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Dramatic Rise in Stem Cell Therapy Use in 2012

Posted: Published on November 27th, 2012

PHILADELPHIA, Nov. 26, 2012 /PRNewswire/ --RRY Publications LLC today announced that the use of stem cell therapies in 2012 significantly exceeded forecasts which were originally presented at the February 2012 New York Stem Cell Summit. Said Robin Young, stem cell industry analyst and host of the New York meeting: "The range and scope of stem cell therapeutic use in the United States grew much faster than we'd forecasted earlier this year. Virtually all of the increases we're seeing are for adult stem cell therapies and, in particular, the use by physicians of both allograft and autologous stem cell products. It would not be an exaggeration to call this unexpected and remarkable growth." Mr. Young's revised forecast of stem cell commercialization revenues for 2013-2020 will be presented at the February meeting in New York. The companies, scientists and physicians that are at the forefront of this remarkable increase in stem cell therapeutic use will be presenting at the 8th Annual New York Stem Cell Summit. Listed below is the preliminary lineup of presenters for the 8th Annual Stem Cell Summit. The Stem Cell Summit, an intensive one-day event, allows attendees to learn about the latest developments in the stem cell marketplace, … Continue reading

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Dr. Michael Har-Noy to Present at the Inaugural European Immunotherapy and Cancer Vaccine Congress in Brussels, Belgium

Posted: Published on November 27th, 2012

NEW YORK, NY--(Marketwire - Nov 27, 2012) - Immunovative, Inc. ("IMUN" or the "Company") ( OTCQB : IMUN ) announces today that Dr. Michael Har-Noy, founder and CEO of Immunovative Therapies, Ltd. ("ITL") was invited to speak at the inaugural Immunotherapies and Cancer Vaccine Congress to be held at the Sheraton Brussels Hotel on December 5-6 in Brussels, Belgium (the "Congress").Dr. Har-Noy will be joining industrial and academic leaders in immunotherapy and cancer vaccine development to discuss the latest ideas on how to maximize the immune response to cancer, optimize the clinical development timelines of immunotherapy drugs and boost the commercial success of immunotherapies. The recent FDA approvals of Dendreon's Provenge cancer vaccine for prostate cancer and Bristol Myers Squibb's Yervoy immunotherapy drug for melanoma has sparked a resurgence of interest in immunotherapies and cancer vaccines.The organizer of the Congress, Informa Life Sciences, predicts that by 2014 that 3 of the top 10 cancer drugs will be immunotherapy drugs.Major pharmaceutical companies are launching immunotherapy drug development programs to enter this lucrative market and many of the leading companies are making presentations at the Congress.A full program can be viewed on-line at: http://www.informa-ls.com/appdata/downloads/CQ3486_Immunotherapies_VIP_TT37.pdf Dr. Har-Noy will be speaking at the Novel … Continue reading

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InPlay from Briefing.com

Posted: Published on November 27th, 2012

5:25 pm Robbins & Myers certifies substantial compliance with second request in connection with NOV merger (RBN) Co announced that it and National Oilwell Varco (NOV) have certified substantial compliance with the U.S. Department of Justice's request for information (commonly called a "second request") pursuant to the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended ("HSR Act"), in connection with the proposed merger transaction in which National Oilwell Varco, Inc. would acquire all of the outstanding shares of Robbins & Myers for $60.00 per share in cash. Pursuant to the HSR Act, the premerger waiting period will expire at 11:59 p.m., Eastern Time, on December 27, 2012 (which is thirty days after the certification of substantial compliance), absent a challenge by the U.S. Department of Justice. Robbins & Myers also announced today that it is delaying its 2013 annual meeting of shareholders to March 26, 2013. 5:20 pm Zoltek misses by $0.01, misses on revs (ZOLT) Reports Q4 (Sep) earnings of $0.13 per share, $0.01 worse than the Capital IQ Consensus Estimate of $0.14; revenues rose 2.6% year/year to $44.2 mln vs the $46.67 mln consensus. 5:19 pm Medley Capital announces offering of 5 mln shares of common stock (MCC) … Continue reading

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Novelos Therapeutics To Present At The Benchmark 2012 Micro Cap Discovery Investor Conference On November 29

