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Studies On Stem Cell Therapy After Heart Attack Show Mixed Results

Posted: Published on November 10th, 2012

April Flowers for redOrbit.com Your Universe Online Conflicting studies were highlighted at this years American Heart Association Scientific Sessions meeting concerning stem cell therapy for heart attack patients. The first study, from the University of Louisville and Brigham and Womens Hospital, reported holy grail results for a Phase I clinical trial: marked sustained improvement in all patients with zero adverse effects. Roberto Bolli, M.D., of the University of Louisville and Piero Anversa, M.D., of Brigham and Womens Hospital presented data from their groundbreaking research in the use of autologous adult stem cells with patients who had previous heart attacks in a Late-Breaking Clinical Trial session. The researchers report that all patients receiving the stem cell therapy showed improved heart function after two years, with an overall 12.9 absolute unit increase in left ventricular ejection fraction (LVEF). LVEF is a standard measure of heart function that shows the amount of blood ejected from the left ventricle during a heartbeat. They saw no adverse effects from the therapy. In fact, nine patients showed evidence of myocardial regeneration new tissue replacing formerly dead tissue killed by heart attack in MRI scans. The trial shows the feasibility of isolating and expanding autologous stem cells … Continue reading →

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UPDATE on Stem Cell Therapy 7 November 2012

Posted: Published on November 10th, 2012

UPDATE on Stem Cell Therapy 7 November 2012 The Department of Health (DOH) saw the necessity to cover regulations for Stem Cell therapy. Stem Cell therapy belongs to the category of Advanced Cell therapy which includes biologics and blood. Many countries around the world apply a risk-based approach to assess the quality, efficacy and safety of advanced cell therapy. In many countries, Stem Cell is considered an investigational intervention. Stem Cell research employs both autologous (from same person) or allogenic (from another organism like animal or another human cell or tissue sample) method. Because there are many steps in the preparation of this lab and invasive procedure, there is therefore need to have a regulatory framework to protect Filipino citizens. Important questions were asked: is there proof of concept in animal trials where stem cell can then be applied in humans? Is there a way to ensure quality and purity of the raw materials? How safe is the procedure? How many did not benefit from the procedure? If this were investigational procedure, how will human subjects be protected? Sec. Enrique Ona convened a consultative working task force to provide recommendations on how to proceed in the early part of the … Continue reading →

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Teen prescription drug abuse on the rise – Video

Posted: Published on November 10th, 2012

Teen prescription drug abuse on the rise ALBANY -- "We're here to talk about prescription drug abuse and it is an epidemic problem," said Richard Hartunian, United States Attorney for the northern district of New York.Hartunian along with several local law enforcement agencies helped kick off a national campaign at a local level - Medicine Abuse Project.This coming Friday BOCES will be holding a webinar, which will educate students, parents and teachers on the dangers of prescription drug abuse."It's becoming a bigger concern it is readily accessible," Kimberly Aichner, St. Peter's Addiction Recovery Center.Aichner has experienced this problem not just in urban environments, but also in rural communities. "Addiction recovery center we know what to expect with the use of marijuana, we know what the signs and symptoms are," said Aircher.The problem is, these prescription drugs are in almost every medicine cabinet. "These prescription drugs they don't even know what they are taking half the time. They are just taking a pill that someone gives them. They don't even know what it is, what it's for and what kind of reaction they are going to have from it," said Aicher.Pain and ADHD medications are … Continue reading →

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Knoxville, Scott County to collect unwanted prescriptions Nov. 17

Posted: Published on November 10th, 2012

Knoxville man faces additional rape charges Knoxville man faces additional rape charges A Knoxville man had new rape charges filed against him on Friday.More >> A Knoxville man had new rape charges filed against him on Friday. The Knox County Sheriff's Department said two more victims came forward and alleged they were raped by 38-year-old Michael Reagan.More >> Local group needs funds to place wreaths on veterans' graves Local group needs funds to place wreaths on veterans' graves Wreaths Across America is a group of local volunteers who want to honor veterans this Christmasthey just do not have enough money.More >> Some local volunteers say they need help keeping up with an annual tradition of honoring local veterans.More >> Police arrest man in Nashville family's killing Police arrest man in Nashville family's killing Nashville police have arrested a man in the stabbing deaths of three family members in what police are saying were drug-related killings.More >> Nashville police have arrested a man in the stabbing deaths of three family members in what police are saying were drug-related killings.More >> Jury selected in Jackson for Vanessa Coleman trial Jury selected in Jackson for Vanessa Coleman trial Jurors were selected Friday in … Continue reading →

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Considerable added benefit of ipilimumab in advanced melanoma, study suggests

Posted: Published on November 10th, 2012

ScienceDaily (Nov. 9, 2012) The humanized antibody ipilimumab (trade name Yervoy) has been approved since August 2011 for the treatment of adult patients with advanced melanoma (black skin cancer) who have already been treated. The term "advanced" means that the melanoma can no longer be removed by an operation or that metastases have formed. The German Institute for Quality and Efficiency in Health Care (IQWiG) has examined the added benefit of the drug pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG). According to the findings, the drug offers major advantages with respect to overall survival, but is accompanied by major potential harm in the form of side effects. The overall conclusion is that ipilimumab offers considerable added benefit. "Best supportive care" as appropriate comparator therapy As specified by the Federal Joint Committee (G-BA), ipilimumab was to be compared with so-called "best supportive care." This means the best possible supportive therapy, optimized for the individual patient, which guarantees alleviation of the symptoms and improvement in the quality of life. The only study relevant to this benefit assessment compared ipilimumab in combination with "best supportive care" with "best supportive care" alone. This study was informative (randomized … Continue reading →

