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NUI Galway to lead €6m research project into stem cell therapy for diabetes

Posted: Published on November 20th, 2012

The Irish Times - Monday, November 19, 2012 CLAIRE O'CONNELL Could a particular type of adult stem cell offer a useful therapy for diabetes? An EU-funded project being led by NUI Galway hopes to find out. The 6 million Reddstar project will assess whether the stem cells can tackle glucose levels and various complications of diabetes, including diabetic ulcers and eye, nerve, heart and kidney and bone damage. The approach centres on a specific adult stem-cell population owned by Orbsen Therapeutics, a spin-out from the Science Foundation Ireland-funded Regenerative Medicine Institute (Remedi) at NUI Galway. Initially, the project will develop ways to grow the bone-marrow-derived stem cells in a way that is useful for trials, according to company co-founder and Remedi director Prof Tim OBrien. The cells will then be tested in several preclinical models of diabetic complications at centres in Galway, Belfast, Munich, Berlin and Porto. Then the plan is to select one complication for which the adult stem cells will be assessed in human trials in Denmark. The three-year EU funding will support nine jobs in Ireland, five of which will be in Orbsen Therapeutics, according to CEO Brian Molloy, who says the project should help to build … Continue reading

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Noted Neurosurgeon Joseph Maroon, MD, FACS To Head Stemedica Medical & Scientific Advisory Board

Posted: Published on November 20th, 2012

Stemedica Cell Technologies, Inc., a leader in adult allogeneic stem cell manufacturing, research and development, announced today that Joseph C. Maroon, MD, FACS Neurosurgeon, Vice Chairman and Professor of the Department of Neurological Surgery at the University of Pittsburgh Medical Center (UPMC) has agreed to serve as Chairman of the Companys Medical and Scientific Advisory Board. Dr. Maroon is also the Heindl Scholar in Neuroscience at UPMC. San Diego, CA (PRWEB) November 19, 2012 Dr. Maroon is widely regarded as a premiere specialist in the surgical treatment of injuries and diseases of the brain and spine. His research into brain tumors, concussions and diseases of the spine have led to many innovative techniques for diagnosing and treating these disorders. He is the author of more than 250 peer-reviewed papers and 55 books or book chapters. Dr. Maroon commented, Stem cells are taking on an increasingly important role in the treatment of multiple neurological conditions. I have been impressed with Stemedicas credentials as a cGMP manufacturer of its proprietary lines of ischemic tolerant neural and mesenchymal stem cells that are licensed for use in clinical trials. These cells possess the important safety, potency, purity and immune-privileged characteristics that are needed in … Continue reading

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Stem Cell Pioneer Recognized for 20 Years of Discovery and Innovation

Posted: Published on November 20th, 2012

TUCSON, Ariz., Nov. 20, 2012 /PRNewswire/ -- Dr. David Harris, Professor of Immunology at the University of Arizona and a scientific pioneer in the field of stem cell banking, was the recipient of the Arizona BioIndustry Association (AZBIO) 2012 award for "20 Years of Discovery and Innovation". The annual AZBIO Awards is Arizona's premier bioscience event and was held at the Phoenix Convention Center. Dr. Harris is a graduate of Wake Forest University, the leading center for stem cell regenerative medicine and tissue engineering in the world today. In 1991, Dr. Harris became the first person to bank stem cells for future use. He did so by banking his first child's cord blood stem cells. In 1992, Dr. Harris founded the Arizona Cord Blood Bank which later evolved to become the Cord Blood Registry [CBR], the largest cord blood stem cell bank in the world. Dr. Harris continues as Chief Science Officer at CBR. In 2011, Dr. Harris founded AdiCyte, an adult stem cell banking company preserving adipose-derived [mesenchymal] stem cells for future use in regenerative medicine and tissue engineering. Adipose tissue, the medical name for 'fat', is the richest source of mesenchymal stem cells in the human body. "I … Continue reading

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Cancer: The stem cells that make cancer run riot. Kill them and you could destroy the disease…

Posted: Published on November 20th, 2012

By Steve Boggan PUBLISHED: 21:34 EST, 19 November 2012 | UPDATED: 21:34 EST, 19 November 2012 Professor Ian Mackenzie points to a little jumble of cells on a computer screen and smiles. Theyre cancer stem cells, he says. Not everyone in medicine believes in them yet, but look there they are. Even to the untrained eye, its clear there are two distinct types of cell; one that groups together a little like frogspawn, and another that looks like a slug. Stem cells, which are found in tissue all over the body, can grow into every kind of cell, including bone, skin and blood cells If you watched the slug-like one for long enough, youd see it move, says the professor. We believe this type of stem cell facilitates the spread of cancer and that the other is responsible for the growth of tumours and for making them return after you think your cancer has gone away. In Professor Mackenzies laboratory at Barts and the London Medical Schools Blizard Institute, researchers are busy extracting these cells from tumours. Their work represents a potentially extraordinary new approach to the disease. Read more: Cancer: The stem cells that make cancer run riot. Kill … Continue reading

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Pfizer Reports Top-Line Results Of A Phase 3 Study Evaluating Pregabalin Controlled-Release Formulation As Adjunctive …

Posted: Published on November 20th, 2012

NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE: PFE) today announced top-line results of a double-blind, placebo-controlled, Phase 3 study evaluating both the 165 mg dose and the 330 mg dose of pregabalin controlled-release (CR) formulation in adult patients with partial onset seizures with epilepsy. These study results indicate pregabalin CR did not meet its primary endpoint comparing the change in seizure frequency to placebo, although both doses were well-tolerated. This study is one of three Phase 3 studies of the pregabalin CR formulation, which will ascertain the potential use of pregabalin as a once-a-day therapy. The other two studies are evaluating the pregabalin CR formulation in fibromyalgia and post-herpetic neuralgia. Pfizer will continue to further analyze these top-line results as well as the top-line results of the other two studies. "While the study showed an observed improvement, it did not show a statistically significant difference in seizure frequency, which we believe may have been due to a higher-than-expected placebo response," said Steven J. Romano, M.D., senior vice president, head, Medicines Development Group, Global Primary Care Business Unit, Pfizer Inc. "Lyrica immediate-release has a proven success record in patients with epilepsy, and we look forward to understanding further the potential role of a … Continue reading

