Public release date: 2-Sep-2012 [ | E-mail | Share ] Contact: Robin Latham lathamr@nidcd.nih.gov 301-496-7243 NIH/National Institute on Deafness and Other Communication Disorders Scientists funded by the National Institutes of Health have restored the ability to smell in a mouse model of a human genetic disorder that causes congenital anosmiathe inability to smell from birth. The approach uses gene therapy to regrow cilia, cell structures that are essential for olfactory function. The study was funded by four parts of NIH: the National Institute on Deafness and Other Communications Disorders (NIDCD), the National Institute on Diabetes and Digestive and Kidney Diseases (NIDDK), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and the National Eye Institute (NEI). It was published online in the September 2, 2012, issue of the journal Nature Medicine. "These results could lead to one of the first therapeutic options for treating people with congenital anosmia," said James F. Battey, Jr., M.D., Ph.D., director of NIDCD. "They also set the stage for therapeutic approaches to treating diseases that involve cilia dysfunction in other organ systems, many of which can be fatal if left untreated." Olfactory dysfunction can be a symptom of a newly recognized … Continue reading →

Public release date: 2-Sep-2012 [ | E-mail | Share ] Contact: Emmanouil Dermitzakis emmanouil.dermitzakis@unige.ch 41-223-795-483 Universit de Genve Genetic disease risk differences between one individual and another are based on complex aetiology. Indeed, they may reflect differences in the genes themselves, or else differences at the heart of the regions involved in the regulation of these same genes. By gene regulation we mean the decision that the cell makes as to when, where and at what level to activate or suppress the expression of a gene. In theory, two people could thus share a gene that is perfectly identical and yet show differences in their predisposition to a disease due to genetic differences concerning the regulation (overexpression or underexpression) of this same gene. Numerous teams are currently trying to draw up a map of regions involved in gene regulation. Not an easy task, but invaluable since it allows us to understand all the genetic causes that can explain the predisposition to certain diseases. Working with twins Emmanouil Dermitzakis, Louis-Jeantet Professor at the Faculty of Medicine and member of the NCCR Frontiers in Genetics and the Institute of Genetics and Genomics of Geneva (IGE3), is a specialist in what is called … Continue reading →

YAHOO: Talent manager Annabelle Rama will fly to Germany in September to undergo therapy - stem cell therapy, that is. This has been a promise made by her son Richard Gutierrez who's footing the bill. "Early this year pa lang ay napagplanuhan na 'yung pagpapa-stem cell ng nanay ko at prinomise ko sa kanya na pag-iipunan ko, prinomise ko sa kanya na ako ang magti-treat sa kanya," Richard said on the first episode of "H.O.T. TV," Aug. 5. He noted, "'Yung mom ko hindi mahilig 'yan na pumunta sa mga doctor, hindi mahilig magpa-check-up." Looking forward This early, Annabelle is already excited about her trip and the upcoming treatment. "Kaya ako excited pumunta kasi unang-una mataas ang aking sugar, mataas ang aking cholesterol, tapos me problema pa ako sa high blood, blood pressure ko. Siguro nga kailangan kong pumunta ng Germany," she said, noting that the condition of her friends, talent manager Lolit Solis and actress Lorna Tolentino, have improved tremendously after going through stem cell therapy. "Nakita ko ang mukha ni Lolis pumuputi ang mukha niya, eh at saka mukha siyang fresh na fresh. Lalo na si LT, nakita ko rin siya. Mukhang gumanda naman siya. Basta lahat ng … Continue reading →

YAHOO: Talent manager Annabelle Rama will fly to Germany in September to undergo therapy - stem cell therapy, that is. This has been a promise made by her son Richard Gutierrez who's footing the bill. "Early this year pa lang ay napagplanuhan na 'yung pagpapa-stem cell ng nanay ko at prinomise ko sa kanya na pag-iipunan ko, prinomise ko sa kanya na ako ang magti-treat sa kanya," Richard said on the first episode of "H.O.T. TV," Aug. 5. He noted, "'Yung mom ko hindi mahilig 'yan na pumunta sa mga doctor, hindi mahilig magpa-check-up." Looking forward This early, Annabelle is already excited about her trip and the upcoming treatment. "Kaya ako excited pumunta kasi unang-una mataas ang aking sugar, mataas ang aking cholesterol, tapos me problema pa ako sa high blood, blood pressure ko. Siguro nga kailangan kong pumunta ng Germany," she said, noting that the condition of her friends, talent manager Lolit Solis and actress Lorna Tolentino, have improved tremendously after going through stem cell therapy. "Nakita ko ang mukha ni Lolis pumuputi ang mukha niya, eh at saka mukha siyang fresh na fresh. Lalo na si LT, nakita ko rin siya. Mukhang gumanda naman siya. Basta lahat ng … Continue reading →

PEP: Kahit pa noong kabataan niya ay kilala na si Lorna Tolentino bilang isa sa may pinakamagandang mukha sa Philippine showbiz industry. Hanggang ngayon na edad 50 na siya ay wala pa rin itong kupas. Ang kanyang sikreto ay nasa patuloy na pangangalaga niya sa katawan. Mahilig mag-ehersisyo si Lorna, at ilan sa regular niyang ginagawa ay ang yoga at gym workout. Nagda-diet din siya upang suportahan ang pag-e-exercise. Halos lahat na ng diet ay napagdaanan ko na, pero ang tamang paraan pa rin ay mag-ehersisyo ka at [kumain ng] tamang pagkain, saad ng aktres sa panayam ng PEP (Philippine Entertainment Portal), noong July 17 sa TV5 event sa Elements Centris, Quezon City. Ibig sabihin, meron pa ring caution akong ginagawa. Binabantayan ko rin kung ano yung kinakain ko kasi sabi nga nila, You are what you eat, e. Mas mapili ngayon si Lorna sa kanyang mga kinakain dahil na rin sa kanyang bad cholesterol level at hormonal imbalance sa katawan. Hindi siya kumakain ng anumang matataba at maalat na pagkain. Pagdating naman sa kanyang balat, Siyempre sa pangangalaga ng Flawless at Belo, at ni Joey Santos ng Villa Medica, kaya heto, patuloy na maganda yung skin ko. STEM CELL … Continue reading →