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Child dead after suffering brain injury

Posted: Published on July 19th, 2012

BLOOMINGTON, Ind. (WISH) - At 2:30 a.m. Thursday, a child passed away after a suffering a brain injury. The child's mother and her girlfriend were arrested and are being preliminarily charged in connection to the death. Bloomington Police officers and detectives arrived to the 2300 block of S. Henderson St. at 8:19 p.m. Tuesday in response to a 2-year-old child who was having difficulty breathing. The child was transported to IU Health Bloomington Hospital where medical personnel found indications of possible child abuse, according to a report. Medical staff at the hospital told Bloomington Police that the child had a severe head injury and bruising from what appeared to be from older injuries. The child was transported to Riley Hospital for continued treatment. The childs mother, Tameria Kline, and the mothers girlfriend, Dominique Irby, were brought to the Bloomington Police Department for questioning. Irby admitted to officers that she had abused the child before in the part while the childs mother watched. Both the mother and the girlfriend denied abuse that caused the brain injury, officers say. Irby has been initially charged with battery on a minor, a Class D felony, and Kline has been charged with neglect of a … Continue reading →

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The Yin and Yang of stem cell quiescence and proliferation

Posted: Published on July 19th, 2012

A quiescent hematopoietic stem cell (white) engages in a molecular dialog with a preosteoblast (blue). The communication takes place via Flamingo (shown in red) and Frizzled (green), which are found at the interface between the two. Credit: Courtesy of Ryohichi Sugimura, Stowers Institute for Medical Research Not all adult stem cells are created equal. Some are busy regenerating worn out or damaged tissues, while their quieter brethren serve as a strategic back-up crew that only steps in when demand shoots up. Now, researchers at the Stowers Institute for Medical Research have identified an important molecular cue that keeps quiescent mouse hematopoietic (or blood-forming) stem cells from proliferating when their services are not needed. Publishing in the July 20, 2012 issue of Cell, the team led by Stowers Investigator Linheng Li, Ph.D., report that Flamingo and Frizzled 8, a tag team best known for its role in establishing cell polarity, are crucial for maintaining a quiescent reserve pool of hematopoietic stem cells in mouse bone marrow. Their finding adds new insight into the mechanism that controls the delicate balance between long-term maintenance of stem cells and the requirements of ongoing tissue maintenance and regeneration. "Hematopoietic stem cells daily produce billions of … Continue reading →

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Gene study raises hopes for colon cancer drugs

Posted: Published on July 19th, 2012

More than 200 researchers investigating colon cancer tumors have found genetic vulnerabilities that could lead to powerful new treatments. The hope is that drugs designed to strike these weak spots will eventually stop a cancer that is now almost inevitably fatal once it has spread. Scientists increasingly see cancer as a genetic disease defined not so much by where it starts -- colon, liver, brain, breast -- but by genetic aberrations that are its Achilles' heel. And with an understanding of which genetic changes make a cancer grow and thrive, they say they can figure out how best to mount an attack. They caution, however, that most of the drugs needed to target the colon cancer mutations have yet to be developed. The colon cancer study, published Wednesday, July 18, in Nature, is the first part of a sweeping effort that is expected to produce a flood of discoveries for a wide range of cancers. "There are so many different ways that you can attack this tumor type," said Raju Kucherlapati, the principal investigator for the colon cancer project and a professor of genetics and of medicine at Harvard Medical School. "We have an opportunity to completely change the landscape." … Continue reading →

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Colon cancer researchers find genetic vulnerabilities

