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Eisai Enters Russian Market With Approval of First Product

Posted: Published on June 27th, 2012

Hatfield, England (ots/PRNewswire) - Zonegran(R) (zonisamide) set to offer new option for epilepsy treatment in Russia Eisai, one of the world's leading research-based pharmaceutical companies, announces the expansion of its operations into Russia, with the approval of its first product - the epilepsy treatment, Zonegran(R) (zonisamide). Eisai's entry into the Russian healthcare marketplace is part of the company's plan (HAYABUSA) to have a presence in the top 20 pharmaceutical market regions and make contributions to more than 500 million patients by 2015. The Russian pharmaceuticals market constitutes the 11th largest in the world and is expected to see high growth going forward.[1] Zonisamide is expected to be available across Russia as adjunctive therapy in the treatment of adult epilepsy patients with partial seizures, with or without secondary generalisation by the end of Eisai's financial year 2012 (30 March 2013). The availability of this therapy is significant as the successful treatment of partial-onset seizures (the most common type of epilepsy) remains a challenge. Although new to the Russian marketplace, zonisamide is an established anti-epileptic therapy and has been available in Europe since 2005. Of note is that recently the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) issued … Continue reading

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Autism can be diagnosed with a simple EEG test, says study

Posted: Published on June 27th, 2012

A simple EEG test may be all that is needed to find autism in children, says a new study. Researchers at Harvard Medical School and Boston Children's Hospital, in a study of 1000 children, were able to find patterns in brain activity in those who have autism, reported Fox News. An EEG test, or Electroencephalography, looks at electrical activity in the brain using electrodes that are fitted on to the scalp of the patient. Autism is difficult to detect and appears differently with varying severity in people. A common symptom is difficulty with social interaction. Read more on GlobalPost:3D printing - Your body parts made to order. According to Medical News Today, the study found that those children with autism had poor short range connectivity in the left hemisphere of the brain. They also found increased connectivity in other regions. BBC reported that researchers suspect that the brain's increased connectivity in some parts were compensating for reduced connectivity in other parts. The study may help diagnose autism earlier in life and even test whether treatment for the illness is working. View post: Autism can be diagnosed with a simple EEG test, says study … Continue reading

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Clot-busting medicine safe for use in warfarin-treated patients following stroke

Posted: Published on June 27th, 2012

Public release date: 26-Jun-2012 [ | E-mail | Share ] Contact: Debbe Geiger Debbe.Geiger@duke.edu 919-660-9461 Duke University Medical Center DURHAM, N.C. The clot-busting medicine, tPA (tissue plasminogen activator), is safe to use in acute stroke patients already on the home blood thinner warfarin, according to researchers from Duke Clinical Research Institute (DCRI). This study helps allay previous concerns that tPA was too dangerous to use in patients on home anticoagulation and would lead to high risk for potentially fatal intracranial bleeding. "To date, we have no randomized trials or large cohort studies to guide us," says Ying Xian, M.D., Ph.D., assistant professor of medicine at Duke, and first author of the study published today in JAMA. "Our large national study found no statistically significant increase in risk, which supports using intravenous tPA in warfarin-treated patients following stoke if their INR is less than or equal to 1.7." The International Normalized Ratio (INR) measures the rate at which blood clots while taking anti-clotting medications like warfarin. The Duke researchers also found almost half of warfarin-treated patients who might have qualified for tPA following stroke did not receive treatment, according to DCRI Director Eric Peterson, M.D., the paper's senior author. "We noted … Continue reading

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Neuroprotective dietary supplements for chronic spinal cord injury

