In countries such as South Africa, drugs commonly used to treat tuberculosis are becoming less effective as strains of the diseases develop resistance. Image: Tom Fox/Dallas Morning News/Corbis Showcasing more than fifty of the most provocative, original, and significant online essays from 2011, The Best Science Writing Online 2012 will change the way... Read More From Nature magazine More than 40% of tuberculosis infections that are resistant to front-line treatments are also resistant to some common backup drugs, according to research published this week in The Lancet1. Efforts to control tuberculosis are being hampered by the emergence of multidrug-resistant (MDR) strains of the disease, which resist treatment with two front-line antibiotics, rifampicin and isoniazid. In some parts of the world, as many as 50% of tuberculosis cases are resistant to these drugs2. Alternative treatment options are toxic and expensive, relying on second-line drugs that are not as effective and must be given in lengthy courses. Unfortunately, the majority of MDRtuberculosis cases occur in developing countries that cant afford the several billion dollars that the global Stop TB Partnershipestimates3 will be required to combat the disease. More recently, strains of tuberculosis have emerged that are resistant not only to front-line antibiotics, … Continue reading
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