Posted: Published on July 19th, 2012

More than 200 researchers investigating colon cancer tumors have found genetic vulnerabilities that could lead to powerful new treatments. The hope is that drugs designed to strike these weak spots will eventually stop a cancer that is now almost inevitably fatal once it has spread. Scientists increasingly see cancer as a genetic disease defined not so much by where it starts colon, liver, brain, breast but by genetic aberrations that are its Achilles' heel. And with a detailed understanding of which genetic changes make a cancer grow and thrive, they say they can figure out how best to mount an attack. They caution that most of the drugs needed to target the cancer mutations have yet to be developed. The colon cancer study, published Wednesday in Nature, is the first part of a sweeping effort that is expected to produce a flood of discoveries for a wide range of cancers. "There are so many different ways that you can attack this tumor type," said Raju Kucherlapati, the principal investigator for the colon cancer project and a professor of genetics and of medicine at Harvard Medical School. "We have an opportunity to completely change the landscape." Researchers have studied colon cancer … Continue reading →

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Painful Prescriptions: Dangerous consequences when pharmacists get it wrong

Posted: Published on July 19th, 2012

LOVELAND, OH (FOX 19) - Sitting at her kitchen table, Margaret Link recalls those strange months when she just didn't act like herself. "I would fall asleep at my desk," she said. She also remembers walking out in front of a car after work only to be rescued by her sister. There was also her son's out-of-town hockey weekend, much of which she spent sleeping in the hotel room. As soon as they checked-in, "I immediately went to bed and told him to go hang-out with the other parents and kids. And I just slept all the way until the next morning." Then one day, she showed-up at her pharmacy looking to re-fill her prescription for the allergy drug Claritin. This was back when doctors had to prescribe it. "And they looked-up my name and said that they didn't have me on Claritin," Link recalled. "I said, Well, that's what I've been taking.'" She called her son at home to get the prescription number off the bottle. "And they told me, That's not what we've been fillingWe've got you on a pill for your nerves, honey.'" People at the pharmacy told her that someone misread her doctor's prescription. Written in … Continue reading →

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hcgTreatments / Diet Doc Weight Loss Program Believed to be Safer and More Effective than FDA Approved Diet Pill Qsymia

Posted: Published on July 19th, 2012

Los Angeles, CA (PRWEB) July 19, 2012 The FDA announced on Monday night that Vivus Inc.s Qsymia, formerly known as Qnexa is now approved. Janet Woodcock, director of the FDAs Center for Drug Evaluation and Research states, obesity threatens the overall well being of patients and is a major public health concern. Qsymia, used responsibly in combination with a healthy lifestyle that includes a reduced-calorie diet and exercise, provides another treatment option for chronic weight management. The drug is only approved for people who are overweight or obese and have at least one weight-related health problem such as diabetes or high blood pressure and will also be prescribed a diet and exercise plan. According to a news release by the FDA, Qsymia is a combination of two FDA approved drugs, phentermine and topiramate. Phentermine is an amphetamine used for short-term weight loss and topiramate is indicated to treat certain types of seizures for those with epilepsy and is supposed to suppress the appetite. Phentermine is the phen half of the drug fen-Phen which was taken off the market in 1997 due to numerous lawsuits that claimed the drug caused heart valve damage and resulted in a $13 billion settlement. Results … Continue reading →

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Wonder Drug Provigil Does Have Side Effects

Posted: Published on July 19th, 2012

The wonder drug for sleep deprived patients, Provigil, is getting some good press. But a news report reveals there are some side effects and it's not known if long term use is harmful or not. The drug was intended for sufferers of sleep apnea, narcolepsy and other disorders, but has recently been prescribed for fatigue and patients complaining of lack of concentration. The boost most report, with no dependency difficulties, has caused doctors to prescribe the drug for people who want to increase their vigor and give them an edge in occupations like business and even piloting aircraft. At this point, most patients on Provigil, or its generic counterpart Modafinil, are reporting wondrous results with no addiction or withdrawal symptoms. But a news report by the Huffington Post shows there are reports of adverse side effects. These include headaches, nausea, back pain and tingling skin. Some have even reported rashes, problems with breathing, depression and even hallucinations. But the biggest worry is that the drug hasn't been tested for long-term problems and, since the drug is relatively new and not yet widely prescribed, there's no way of telling until time has gone by. By then it may be too late. … Continue reading →

