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Diet drugs could be scarce

Posted: Published on July 20th, 2012

FDA The Food and Drug Administration has approved two new diet drugs, but both have restrictions about who can -- or should -- take them. By Maggie Fox, NBC News The Food and Drug Administration has approved two new diet pills in a week -- the first new obesity drugs to be approved in 13 years. The agency, usually dry about its approvals, practically gushed about the pent-up demand for new obesity treatments in a country where more than two-thirds of the population is overweight or obese and steadily getting fatter. These prescription medications would be taken for the rest of a persons life, the FDA says on its website. For many people, obesity is a life-long condition, but we dont always think of it -- or treat it -- as such, said Dr. Amy Egan, deputy director for safety in FDAs Division of Metabolism and Endocrinology Products But dont expect to be able to get either drug easily.Each ofthe new drugs -- Belviq and Qsymia -- is being restricted in a different way. And consumer advocates say dieters should think twice about taking either. The FDA was so worried about Belviq, approved last week, that it has asked for … Continue reading →

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United Pharmacy Partners (UPPI) Signs Agreement with Novation for Low and High (PET) Energy Radioisotopes

Posted: Published on July 20th, 2012

SUWANEE, Ga.--(BUSINESS WIRE)-- United Pharmacy Partners (UPPI) is pleased to announce the signing of a 5-year agreement with Novation, a leading health care supply chain expertise and contracting company, to offer both low and high (PET) radiopharmaceuticals. UPPI radiopharmacies have the ability to supply a full scope of radiopharmaceutical products for both diagnostic and therapeutic uses to assist members in servicing their patients needs. Novation provides sourcing services, as well as information and data services to a broad range of healthcare providers in the United States. In addition to providing both low and high radioisotopes to the member sites served by Novation, UPPI will offer a host of support options to those members. UPPI will offer quality programs in the areas of Continuing Education and Reimbursement Support which can include hotline support, webinars, facility audits, Healthcare Reform Consulting and Accreditation assistance. BioDose Patient Management Systems, the exceptional, easy to use patient management system which allows the technologists to capture key patient data, manage patient studies, electronically order/fax doses plus many more tasks is also available to members. Perry Polsinelli, President of UPPI, stated We are excited about this radiopharmaceutical contract award and the opportunity to provide exceptional value, products, service … Continue reading →

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New studies show spinal cord injury and ALS respond to cell transplantation

Posted: Published on July 20th, 2012

Public release date: 18-Jul-2012 [ | E-mail | Share ] Contact: David Eve cellmedicinect@gmail.com Cell Transplantation Center of Excellence for Aging and Brain Repair Tampa, Fla. (July. 18 , 2012) Two studies published in a recent issue of Cell Medicine [2(2)] report on the therapeutic efficacy of stem cell transplantation in animal models of amyotrophic lateral sclerosis (ALS) and spinal cord injury (SCI). Cell Medicine is freely available on-line at http://www.ingentaconnect.com/content/cog/cm. Mensenchymal stem cell transplantation in spinal cord injured rats promotes functional recovery Transplantation of mesenchymal stem cells (MSCs), multipotent stem cells with the ability to differentiate into a variety of cell types with renewal capacities, has been found to enhance laboratory animal function after induced spinal cord injury. However, the biological mechanism of the functional enhancement has not been clearly defined. In an attempt to gain a clearer picture of the mechanism, a team of Korean researchers transplanted MSCs derived from human umbilical cord blood into the tail veins of laboratory rats immediately after spinal cord injury. The intravenous route was selected because the researchers felt that injection into the damaged site could further traumatize the injured spinal cord, although intravenously injected MSCs risk being eliminated by the host … Continue reading →

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Stem cell procurement plan gets ministry OK

Posted: Published on July 19th, 2012

A health ministry panel will allow cord blood banks to provide raw material to create induced pluripotent stem cells for regenerative medicine, a move that would boost the establishment of an "iPS Stock" system proposed by Kyoto University professor Shinya Yamanaka. Only cord blood not used in leukemia treatment would be provided to the iPS Stock for use in creating iPS cells, said the members of the panel under the Ministry of Health, Labor and Welfare. The details of conditions for the provision will be discussed by eight banks storing cord blood and Kyoto University, the members said. In a related move, Yamanaka said Tuesday he aims to team up with the Japanese Red Cross Society in the hope that by allowing scientists to tap into the society's data on human leukocyte antigen types, which can be compared with blood types for cells, the iPS Stock would be able to promptly procure the types of cells unlikely to be rejected by transplant recipients. Establishing the iPS Stock would help physicians to shorten the time and reduce the costs associated with procuring cells for transplant treatment. But as patients would be receiving other people's cells, it is necessary to work on … Continue reading →

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Phrixus Pharmaceuticals, Inc. Reports Positive Preclinical Results in Respiratory Disease in Duchenne Muscular …

Posted: Published on July 19th, 2012

ANN ARBOR, MI--(Marketwire -07/19/12)- Phrixus Pharmaceuticals, Inc., a specialty pharmaceutical company focused on innovative therapies for Duchenne muscular dystrophy (DMD) and heart failure, today announced that it has completed preclinical studies in mdx mice that demonstrate a beneficial effect of Carmeseal on the diaphragm, the skeletal muscle that supports respiration, after subcutaneous dosing as low as 3 mg/kg per day. Phrixus evaluated the effect of Carmeseal in mdx mice, the most widely used animal model of DMD, in a number of dosing regimens ranging from daily to weekly dosing, and at doses ranging from 3 to 300 mg/kg per day, all administered subcutaneously. Mice were aged to seven months and then dosed for five months to allow for full development of the phenotype. The effect of Carmeseal was evaluated by whole body plethsymography (WBP), an established method to understand the impact of drugs on respiratory function. These studies indicate that Carmeseal has a maximal effect on tidal volume, an important measure of respiratory performance, at doses as low as 3 mg/kg dosed once-a-day. This dosing would translate into a daily dose for each patient of 105 mg based on a 35 kg pediatric patient compared to bolus intravenous dosing of … Continue reading →

