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Stroke Patients May Have a New Treatment

Posted: Published on October 10th, 2012

http://ad.doubleclick.net/adi/thirdage.oao/health_wellness/heart_health;pos=1;dcopt=ist;sz=728x90;KW=null;tile=1;ord= Possible New Treatment for Stroke Patients Researchers have identified a possible way to minimize brain-tissue damage in patients who have suffered a stroke and undergone surgery for the condition. A study conducted at the University of Calgarys Hotchkiss Brain Center found that the drug NA-1 seems to be safe for use in humans. Until now, the substance has been tested solely on animals. In the study, 92 patients were given the drug, while 93 patients got a placebo. The participants were given brain MRI scans three days after they began to take NA-1, as well as a 30-day followup assessment. The researchers said that they patients who were given the drug had fewer lesions (negative changes in brain tissue) than those who got the placebo. The researchers stressed that NA-1 isnt effective in all cases of stroke. Researcher Michael Hill said that the study suggests that intravenous infusion of NA-1 reduces tissue damage in patients who suffer a small stroke after an operation to repair a brain aneurysm. Further studies were needed, he said. The findings were published in the journal The Lancet. Copyright 1997 - 2012 ThirdAge Media, LLC. All rights reserved. Originally posted here: Stroke Patients May … Continue reading →

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InVivo Therapeutics Awarded $2 Million Loan from MassDevelopment

Posted: Published on October 10th, 2012

CAMBRIDGE, Mass. & BOSTON--(BUSINESS WIRE)-- InVivo Therapeutics Holdings Corp. (NVIV), and MassDevelopment announced today that MassDevelopment has awarded InVivo Therapeutics a $2 million loan from its Emerging Technology Fund to help fund the commercialization of InVivo's groundbreaking technologies for the treatment of spinal cord injuries (SCI) and other neurotrauma conditions. InVivo will use the proceeds from this low cost, seven year term loan for general working capital purposes and to purchase equipment for the expansion of manufacturing and research capabilities at its new facility in Cambridge MA. As InVivo's business grows, the Company expects to substantially increase employment in manufacturing, sales, marketing, clinical, and regulatory positions over the next two years. Through its 10-year, $1 billion Life Sciences Initiative, the Patrick-Murray Administration has nurtured our life sciences industry in Massachusetts into a world-leader and a key part of our economic recovery, said Greg Bialecki, the Secretary of Housing and Economic Development and MassDevelopment Board Chair. Continuing to support our innovation economy is a leading focus in the Administrations long-term economic development plan, and we applaud MassDevelopments financing of a vibrant, growing business in Massachusetts. InVivos treatment of spinal cord injuries typifies the Commonwealths highly innovative life sciences companies, said MassDevelopment … Continue reading →

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Acorda Therapeutics Names Jane Wasman President, International

Posted: Published on October 10th, 2012

ARDSLEY, N.Y.--(BUSINESS WIRE)-- Acorda Therapeutics, Inc. (ACOR) today announced that it has named Jane Wasman as President, International. Ms. Wasman most recently has served as Acordas Chief, Strategic Development and General Counsel. In her new role, Ms. Wasman will lead the Companys efforts to identify and launch in-licensing and commercial opportunities outside the United States. She will also be responsible for managing Acordas collaboration with Biogen Idec (BIIB) in their international development and commercialization of FAMPYRA (prolonged-release fampridine tablets). Ms. Wasman will also continue to lead the Companys global strategic development and will retain the title of General Counsel and Corporate Secretary. I am delighted that Jane will be spearheading our proactive efforts to ready Acorda for expansion into international markets. Janes career has included extensive international pharmaceuticals experience, in addition to her leadership of numerous key initiatives at Acorda. These will be valuable assets as we prepare for international expansion, said Ron Cohen, Acordas President and CEO. We believe that identifying opportunities outside the United States, as well as determining how to best realize the value of our existing pipeline and future in-licensed compounds in international markets, can contribute importantly to shareholder value. The Companys initial international efforts will … Continue reading →

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Biological mechanism that plays key role in early-onset dementia identified