Posted: Published on June 27th, 2012

Public release date: 26-Jun-2012 [ | E-mail | Share ] Contact: Gillian Shasby gshasby@thejns.org 434-924-5555 Journal of Neurosurgery Publishing Group Charlottesville, VA (June 26, 2012). Researchers from the Department of Neurosurgery at the David Geffen School of Medicine and the Department of Integrative Biology and Physiology at UCLA have found that a diet enriched with docosahexaenoic acid (DHA), an omega-3 fatty acid, and curcumin, a component of the Indian spice turmeric, can protect the injured spinal cord and minimize the clinical and biochemical effects of spinal cord myelopathy in rats. This finding is fleshed out in the article "Dietary therapy to promote neuroprotection in chronic spinal cord injury. Laboratory investigation," by Langston Holly, M.D., and colleagues, published today online in the Journal of Neurosurgery: Spine. DHA reduces inflammation and provides structural material to plasma membranes. Curcumin produces strong anti-inflammatory and antioxidant effects. Both agents are safe to use and have been documented to have positive effects on the injured brain. Thus the researchers hypothesized that the combined effects of DHA and curcumin could protect the spinal cord from the cascade of cellular and related biological injuries that result from chronic cord injury. Cervical spondylotic myelopathy is the most common disorder … Continue reading

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Curry spice, omega-3 fatty acid preserve walking ability following spinal-cord injury

Posted: Published on June 27th, 2012

ScienceDaily (June 26, 2012) UCLA researchers discovered that a diet enriched with a popular omega-3 fatty acid and an ingredient in curry spice preserved walking ability in rats with spinal-cord injury. Published June 26 in the Journal of Neurosurgery: Spine, the findings suggest that these dietary supplements help repair nerve cells and maintain neurological function after degenerative damage to the neck. "Normal aging often narrows the spinal canal, putting pressure on the spinal cord and injuring tissue," explained principal investigator Dr. Langston Holly, associate professor of neurosurgery at the David Geffen School of Medicine at UCLA. "While surgery can relieve the pressure and prevent further injury, it can't repair damage to the cells and nerve fibers. We wanted to explore whether dietary supplementation could help the spinal cord heal itself." The UCLA team studied two groups of rats with a condition that simulated cervical myelopathy -- a progressive disorder that often occurs in people with spine-weakening conditions like rheumatoid arthritis and osteoporosis. Cervical myelopathy can lead to disabling neurological symptoms, such as difficulty walking, neck and arm pain, hand numbness and weakness of the limbs. It's the most common cause of spine-related walking problems in people over 55. The first … Continue reading

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Researchers say Parkinson's cure may lie in the nose

Posted: Published on June 27th, 2012

LOUIVILLE University of Louisville researchers hoping to find a cure for Parkinsons disease have discovered an unlikely potential treatment -- stem cells from the human nose. Videos from a laboratory at Louisville reveal the promise: One shows a rat with a brain damaged to mimic Parkinsons continually circling the bottom of a bowl in one direction, unable to do anything else. Another shows a similar rat injected with nasal stem cells moving normally and trying to climb out. The research -- which uses an adult patients own cells -- is outlined in this months issue of the journal Stem Cells Translational Medicine. I think it would be wonderful to have thought of something that could help people. Thats what Im in this for, said Louisville neuroscientist Fred Roisen, chief science officer and co-founder of a company based on the technology called RhinoCyte. Parkinsons -- which afflicts about a million Americans, including Louisville-born boxing legend Muhammad Ali -- is a progressive neurological disorder that mostly strikes people over 50, causing tremors, slow movement and other problems. It occurs when nerve cells in the brain that produce dopamine, a chemical that helps control muscle movement, are slowly destroyed. It is a terrible … Continue reading

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Finding Brings Scientists One Step Closer To Parkinson's Drug