Posted: Published on November 27th, 2012

MADISON, Wis., Nov. 27, 2012 /PRNewswire/ --Novelos Therapeutics, Inc. (NVLT), a pharmaceutical company developing novel drugs for the treatment and diagnosis of cancer, today announced that Harry Palmin, President and CEO of Novelos, will present a corporate update at the Benchmark 2012 Micro Cap Discovery Investor Conference on Thursday, November 29, 2012. Mr. Palmin is scheduled to present at 10:00 a.m. CT. The conference will take place at the InterContinental Hotel in Milwaukee and is being sponsored by Benchmark Company, LLC. A live webcast of the Novelos presentation may be accessed via http://www.novelos.com The webcast will be archived for 90 days following the presentation. About Novelos Therapeutics, Inc.We are a pharmaceutical company developing novel drugs for the treatment and diagnosis of cancer. Our cancer-targeted compounds are selectively taken up and retained in cancer cells, including cancer stem cells, versus normal cells. Thus, our therapeutic compounds appear to directly kill cancer cells while minimizing harm to normal cells. This offers the potential for a paradigm shift in cancer therapy by providing efficacy versus all three major drivers of mortality in cancer: primary tumors, metastases and stem cell-based relapse. I-124-CLR1404 (LIGHT) is a small-molecule, broad-spectrum, cancer-targeted PET imaging agent. We believe LIGHT … Continue reading

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Unigene and Tarix Pharmaceuticals Enter Definitive Licensing Agreement for "Peptelligence-Engineered" TXA127

Posted: Published on November 27th, 2012

BOONTON, N.J. and CAMBRIDGE, Mass., Nov. 27, 2012 /PRNewswire/ -- Unigene Laboratories, Inc. (UGNE) and Tarix Pharmaceuticals today announced that the companies have entered into a definitive licensing agreement to develop an oral formulation of TXA127, Tarix's lead peptide drug candidate. The oral formulation of TXA127 is being developed jointly by Unigene and Tarix under a previously agreed upon feasibility program whereby the companies leveraged Unigene's Peptelligence technology platform to enable enhanced oral delivery of TXA127. According to terms of the licensing agreement, Tarix will have an exclusive worldwide license to Unigene's Peptelligence technology covering the use of that technology with Angiotensin (1-7), the pharmaceutical ingredient in TXA127, as well as its functional equivalents, analogues or derivatives. In return for the license, Tarix will pay Unigene a percentage of revenues, if any, derived from the direct sales of any oral dose form of an approved Angiotensin (1-7) product by Tarix or from any up-front, milestone or royalties received by Tarix from a third-party sub-licensee of Unigene's Peptelligence technology with respect to any Angiotensin (1-7) product. There is no upfront payment being made by Tarix to Unigene in connection with the execution of the license. Ashleigh Palmer, Unigene's Chief Executive Officer, … Continue reading

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HIV Vaccine Under Study May Last A Lifetime

Posted: Published on November 27th, 2012

A genetically-engineered HIV vaccine under study by Texas researchers works in a novel way. It targets specific cells exactly where the virus enters the body, stimulating them to generate an immune response so the virus can't take hold. If the strategy bears out, the vaccine will be a single dose and last a lifetime, says Marie-Claire Gauduin, PhD, assistant scientist at Texas Biomedical Research Institute. ''Many other HIV vaccines try to block the infection when the virus is already in," she says. "Here we try not to be infected to begin with," Gauduin tells Take Part. RELATED:Breakthrough: Early HIV Treatment Virtually Erases Risk of Passing Virus On About 33 million people worldwide are living with HIV/AIDS, according to estimates by the Joint United Nations Programme on HIV/AIDS. Most do not know it. The new vaccine, if perfected, could be given to children at puberty to stem this toll, Gauduin says. Most new cases of HIV infections worldwide are transmitted by sexual intercourse through outer layers of cells known as epithelial cells. These line the surfaces of structures throughout the body. The target of the new vaccine is the mucosal layers of the epithelium in the genital and rectal areas, where … Continue reading

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Seattle Genetics Receives FDA Orphan Drug Designation for ADCETRIS® (Brentuximab Vedotin) in Mycosis Fungoides

Posted: Published on November 27th, 2012

BOTHELL, Wash.--(BUSINESS WIRE)-- Seattle Genetics, Inc. (SGEN) announced today that ADCETRIS (brentuximab vedotin) has been granted orphan drug designation by the U.S. Food and Drug Administration (FDA) for the treatment of mycosis fungoides (MF). MF is the most common type of cutaneous T-cell lymphoma (CTCL). Seattle Genetics and its ADCETRIS collaborator, Millennium: The Takeda Oncology Company, are conducting the ALCANZA trial, a phase III clinical trial of ADCETRIS for patients with CD30-positive relapsed CTCL, including MF. ADCETRIS is not approved for the treatment of CTCL. This orphan drug designation is a part of our ADCETRIS regulatory strategy, designed to complement the Special Protocol Assessment for the ongoing ALCANZA study, said Clay B. Siegall, President and Chief Executive Officer of Seattle Genetics. The encouraging data from investigator-sponsored trials of ADCETRIS in CTCL, which will be presented at ASH, provide further support for our activities in this patient population. FDA orphan drug designation is intended to encourage companies to develop therapies for the treatment of diseases that affect fewer than 200,000 individuals in the United States. This designation provides Seattle Genetics with the opportunity for seven years of marketing exclusivity, grant funding to defray costs of clinical trial expenses, tax credits for … Continue reading