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Qsymia, Belviq: New Weight Loss Drugs Compared

Posted: Published on July 19th, 2012

What You Need to Know About New Weight Loss Drugs Belviq and Qsymia July 18, 2012 -- Two new prescription weight loss drugs, Belviq and Qsymia, now have the FDA's blessing. Which, if either, is for you? Both drugs help some people lose weight. Neither drug is for everyone. Yet the two drugs are quite different. Here's WebMD's FAQ comparing Qsymia to Belviq. Vivus Pharmaceuticals says you should pronounce Qsymia this way: kyoo-sim-EE-uh. (The company's preferred name was Qnexa, but that was nixed by FDA as sounding too much like other drugs.) Arena Pharmaceuticals says you should pronounce Belviq this way: BEL-VEEK. Vivus says Qsymia should be available "in the fourth quarter of 2012," which begins in September. But don't look for it in your local pharmacy. Because women taking Qsymia must use birth control (see below) the drug will be sold only through "certified pharmacies." These are likely to be major online pharmacies. Because Belviq has a potential for abuse (see below), the U.S. Drug Enforcement Administration must rule on how to schedule the drug. That process probably began no later than last May. As this usually takes four to six months, Belviq should become available by early 2013. … Continue reading →

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Albany College of Pharmacy and Health Sciences to Offer Bachelor's Degree in Microbiology

Posted: Published on July 19th, 2012

ALBANY, NY--(Marketwire -07/18/12)- Albany College of Pharmacy and Health Sciences has received approval from the New York State Education Department to offer a bachelor's degree in Microbiology and plans to enroll the program's first class in fall 2013. The addition of the Microbiology program continues the academic expansion of the College over the past decade, which in addition to the doctor of pharmacy program, now includes five bachelor's programs and five graduate programs. Microbiology is the study of microscopic living organisms such as bacteria, fungi, and viruses. The curriculum for the program, which was developed in accordance with guidelines published by the American Society for Microbiology, includes coursework in subjects such as immunology, biochemistry, microbial physiology, and microbial genetics. To accommodate the needs of the program, the College plans to hire two new full time faculty and a part time instructor, in addition to renovating its existing microbiology lab. The B.S. in Microbiology will prepare graduates for employment or advanced study in fields requiring knowledge of microbial life, ranging from health care to medical equipment to public health. Specific career options may include: research laboratory technician, drug analyst, industrial microbiologist, public health administrator, public health biologist/epidemiologist, and biotechnologist. According to … Continue reading →

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Researchers identify mechanisms that allow embryonic stem cells to become any cell in the human body

Posted: Published on July 19th, 2012

(Phys.org) -- New research at the Hebrew University of Jerusalem sheds light on pluripotencythe ability of embryonic stem cells to renew themselves indefinitely and to differentiate into all types of mature cells. Solving this problem, which is a major challenge in modern biology, could expedite the use of embryonic stem cells in cell therapy and regenerative medicine. If scientists can replicate the mechanisms that make pluripotency possible, they could create cells in the laboratory which could be implanted in humans to cure diseases characterized by cell death, such as Alzheimer's, Parkinson's, diabetes and other degenerative diseases. To shed light on these processes, researchers in the lab of Dr. Eran Meshorer, in the Department of Genetics at the Hebrew Universitys Alexander Silberman Institute of Life Sciences, are combining molecular, microscopic and genomic approaches. Meshorer's team is focusing on epigenetic pathwayswhich cause biological changes without a corresponding change in the DNA sequencethat are specific to embryonic stem cells. The molecular basis for epigenetic mechanisms is chromatin, which is comprised of a cell's DNA and structural and regulatory proteins. In groundbreaking research performed by Shai Melcer, a PhD student in the Meshorer lab, the mechanisms which support an open chromatin conformation in embryonic … Continue reading →

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