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MS patients in B.C. part of trial on experimental treatment

Posted: Published on September 29th, 2012

TORONTO Multiple sclerosis patients in B.C. will be part of a federal government trial of a controversial experimental treatment. Researchers will begin recruiting patients Nov. 1 to study the treatment for chronic cerebrospinal venous insufficiency, or CCSVI, Health Minister Leona Aglukkaq said Friday. That treatment involves unblocking neck veins that Italian vascular surgeon Paolo Zamboni has suggested could be a cause of MS. About 100 patients are expected to take part in the trial to be conducted in B.C. and Quebec. Vancouver MS researcher Dr. Anthony Traboulsee will head the $6-million study being funded by Ottawa, the MS Society of Canada and the provinces where the trial will take place. Traboulsee said researchers will monitor MS patients over a two-year period in order to obtain scientific evidence on the safety and efficacy of the CCSVI procedure. Copyright (c) Go here to read the rest: MS patients in B.C. part of trial on experimental treatment … Continue reading

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Study into 'liberation treatment' for MS wins approval

Posted: Published on September 29th, 2012

CTVNews.ca Staff Published Friday, Sep. 28, 2012 10:51AM EDT Last Updated Saturday, Sep. 29, 2012 10:14AM EDT A Canadian study that will test the so-called liberation treatment on people with multiple sclerosis has received the necessary medical and ethical approvals to go ahead. Dr. Anthony Traboulsee, medical director of the UBC Hospital MS Clinic, and his team received ethics approvals from institutions in British Columbia and Qubec and will now begin the process to begin a clinical trial into the procedure. The main objective of the study will be to determine the safety of conducting angioplasty to open neck and chest veins, and to monitor how the procedure affects MS patients. This pan Canadian controlled study will allow us to monitor MS patients over a two-year period and obtain scientific evidence on the safety and efficacy of the CCSVI procedure in the long term, Dr. Traboulsee said in a statement Friday. Patient recruitment for the study will begin on Nov. 1, 2012. Approximately 100 patients are expected to participate in the trial, to be conducted in British Columbia and Qubec. The study is a collaborative effort of the Canadian Institutes of Health Research (CIHR), the MS Society of Canada and … Continue reading

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Canadian patient trial announced for controversial MS treatment

Posted: Published on September 29th, 2012

A long-awaited Canadian trial of a controversial experimental treatment for multiple sclerosis has been given the go-ahead and will soon begin recruiting patients, Health Minister Leona Aglukkaq announced Friday. Ms. Aglukkaq, in Halifax for a meeting with provincial and territorial health ministers, said about 100 MS patients will be enrolled in the trial to assess the safety and efficacy of the procedure to unblock narrowed neck veins. The condition dubbed chronic cerebrospinal venous insufficiency, or CCSVI has been proposed as a possible cause of MS by Italian vascular surgeon Paolo Zamboni. More than three years ago, Dr. Zamboni hypothesized that narrowed and twisted veins in the neck and chest prevent blood from draining properly from the brain, resulting in iron deposits that could cause the brain lesions typical of MS. The disease causes the destruction of myelin, the protective sheath around nerves throughout the body, leading to progressive physical and cognitive disability. Dr. Anthony Traboulsee, medical director of the UBC Hospital MS Clinic, will lead the $6-million study, which will be conducted initially in Vancouver and Montreal. Medical and ethical approval is also being sought for parts of the trial to be conducted in Quebec City and Winnipeg, Dr. Traboulsee … Continue reading

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Province won't sponsor trials for MS treatment, joining national study

Posted: Published on September 29th, 2012

WINNIPEG There will be no Manitoba-sponsored clinical trials into a new treatment for multiple sclerosis, but Health Minister Theresa Oswald says MS sufferers should not despair. The province is close to negotiating an arrangement with a Canadian group that would include Manitobans in a national study into the efficacy of the liberation treatment for MS, Oswald said Thursday. Earlier in the day, the Manitoba Health Research Council revealed that it had received only one application to conduct clinical trials for the new procedure and had found it wanting. A review committee examined the proposal and, based on the criteria that had been established, had just deemed that it was not good enough to go forward, said MHRC executive director Christina Weise. The research council recommended that Manitoba partner instead with MS clinical trials being organized by the Canadian Institutes of Health Research. Oswald said discussions with that group are already well underway. Im extremely optimistic that were going to be able to find a way for Manitobans to become part of the clinical study here in Canada, Oswald said from Halifax, where she was attending a meeting of provincial and territorial health ministers. Eighteen months ago, after considerable pressure from … Continue reading

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Cancer, induced pluripotent stem cell similarities

Posted: Published on September 29th, 2012

SACRAMENTO UC Davis investigators have found new evidence that a promising type of stem cell now being considered for a variety of disease therapies is very similar to the type of cells that give rise to cancer. The findings suggest that although the cells known as induced pluripotent stem cells (iPSCs) show substantial promise as a source of replacement cells and tissues to treat injuries, disease and chronic conditions, scientists and physicians must move cautiously with any clinical use because iPSCs could also cause malignant cancer. The article, "Induced pluripotency and oncogenic transformation are related processes," is now online in the journal Stem Cells and Development. "This is the first study that describes the specific molecular pathways that iPSCs and cancer cells share from a direct comparison" said Paul Knoepfler, associate professor of cell biology and human anatomy, and principal investigator of the study. "It means that much more study is required before iPSCs can be used clinically. However, our study adds to a growing knowledge base that not only will help make stem cell therapies safer, but also provide us with new understandings about the cancer-causing process and more effective ways to fight the disease." Since 2007, cell biologists … Continue reading