Posted: Published on October 10th, 2012

ScienceDaily (Oct. 8, 2012) Using animal models, scientists at the Gladstone Institutes have discovered how a protein deficiency may be linked to frontotemporal dementia (FTD) -- a form of early-onset dementia that is similar to Alzheimer's disease. These results lay the foundation for therapies that one day may benefit those who suffer from this and related diseases that wreak havoc on the brain. As its name implies, FTD is a fatal disease that destroys cells, or neurons, that comprise the frontal and temporal lobes of the brain -- as opposed to Alzheimer's which mainly affects brain's memory centers in the hippocampus. Early symptoms of FTD include personality changes, such as increased erratic or compulsive behavior. Patients later experience difficulties speaking and reading, and often suffer from long-term memory loss. FTD is usually diagnosed between the ages of 40 and 65, with death occurring within 2 to 10 years after diagnosis. No drug exists to slow, halt or reverse the progression of FTD. A new study led by Gladstone Senior Investigator Robert V. Farese, Jr., MD, offers new hope in the fight against this and other related conditions. In the latest issue of the Journal of Clinical Investigation, available today online, … Continue reading →

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Kessler Foundation scientists present rehabilitation research findings at 2012 ACRM-ASNR Conference

Posted: Published on October 10th, 2012

Public release date: 8-Oct-2012 [ | E-mail | Share ] Contact: Carolann Murphy CMurphy@KesslerFoundation.org 973-324-8382 Kessler Foundation West Orange, NJ. October 8, 2012. Scientists from Kessler Foundation are presenting recent findings during Progress in Rehabilitation Research, the 2012 Conference of the American Congress of Rehabilitation Medicine and the American Society of NeuroRehabilitation (ACRM-ASNR). A.M. Barrett, MD, Amanda Botticello, PhD, Peii Chen, PhD, Abhijit Das, MD, Gail F. Forrest, PhD, Yael Goverover, PhD, Denise Krch, PhD, Karen Nolan, PhD, and Mooyeon Oh-Park, MD, are addressing a variety of topics that represent the Foundation's rehabilitation research in stroke, brain injury, multiple sclerosis and spinal cord injury. A.M. Barrett, MD, the current president of ASNR, is director of Stroke Rehabilitation Research at Kessler Foundation. Drs. Barrett and Chen will present promising results of prism adaptation treatment for spatial neglect, a common post-stroke hidden disability. Dr. Park, the assistant director of Stroke Rehabilitation Research, will present the Foundation's work on the impact of post-stroke cognitive deficits on patient satisfaction surveys of inpatient rehabilitation. Dr. Chen, research scientist in Stroke Rehabilitation Research, will discuss the Kessler Foundation Neglect Assessment Process (KF-NAP)-a new standardized tool for reliable functional assessment evaluation of spatial neglect. Drs. Chen and … Continue reading →

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Kids and brain injury: what you need to know to prevent long-term damage

Posted: Published on October 10th, 2012

by Michael Pines, Accident & Injury Prevention Expert Kids and brain injury: now that the school season has begun, learn what you can do to prevent brain injury for your little one. When people talk about traumatic brain injury, many assume its the type of injury reserved for professional athletes or those who serve our country. But the truth is, brain injury can happen to anyone, and when it does, lives can be changed forever. When children get injured, not only does the risk for permanent disability skyrocket, but the severity of the injury can increase substantially. Fortunately, most people who sustain a TBI including children will recover from the incident within a few days or weeks. Some mild brain injuries can heal with proper medical care. However, some brain injuries even mild concussions can lead to long-term damage. Now, researchers at The American Academy of Neurology are determining how brain injury affects children and how repetitive TBIs or even one severe blow to the head can lead to a neurodegenerative disease called chronic traumatic encephalopathy (CTE). CTE is a type of brain injury that can leave an injured person with irreparable brain atrophy similar to Alzheimers disease. Essentially, repetitive … Continue reading →

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New study on menopause drugs stokes fresh debate over cancer risk

