas Maynard, Ph.D., associate research professor of pharmacology and physiology at GW SMHS, authored the study titled "Cxcr4 regulation of interneuron migration is disrupted in 22q11.2 deletion syndrome." For the past nine years, LaMantia and his colleagues have been investigating how behavioral disorders such as autism, attention deficit hyperactivity disorder (ADHD), and schizophrenia arise during early brain development. His work published in PNAS focuses specifically on the effects diminished 22q11.2 gene dosage has on cortical circuit development. This research shows for the first time that genetic lesions known to be associated with autism and other behavioral diseases disrupt cellular and molecular mechanisms that ensure normal development … Continue reading →

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Drug Fulfills Promise Of Research Into Cystic Fibrosis Gene

Posted: Published on January 3rd, 2013

Emily Schaller suffers from cystic fibrosis. New treatments that target the genetic basis of her disease allow her to live an active, healthy life. The promise of genetic medicine is beginning to be fulfilled, but it's been a long, hard slog. Take the story of Kalydeco. It's designed to treat people with a lung disease called cystic fibrosis. While not quite a cure, the drug is extremely effective for some CF patients. But the success of Kalydeco has been more than two decades in the making. A good starting point for the story is Aug. 24, 1989. That's the day scientists from the U.S. and Canada announced the discovery of the gene associated with the disease. It was the early days of gene hunting, and the CF gene was a big prize. CF is the most common genetic disease in Caucasians. When people inherit a damaged form of the CF gene, a critical protein inside cells doesn't work properly. As a result, sticky mucus builds up in a patient's lungs, causing infections and making it hard to breathe. The announcement was supposed to be made in conjunction with three papers in the Sept. 8 issue of Science, but a reporter … Continue reading →

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ABC Suzanne Somers Tries New Stem Cell Treatment – Video

Posted: Published on January 3rd, 2013

ABC Suzanne Somers Tries New Stem Cell Treatment By: Joel Aronowitz … Continue reading →

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