A dietary supplement sold as a brain stimulant failed to help head trauma patients improve in function and thinking in a study, challenging the drugs use as a treatment option for the condition, researchers said. Patients with traumatic brain injury who were given the supplement, citicoline, scored similarly on function and cognition tests as those given a placebo, according to the study published today in the Journal of the American Medical Association. Previous animal research and pilot clinical studies had suggested the supplement might reduce cerebral injury caused by head trauma, stroke or aging. Citicoline, available as a supplement for more than a decade, is used mostly outside the U.S. for brain injury as well as in stroke and Alzheimers disease, said Ross Zafonte, the lead study author. Todays findings call into question the supplements use for head trauma, he said. We were disappointed to find that it did not appear to make a difference in outcome at 90 and 180 days post-injury, Zafonte, a professor and chairman of physical medicine and rehabilitation at Harvard Medical School in Boston and vice president of medical affairs at the Spaulding Rehabilitation Network, said in a Nov. 19 telephone interview. We are heartened … Continue reading
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