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New Genetic Snooping Technique Finds New Deadly Virus

Posted: Published on September 29th, 2012

September 28, 2012 Image Caption: A Metabiota field staff member collects blood samples from bushmeat in the Democratic Republic of Congo. Credit: Metabiota John Neumann for redOrbit.com Your Universe Online An intriguing new virus from the Democratic Republic of Congo (DRC) has been identified as the cause of a deadly outbreak of acute hemorrhagic fever, which killed two people and left one gravely ill in the summer of 2009. Described this week in the open-access journal PLoS Pathogens the new microbe has been named Bas-Congo virus (BASV) after the province in the southwest corner of the Congo where the three people lived. The virus was first discovered when a teenager, living in the rural village of Mangala in the DRC, suddenly fell ill and developed symptoms of a hemorrhagic fever, including bleeding from mucous membranes and blood in the vomit. This victim died within three days of the first signs of illness. A week later, a 13-year-old girl who attended the same school and lived in the same neighborhood came down with a similar illness and also died within three days, writes Nathan D. Wolfe, Joseph Fair, and Charles Chiu for National Geographic. Known viruses, such as Ebola, HIV and … Continue reading

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Cytori’s Stem Cell Therapy for Burns Wins U.S. Contract

Posted: Published on September 29th, 2012

By Ryan Flinn - 2012-09-28T20:12:41Z Cytori Therapeutics Inc. (CYTX), a biotechnology company with $10 million in annual revenue, rose the most in about a year after the company won a $4.7 million U.S. government contract to develop a stem cell therapy to treat burns caused by thermal or radioactive bombs. Cytori jumped 14 percent to $4.41 at the close in New York, the biggest single-day increase since October 2011. The shares of the San Diego-based company have doubled this year. Were seeing a lot of momentum, Chief Executive Officer Christopher Calhoun said today in an interview with Bloomberg Television. This contract is one more major thing that we are delivering on, and there is more to come. The two-year contract with the Department of Health and Human Services Biomedical Advanced Research and Development Authority may be worth $106 million over five years if certain milestones are met, Cytori said today in a statement. The company had a net loss last year of $32 million, according to data compiled by Bloomberg. Cytoris experimental therapy takes adipose tissue, or body fat, from a patient and through its device separates the adult stem and regenerative cells before transferring them to a burn wound. … Continue reading

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Power of the Dream Ventures Acquires Genetic Immunity

Posted: Published on September 29th, 2012

BUDAPEST, HUNGARY--(Marketwire - Sep 28, 2012) - Power of the Dream Ventures, Inc. ( OTCBB : PWRV ) is pleased to announce the acquisition of Genetic Immunity, Inc., a Phase III clinical stage biotechnology company with experimental nanomedicines that will lead to the next generation of immunotherapies, in a market that is projected to reach $11.00 billion by 2018. Genetic Immunity's lead product candidate is an immune boosting drug for HIV, which is now only treated by antiretroviral drugs that decrease the ability of the immune system to fight with the virus. DermaVir HIV-specific Immunotherapy is the first of a new line of curative nanomedicine products developed for the treatment and eradication of HIV. In addition, Genetic Immunity has implemented a Predictive Genomic Biomarker as companion diagnostics to accurately predict potential responder patients to DermaVir treatment. Such innovations towards personalized medicine increase the treatment effect and reduce the cost of pivotal trials in full compliance with the FDA's initiatives to improve products for patients (Driving Biomedical Innovation, 2011). In addition, following a successful DermaVir trial on HIV-infected adults, the US government is sponsoring a Phase II pediatric clinical trial. DermaVir is the first therapeutic vaccine that consistently boosts broadly directed … Continue reading

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Jamie Inglis undergoes pioneering stem cell treatment

Posted: Published on September 29th, 2012

Jamie Inglis undergoes pioneering stem cell treatment 10:06am Saturday 29th September 2012 in News By Kate Liptrot, kate.liptrot@thepress.co.uk Jamie Inglis smiles from his hospital bed in Germany JAMIE INGLIS would love to join the children in the colourful playroom on the other side of the hospital corridor. He would like to play with his new friend, Ryan, who he has painted a picture for and who has waved at him from the doorway but who wasnt allowed to come in. He would like to spend longer looking for spiders outside. Instead, to guard against possible infection and to stay near to medical treatment, the seven-year-old spends every day in the sunny bedroom that could belong to any boy if it wasnt for the drip, monitors and medical equipment standing alongside his Batman posters, bright paintings, action models and cuddly toys. Jamie has a little more freedom than a few weeks ago when, for a month, he was kept in isolation in a sealed room, which his parents had to be disinfected and wear gowns to enter. Now, as long as he puts on a mask and a hat to protect him from the cold, he is allowed to slowly pad … Continue reading

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Residents can get rid of unwanted prescriptions – Video

Posted: Published on September 29th, 2012

28-09-2012 18:08 This weekend, residents can get rid of unwanted prescription drugs before they fall into the wrong hands. The rest is here: Residents can get rid of unwanted prescriptions - Video … Continue reading

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