Posted: Published on June 27th, 2012

GRAND RAPIDS, Mich., June 27, 2012 /PRNewswire/ --Van Andel Institute announces that researchers at Lund University in Sweden have published a study detailing how Parkinson's disease spreads through the brain. Experiments in rat models uncover a process previously used to explain mad cow disease, in which misfolded proteins travel from sick to healthy cells. "A major unmet medical need is a therapy that slows disease progression," said Patrik Brundin M.D., Ph.D., Jay Van Andel Endowed Chair in Parkinson's Research at Van Andel Research Institute (VARI), Head of the Neuronal Survival Unit at Lund University and senior author of the study. "We aim to better understand how Parkinson's pathology progresses and thereby uncover novel molecular targets for disease-modifying treatments." Previous research demonstrates that a misfolded protein gradually appears in healthy neurons transplanted to the brains of Parkinson's patients. In the current study, published this week in the Public Library of Science (PLoS) One, researchers were able to follow events in the recipient cell as it accepts the diseased protein. The experiments also show how the transferred proteins attract proteins in the host cell leading to abnormal folding or "clumping" inside the cells. "This is a cellular process likely to lead to … Continue reading

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Cadott mother takes life ‘one day at a time’ with disabled son

Posted: Published on June 27th, 2012

CADOTT Tyler Kenealy will tell you his whole life story, sparing few details, if you ask him about it. And its quite a story to tell. For an 11-year-old boy, hes had his share of struggles, even starting before he was born. Mom was shot, which was not the greatest thing in the world, Tyler said, referencing his mother Liz being injured by gunfire in May 2000. She was one of five people shot during a standoff between her then-fiance, Tom Kenealy, and Chippewa County Deputy Bill Kelly in the town of Edson. Liz Kenealy found out after being taken to the hospital that day that she was about 12 weeks pregnant. I said to the doctor, Are you sure you have the right patient? Liz recalls. The hardships didnt end there. Tyler was born on Aug. 24, 2000, about three months premature, with cerebral palsy. A fighter Cerebral palsy is a group of disorders that can involve brain and nervous system functions, including a persons movement, learning, hearing, seeing, and thinking. It has several variations, and is usually caused by injuries or abnormalities of the brain either in the womb or during the first two years of life. In … Continue reading

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Mom Turns To Kickstarter For Help With Son’s Cerebral Palsy

Posted: Published on June 27th, 2012

Looking for a way to pay for treatment for her son with cerebral palsy, one Oregon mom decided to write a book and turned to Kickstarter.com to fund it. Even she was surprised by the result. Former journalist Shasta Kearns Moore wrote Dark & Light: A love story for babies, after noticing that her 2-year-old twin boys loved simple books with little text and silhouettes rather than intricate illustrations. The Portland-area mom hoped that the board book could help fund costly therapies that are helping one of her twins, Malachi Millard, who has cerebral palsy. Rather than look for a publisher, Kearns Moore started a Kickstarter campaign asking everyday people to pledge money toward publication of the book. She hoped to raise $5,000, but has far surpassed that initial goal. The campaign, which ends Wednesday, already has over $9,600 pledged from 244 individuals. Just having people stand behind us and say, Life dealt you a rough hand, but were going to help you make something awesome out of it, means more than I can ever express, Kearns Moore told the Portland Tribune. To read more click here. See original here: Mom Turns To Kickstarter For Help With Son’s Cerebral Palsy … Continue reading

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Portland mom uses Kickstarter book project to fund son's cerebral palsy treatment

Posted: Published on June 27th, 2012

Kickstarter has become popular as a platform for raising money for creative projects, and now a Portland mom has put it to a double-pronged use: selling a children's board book she wrote to raise money for treating a son with a disability. Shasta Kearns Moore, a former journalist and current Oregonian News Network partner, blogs about her identical twin boys -- Malachi, who has cerebral palsy, and Jaden, who does not, and who turn 2 today -- at OutrageousFortune.net. She recently answered questions by email about her Kickstarter project, a board book called "Dark & Light: A Love Story for Babies," and shared tips for parents of children with disabilities. On 'Dark & Light': "I was laying down to take a nap and thinking about my kids' favorite books -- which were filled with very simple silhouettes. I knew from studies about babies preferring black-and-white pictures that these images were far more interesting and instructive to them than something more complex, like watercolors. But because the books were so simple, and they wanted them read over and over again, I was extremely bored. So in that dreamy space before sleep I started thinking about black and white and how they … Continue reading

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