Posted: Published on October 10th, 2012

By: Agence France-Presse October 10, 2012 7:03 AM OTHER SPECIAL FEATURES STORIES InterAksyon.com The online news portal of TV5 PARIS - Women who start hormone replacement therapy (HRT) soon after menopause do not show higher cancer incidence within 16 years, according to a Danish study published on Tuesday that fuels scientific discord over the treatment's safety. Indeed, women who took HRT in the investigation had a significantly lower risk of dying or developing heart problems, the researchers wrote in a paper published on the medical websitebmj.com. The new study was hailed by a menopause awareness group but a researcher who led a wider probe into HRT said it was worryingly underpowered. HRT has been shrouded in controversy since a Women's Health Initiative (WHI) study in 2002 reported a higher risk of breast cancer for women who take it, a finding echoed by the Million Women Study (MWS) a year later. "We found a significantly decreased risk of... death, heart failure or myocardial infarction (heart attack) when hormone replacement therapy was started early in postmenopause," wrote the Danish team. "(T)his finding was not associated with an increased risk of cancer, stroke, deep vein thrombosis, or pulmonary embolism." The MWS stirred up … Continue reading →

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Doctors call for new guidelines as study finds HRT 'is safe – and can protect heart'

Posted: Published on October 10th, 2012

By Jenny Hope PUBLISHED: 17:32 EST, 9 October 2012 | UPDATED: 18:32 EST, 9 October 2012 Taking HRT is safe and can protect against heart disease without increasing cancer risks, a milestone study claims. It found women who take hormone replacement therapy at the start of the menopause for 10 years can reduce their risk of heart failure, heart attacks and premature death. Most importantly, the study found there was no extra risk of cancer, strokes or blood clots even 16 years after starting HRT. HRT use dropped dramatically in 2002 when a study found women who took it were at a higher risk of breast cancer, heart disease and strokes. A new review has called that research 'unreliable and defective' Using HRT halved the risk of heart disease and strokes, and cut the death rate by 43 per cent during the study period. Experts hailed the findings as finally demonstrating that HRT has long-term health benefits after a decade-long controversy over its safety. British doctors are calling for rules on HRT prescribing to be re-written, allowing a new generation of women to get bone protection and relief from menopausal symptoms such as hot flushes and mood changes. Read the … Continue reading →

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Menopause drugs: Study stokes new debate over cancer risk

Posted: Published on October 10th, 2012

Women who start hormone replacement therapy (HRT) soon after menopause do not show higher cancer incidence within 16 years, according to a Danish study published on Tuesday that fuels scientific discord over the treatment's safety. Indeed, women who took HRT in the investigation had a significantly lower risk of dying or developing heart problems, the researchers wrote in a paper published on the medical website bmj.com. The new study was hailed by a menopause awareness group but a researcher who led a wider probe into HRT said it was worryingly underpowered. HRT has been shrouded in controversy since a Women's Health Initiative (WHI) study in 2002 reported a higher risk of breast cancer for women who take it, a finding echoed by the Million Women Study (MWS) a year later. "We found a significantly decreased risk of... death, heart failure or myocardial infarction (heart attack) when hormone replacement therapy was started early in postmenopause," wrote the Danish team. "(...) (T)his finding was not associated with an increased risk of cancer, stroke, deep vein thrombosis, or pulmonary embolism." The MWS stirred up a storm when it claimed HRT boosted cancer risk by between 30 and 100 percent, a finding criticised by … Continue reading →

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Attorney General Concerned About HRC Medical’s Former Patients

Posted: Published on October 10th, 2012

By Jennifer KrausConsumer Investigator NASHVILLE, Tenn.- The state Attorney General said he's prepared to contact every patient in Tennessee who got hormone replacement therapy from Nashville-based HRC Medical. This comes as the Attorney General has gone to court to shut down the entire company and after NewsChannel 5 Investigates first exposed problems with HRC's hormone therapy nearly a year ago. The Attorney General is so concerned that he wants every patient who went to the HRC clinic here in Nashville and those in Memphis and Knoxville to talk with their primary care physicians about the possible long term health problems they could face including endometrial cancer and breast cancer. Read the lawsuit filed against HRC Medical Former HRC patient Susan Moerschel told NewsChannel 5 Investigates, "It's frightening." Moerschel, who underwent hormone replacement therapy at HRC for a year, was stunned to hear now that the state attorney general has gone to court to shut down HRC Medical in order to "protect consumers." The 160-page complaint filed Monday accuses HRC and its owners of running the company in a "persistently fraudulent manner" and repeatedly making "false and misleading statements" about its heavily promoted hormone replacement therapy. The complaint also confirmed what … Continue reading →

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