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Phrixus Pharmaceuticals, Inc. Announces Funding by DuchenneDashboard, Led by Coalition Duchenne, for Preclinical Studies

Posted: Published on July 19th, 2012

ANN ARBOR, MI--(Marketwire -07/19/12)- Phrixus Pharmaceuticals, Inc., a specialty pharmaceutical company focused on innovative therapies for Duchenne muscular dystrophy (DMD) and heart failure, today announced that it has received $67,374 in sponsored research funding from a number of DMD parent organization through the DuchenneDashboard. This funding will allow Phrixus to extend its recent finding that Carmeseal, its lead product candidate, can be delivered subcutaneously at very low dose to treat respiratory aspects of DMD to cardiac indications as well. Phrixus and its collaborators had previously demonstrated that Carmeseal is effective in preclinical cardiac models after intravenous delivery. "We are excited to be collaborating with Cath Jayasuriya, Founder and President of Coalition Duchenne, and the other parent organizations through the DuchenneDashboard. The Dashboard provides an optimal way for us to engage with parents and to fund this important development work," said Thomas A. Collet, president and CEO. The organizations that contributed through the DuchenneDashboard were: Coalition Duchenne, Hope for Gus, JB Keys, Jett Foundation, Michael's Cause, Ryan's Quest, Suneel's Light, Team Joseph, Two Smiles One Hope and the Zack Heger Foundation. DMD is the most devastating of the muscular dystrophies. No drug is approved for its treatment. It is a genetic … Continue reading →

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Ethics – Autism Therapy Video – Video

Posted: Published on July 19th, 2012

18-07-2012 13:34 Conflict of Interest - Definition & Dual-Role Relationships. Preview clip from Unit 15 in the series of Online ABA Training Center materials from Behavior Frontiers Excerpt from: Ethics - Autism Therapy Video - Video … Continue reading →

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School for autistic children opening in Boulder

Posted: Published on July 19th, 2012

A new autism treatment school is set to open in January, giving parents of autistic students another option. The Joshua School, which has been operating a 40-student school in Englewood for seven years, plans to rent space for a Boulder location at Shepherd of the Hills Lutheran Church, 7077 Harvest Road in Gunbarrel. The nonprofit school also has met its first fundraising goal for the new campus, raising $75,000. "Many of our kids come from the region around Boulder," said Jason Gruhl, executive director of The Joshua School. "This will allow kids to get services in their home community." He said the Boulder school, which is accepting applications, will serve about 16 students ages 6 to 21, expanding in future years based on the needs of families in northern Colorado. A preschool also is part of the expansion plans. While the school specializes in autism, it also serves students with other developmental disabilities. The school is authorized by the Colorado Department of Education to receive state and district funding. Most students who attend the school are placed there by school districts, which cover the cost of tuition. Parents also may decide to enroll a child and cover the tuition themselves. … Continue reading →

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Franklin Hosp. working hard to prevent strokes

Posted: Published on July 19th, 2012

Franklin Hospital is participating in the American Heart Association/American Stroke Association's Get With The Guidelines Stroke program. Emergency room director Shirley Spangler said the program's goal is to improve the overall quality of care for stroke patients by improving acute stroke treatment and preventing future strokes and cardiovascular events. Lee H. Schwamm, M.D. and chair of the Get With The Guidelines National Steering Committee and director of the TeleStroke and Acute Stroke Services at Massachusetts General Hospital in Boston commends the hospital for its commitment to implementing standards of care and protocols for treating stroke patients. "Get With The Guidelines Stroke was developed to help hospitals employ proven science-based treatment guidelines, including those developed by the American Stroke Association. The American Heart Association and Brain Attack Coalition are also involved. These guidelines address acute stroke management, primary prevention of cardiovascular diseases, secondary prevention of strokes and the establishment of primary stroke centers, he said. Spangler said as a program participant, Franklin Hospital is encouraged to develop a comprehensive system for providing rapid diagnosis and treatment of stroke when patients are admitted to the emergency department. "This includes being equipped to provide brain-imaging scans, making neurologists available to conduct patient evaluations … Continue reading →

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Study finds pregnancy and weed a dangerous mix

Posted: Published on July 19th, 2012

A study from Adelaide University has found smoking marijuana around the time of pregnancy more than doubles the chance of a premature birth. Researchers have released the results of a study into risk factors that affect a woman's likelihood of going into early labour - including smoking marijuana before conception. It is widely known that smoking cannabis during pregnancy increases the risk of giving birth before 37 weeks, but Professor Claire Roberts from Adelaide University's Robinson Institute says this study is the first to recognise that smoking the drug before conception also has an effect. "If you think about it, a pregnancy starts with an egg meeting a sperm and the quality or the health of your eggs is going to depend a lot on what you did prior to conception," she said. "Certainly other work that we're doing and that other groups are doing is showing that pre-conception is a very important time in determining outcome for pregnancy." Professor Roberts says women who smoke marijuana are also more likely to smoke cigarettes and that adds to the risk. "Women who smoke marijuana either prior to or during pregnancy may also do other risky behaviours, like maybe drink alcohol and … Continue reading →

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