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Considerable added benefit of ipilimumab in advanced melanoma

Posted: Published on November 10th, 2012

Public release date: 9-Nov-2012 [ | E-mail | Share ] Contact: Dr. Anna-Sabine Ernst presse@iqwig.de 0049-022-135-6856 Institute for Quality and Efficiency in Health Care The humanized antibody ipilimumab (trade name Yervoy) has been approved since August 2011 for the treatment of adult patients with advanced melanoma (black skin cancer) who have already been treated. The term "advanced" means that the melanoma can no longer be removed by an operation or that metastases have formed. The German Institute for Quality and Efficiency in Health Care (IQWiG) has examined the added benefit of the drug pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG). According to the findings, the drug offers major advantages with respect to overall survival, but is accompanied by major potential harm in the form of side effects. The overall conclusion is that ipilimumab offers considerable added benefit. "Best supportive care" as appropriate comparator therapy As specified by the Federal Joint Committee (G-BA), ipilimumab was to be compared with so-called "best supportive care". This means the best possible supportive therapy, optimized for the individual patient, which guarantees alleviation of the symptoms and improvement in the quality of life. The only study relevant to this … Continue reading →

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US Drug Watchdog Now Urges Women Who Used Yaz Yasmin Birth Control Pills And Had A Heart Attack Or Stroke To Call The …

Posted: Published on November 10th, 2012

According to the US Drug Watchdog, We have a big problem-hardly anyone has heard about possible severe side effects associated with Yaz, Yasmin, or the generic version Ocella birth control pills. We even have a bigger problem--a very poorly publicized settlement might be near for users, who suffered a heart attack, a stroke, or a pulmonary embolism, blood clots, so we are urging victims to call the Johnson Law Group directly-before time runs out." As a background, in September of 2009, the US FDA released a warning letter sent to Bayer Pharmaceuticals over Yaz & Yasmin. The letter indicates that the drug maker hid out-of-specification test results for key ingredients in the birth control pills, and said that several batches of the drugs should have never been released to the public. The US Drug Watchdog says, "If you, or a friend were using birth control pills called Yaz, Yasmin, or their generic version Ocella, and severe side effects have occurred, such a pulmonary embolism, a heart attack, a stroke, or other severe medical conditions please contact the Johnson Law Group at 1-800-624-8899." http://www.johnsonlawgroup.com/ (PRWEB) November 09, 2012 Possible Side Effects Yaz/Yasmin The US Drug Watchdog says, "One of the biggest … Continue reading →

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BINGE DRINKING – Video

Posted: Published on November 10th, 2012

BINGE DRINKING A new study has found teenagers who binge drink are more likely to develop alcoholism or drug-dependency later in life.From:TenQueenslandNewsViews:9 0ratingsTime:01:51More inNews Politics Excerpt from: BINGE DRINKING - Video … Continue reading →

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HSBC Bank Hit By Huge Drug and Gun Scandal

Posted: Published on November 10th, 2012

You are here HSBC Bank Hit By Huge Drug and Gun Scandal Britain's biggest bank HSBC has come under fire for allegedly opening offshore accounts for a list of high-profile criminals including drug and gun dealers. Claims that criminals have laundered the money are under a major HM & Revenue investigation after the tax authority received the information from a whistleblower. The list identified 4,388 people holding 699m in offshore current accounts, the Daily Telegraph reports. It is unknown whether the bank had reported the suspicious accounts to HMRC. We can confirm we have received the data and we are studying it. We receive information from a very wide range of sources which we use to ensure the tax rules are being respected," HMRC said. Clamping down on those who try to cheat the system through evading taxes and over-claiming benefits is a top priority for us, and we value the information we receive from the public and business community. The account holders are reportedly in Jersey, a British dependency off the coast of France which has its own currency and tax laws and a major offshore financial centre. Some of the criminals involved are believed to be Daniel Bayes, … Continue reading →

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Chromadex, the potential "Game Changer" in Patient Dependency of the Multi-Billion Dollar Pharmaceutical Industry

Posted: Published on November 10th, 2012

CHICAGO, Nov. 8, 2012 /PRNewswire/ - Imagine a world where organic vitamins and dietary supplements prevented the use of engineered medication. Where patients could naturally treat medical problems without adhering to the many various side effects of pharmaceutical drugs. This is a notion that could appeal to the millions of Americans dealing with the defects of routine prescription drug consumption. Natural compounds such as pterostilbene and resveratrol have been tested to assist in treating ailing conditions such as high blood pressure and high cholesterol. Chromadex is a natural product company that examines these organic compounds in order to discover any medical use for them. Once they do, they create a patent on how to manufacture the compound with obtaining the rights of both the health claims and the patent itself.These ingredients are sold under the dietary supplement category through retail and other traditional marketing outlets. The 13-year old company has already tested thousands of products, creating over a dozen patents marketed across the world. Its most recent branded patent, pTeroPure derives from pterostilbene, an organic antioxidant compound found in blueberries. So far, pTeroPure has shown breakthrough potential for Chromadex. A clinical study conducted by the University of Mississippi Medical Center … Continue reading →

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