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Korean team develops new way of generating stem cells

Posted: Published on November 27th, 2012

Seoul (The Korea Herald/ANN) - Korean scientists have discovered a new molecular compound that could increase the efficiency of human adult cell reprogramming to induced pluripotent stem cells. The low-molecule Reprogramming Stimulating Compound 133, or RSC133, adds to the list of non-viral vectors that are crucial to advancing the biotechnology and production of iPS cells. Dr. Cho Yee-sook and Dr. Lee Jung-woon of the Korea Research Institute of Bioscience & Biotechnology led a team of researchers for this latest discovery that was published in Angewandte Chemie International journal early this month. It said that the compound derivative acts as the "booster of pluripotency," and it "potently improves the reprogramming of human somatic cells into a pluripotent state and aids the growth and maintenance of human pluripotent stem cells." Pluripotent stem cells, like embryonic stem cells, can be turned into any type of cell in the body. The biotechnology of iPS cells has been gaining recognition since Kyoto University professor Shinya Yamanaka discovered that they could be created from mature cells. He won the Nobel Prize in Medicine last month for his research. The reprogramming of adult cells to their immature state has the potential uses for patient-specific cures, such as … Continue reading

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Major Grants to Support Human Clinical Trials Advance Research Into Uses of Stem Cells From Cord and Placenta Tissue

Posted: Published on November 27th, 2012

Americord Registry Offers Exclusive Service Preserving Stem Cells From Cord Tissue and Placenta Tissue New York, NY (PRWEB) November 26, 2012 MSCs, which can easily be harvested from umbilical cord tissue and placenta tissue when a baby is born, are in fact currently the subject of over 200 clinical trials. While MSCs are not yet being used for medical therapies, research has indicated that they hold the promise of being able to someday treat debilitating conditions such as heart disease, type 1 diabetes, lung cancer, Parkinsons Disease, and injuries to bones and cartilage. Americord Registry offers the ability to preserve MSCs. We are committed to helping parents-to-be expand their babys options for future medical treatment, said Americord CEO Martin Smithmyer. Offering the option to preserve MSCs from umbilical cord tissue and placenta tissue is just one of the ways that we are pioneering best-in-class services in the cord blood industry. We are also working closely with scientists to develop a proprietary product that will significant increase the volume of stem cells that can be preserved when a baby is born. Americord Registry also offers the ability to preserve stem cells from umbilical cord blood. Parents-to-be can preserve stem cells from … Continue reading

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LifeMap Sciences, a Subsidiary of BioTime, Inc., Launches LifeMap Discovery™: A Database of Human Cellular Life for …

Posted: Published on November 27th, 2012

ALAMEDA, Calif.--(BUSINESS WIRE)-- LifeMap Sciences, Inc., a subsidiary of BioTime, Inc. (NYSE MKT: BTX), announced today the launch of LifeMap Discovery (discovery.lifemapsc.com), a state-of-the-art roadmap of embryonic development and stem cell biology. The platform integrates embryonic development and stem cell biology with molecular, cellular, anatomical, and disease-related information, and provides data-mining capabilities and bioinformatics applications. LifeMap Discovery is a unique and powerful tool for research and discovery in multiple disciplines, including stem cell biology, developmental biology, disease mechanisms and etiology, and drug and therapeutic discovery and development. This new and innovative database is a central element in LifeMaps discovery platform for biomedical and stem cell research, which also includes GeneCards, the leading human gene database, and MalaCards, the human disease database. The launch of LifeMap Discovery represents a key milestone for LifeMap Sciences. The platform is a central element in the generation of near-term revenues through paid subscriptions, and is expected to drive traffic to the recently launched LifeMap BioReagents marketing portal, as well as aid in the companys therapeutic discovery activities. Near-term subscription revenues from pharmaceutical and biotechnology companies Like GeneCards and MalaCards, LifeMap Sciences is making certain aspects of LifeMap Discovery free for use to stem cell researchers … Continue reading

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