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‘About 70 p.c. of epilepsy cases are curable’

Posted: Published on November 20th, 2012

To mark National Epilepsy Day, Vikram Hospital organised a Harley Owners Group motorcycle rally here on Sunday. The rally, which was flagged off on the hospital premises on Millers Road, was taken out to the Bengaluru International Airport and back. The event aimed at creating awareness on epilepsy, especially breaking the stigma associated with the disease. Forty-five bikers participated in the rally, which was inaugurated by Deputy Chief Minister R. Ashok. Other guests included Director-General and Inspector-General of Police Lalrokhuma Pachau, the former Olympian swimmer Nisha Millet, former Miss India Rekha Hande and a team of neurologists and neurosurgeons of the hospital. This was a special ride because it was for a noble cause. We wanted to tell people that epilepsy can be cured in most cases with proper medication, said Sheeja Mathew, the only woman at the rally. Salamat Shariff, also a biker, said, It was good initiative by the hospital and the experience was great. Doctors at the rally said the advancement in the treatment for epilepsy had made it possible for those with condition to lead a normal life. Earlier, the patients were not issued driving licences and some were even denied admission to schools. This had … Continue reading

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Justin – Mission Possible – Portrait of Hope – Video

Posted: Published on November 20th, 2012

Justin - Mission Possible - Portrait of Hope Like us on Facebook at: facebook.com Here is the story of Center for Autism and Related Disorders (CARD) Justin. As he and his family battled and overcame an autism diagnosis. For more information about treatment for autism go to centerforautism.com DIAGNOSIS Autism AGE AT DIAGNOSIS: 2 BEGAN SERVICES WITH CARD: October 2005 ABA HOURS PER WEEK: 25 hours MAJOR MILESTONES: When his 60-minute tantrums became tantrums of only a few minutes. MAJOR ACHIEVEMENTS: Recovery from autism in June 12, 2006From:cardinc1990Views:5 0ratingsTime:03:57More inEducation Read more here: Justin - Mission Possible - Portrait of Hope - Video … Continue reading

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Riley – Mission Possible – Portrait of Hope – Video

Posted: Published on November 20th, 2012

Riley - Mission Possible - Portrait of Hope Like us on Facebook at: facebook.com/centerforautismandrelateddisorders Here is the story of Riley and how him and his family tackled a diagnosis of autism with the help of the Center for Autism and Related Disorders (CARD). For more information on treatment for autism go to centerforautism.com DIAGNOSIS: Autism AGE AT DIAGNOSIS: 3 BEGAN SERVICES WITH CARD: May 2008 ABA HOURS PER WEEK: 50 hoursFrom:cardinc1990Views:3 0ratingsTime:04:59More inPeople Blogs Read the original: Riley - Mission Possible - Portrait of Hope - Video … Continue reading

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Jack Riley and Nick – Mission Possible – Portrait of Hope – Video

Posted: Published on November 20th, 2012

Jack Riley and Nick - Mission Possible - Portrait of Hope Like us on Facebook at facebook.com/centerforautismandrelateddisorders Nick sits down with the parents of The A-Word's Jack Riley and talk his autism diagnosis and treatment with the Center for Autism and Related Disorders. For more information on treatment for autism go to centerforautism.com JACK RILEY'S portrait of hope DIAGNOSIS: Autism AGE AT DIAGNOSIS: 3 BEGAN SERVICES WITH CARD: April 2011 ABA HOURS PER WEEK: 25 hours MAJOR MILESTONES: During an early ABA session, Jack Riley's therapist was withholding markers from him until he identified which color he wanted to use (coloring was his favorite activity at the time, but he never had to EARN the opportunity to do it). He screamed and cried and ran away from the therapist, furious about not getting access to the markers. Then, in the midst of his tears and misery, he said it: "Boo" (Blue). Ahh yes, boo. We may be on to something here. MAJOR ACHIEVEMENTS: Becoming potty-trained, making friends, beginning to engage in a conversation with follow-up questions, learning to read and spell words and then Googling them to find related videos.From:cardinc1990Views:3 0ratingsTime:04:30More inPeople Blogs See more here: Jack … Continue reading

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Pray for my baby, mother pleads – Little Xyhir hospitalised with possible mild stroke

Posted: Published on November 20th, 2012

Stricken with grief, Kerry-Ann Ince is pleading for prayers for her baby. Little Xyhir Ince was admitted yesterday at the Bustamante Hospital for Children in St Andrew following what his doctor believes was a mild stroke. "This morning I was feeding him and the right side of his body went limp and he stopped talking," Kerry-Ann told The Gleaner. She immediately called his paediatrician who advised her to take him to the hospital because she suspected he had suffered a stroke. Three-year-old Xyhir is battling the rare condition, trilateral retinoblastoma and is in need of urgent medical treatment. He is not only completely blind with both eyeballs surgically removed, but he now has brain tumours, which are threatening his life and causing severe pain. One tumour is growing at a rapid rate out of his left eye socket on to the face, while another is growing at the base of his brain, wrapping itself around two main arteries. Xyhir is in need of critical radiotherapy, but the family has expended all its resources taking his treatment this far and is in need of immediate assistance to try to save his life. Since Xyhir's story was first published in The Sunday … Continue reading

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