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Rudimentary Liver Grown in the Lab

Posted: Published on June 20th, 2012

Image: NASA, Johnson Space Center From Nature magazine Japanese scientists have used induced stem cells to create a liver-like tissue in a dish. Although they have yet to publish their results and much work remains to be done, the achievement could have big clinical implications. If the results bear out, they would also constitute a significant advance in the ability to coax stem cells to self-organize into organs. The work was presented by Takanori Takebe, a stem-cell biologist at Yokohama City University in Japan, at the annual meeting of the International Society for Stem Cell Research in Yokohama last week. It blew my mind, said George Daley, director of the stem-cell transplantation programme at the Boston Childrens Hospital in Massachusetts, who chaired the session. It sounds like a genuine advance, says Stuart Forbes, who studies liver regeneration at the University of Edinburgh, UK. Forbes, who also works as a consultant for Scotlands liver-transplantation unit, says that the advance could one day help to avoid the bleak outcome currently experienced by the many patients who dont survive long enough to get a new liver. But the liver described by Takebe has a long way to go before that. Takebe told how … Continue reading →

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Step closer to stem cell answer for human diseases

Posted: Published on June 20th, 2012

Development of stem cell research for treating human cells damaged through injury, disease or ageing has taken a step forward in Queensland. Stem Cells Ltd, based at the Australian Institute for Bioengineering and Nanotechnology at The University of Queensland, is set to receive $470,000 in Queensland Government science funding. The funding will ensure the growth of stem cell research in Queensland, taking the state's leaders closer to developing cell-based therapies for a host of diseases. Stem Cells Ltd Queensland manager Victoria Turner said her team would work with stem cell scientists to advance research into diseases such as schizophrenia, Down syndrome, Parkinson's disease and heart disease. Ms Turner said Stem Cells Ltd would ensure Queensland remained at the forefront of cutting-edge stem cell research. Stem cell research is an exciting and rapidly expanding field that is vital for basic research and understanding of diseases, she said. Most importantly, stem cells are set to have a major impact on healthcare and innovation, offering novel scientific insights that can be used to direct the treatment of a multitude of diseases and, ultimately in the future development of cell-based therapies when cells become damaged by illness or injury. Stem Cells Ltd is a … Continue reading →

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'Master molecule' may improve stem cell treatment of heart attacks

Posted: Published on June 20th, 2012

ScienceDaily (June 20, 2012) Johns Hopkins researchers have discovered that a single protein molecule may hold the key to turning cardiac stem cells into blood vessels or muscle tissue, a finding that may lead to better ways to treat heart attack patients. Human heart tissue does not heal well after a heart attack, instead forming debilitating scars. However, for reasons not completely understood, stem cells can assist in this repair process by turning into the cells that make up healthy heart tissue, including heart muscle and blood vessels. Recently, doctors elsewhere have reported promising early results in the use of cardiac stem cells to curb the formation of unhealthy scar tissue after a heart attack. But the discovery of a "master molecule" that guides the destiny of these stem cells could result in even more effective treatments for heart patients, the Johns Hopkins researchers say. In a study published in the June 5 online edition of journal Science Signaling, the team reported that tinkering with a protein molecule called p190RhoGAP shaped the development of cardiac stem cells, prodding them to become the building blocks for either blood vessels or heart muscle. The team members said that by altering levels of … Continue reading →

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Saint Luke’s Neuroscience Institute’s Stroke Program Found to Substantially Improve Access to Care and Drive Better …

Posted: Published on June 20th, 2012

WAUKESHA, Wis.--(BUSINESS WIRE)-- GE Healthcare, a unit of General Electric Company (GE), announced today, in collaboration with Saint Lukes Neuroscience Institute (SLNI) in Kansas City, Mo., the first healthymagination care area validation for stroke. This distinction means that SNLIs stroke program contributes to GEs goal to improve access to and quality of healthcare by 15 percent. Evidence verified by external independent experts at Oxford Analytica shows that SNLIs program for coordinated use of people, process and technologyits stroke solutionyields better patient outcomes. Through this validation, Saint Lukes is designated this first healthymagination stroke solution site in the world. The SNLI Stroke Solution joins GEs more than 60 innovations currently healthymagination validated. To establish Saint Lukes as a healthymagination solution site, GE Healthcare applied the same rigorous process it uses to validate its own innovations potential to improve quality of, increase access to or lower the cost of care. For this validation, the team evaluated treatment, access and outcomes among Saint Lukes stroke patients compared to national benchmarks for other stroke centers and hospitals. Treatment The SLNI Stroke Solution uses tissue plasminogen activator (tPA) therapy as a treatment. Tissue plasminogen activator (tPA) is currently the only U.S. Food and Drug Administration … Continue reading →

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Raptor Pharmaceutical Licenses Intellectual Property Related to Parkinson's Disease From Universite Laval

Posted: Published on June 20th, 2012

NOVATO, Calif., June 20, 2012 (GLOBE NEWSWIRE) -- Raptor Pharmaceutical Corp. ("Raptor" or the "Company") (RPTP), today announced that the Company has acquired exclusive rights to intellectual property related to cysteamine and related compounds in the potential treatment of Parkinson's Disease from Universite Laval ("Laval"), Quebec, Canada. Raptor's agreement with Laval provides exclusive rights to technology related to the use of cysteamine and related compounds to potentially modify the progression of Parkinson's Disease. Researchers at Laval reported that administration of cystamine (an oxidized form of cysteamine) in an animal model of Parkinson's Disease showed signs of preventing neuron loss and rescuing neurons undergoing a degenerative process. Signs of restoration and partial reversal of behavioral impairments were also observed. Dr. Patrice P. Rioux, Raptor's Chief Medical Officer, stated, "The agreement with Laval extends our existing portfolio in neurodegenerative diseases. We are currently conducting a Phase 2/3 clinical trial in France of Delayed-release Cysteamine Bitartrate capsules (RP103), for the potential treatment of Huntington's Disease. The researchers at Laval have compiled a solid preclinical foundation which, when combined with the existing safety profile of cysteamine, may enable us to more rapidly advance this program for the potential treatment of Parkinson's Disease in to … Continue reading →

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New Parkinson's care guidelines unveiled

Posted: Published on June 20th, 2012

Date: Wednesday Jun. 20, 2012 8:28 AM ET TORONTO Canada now has a set of national guidelines aimed at establishing a consistent standard for diagnosis and treatment of Parkinson's disease across the country. The guidelines, developed by neurologists and movement disorder specialists, are designed to provide information and advice to family physicians and other health-care professionals, with the goal of improving care for people with the progressive neurological disease. "Most Canadians with Parkinson's do not attend specialized Parkinson's or movement disorders clinics," said guidelines editor Dr. David Grimes, director of the Parkinson's disease and movement disorders clinic at the Ottawa Hospital. "A tool was needed so that all health-care providers who treat people with Parkinson's in Canada have a clear idea on how best to help individuals manage their disease. "The guidelines are meant to improve the standard of care and access to care for people with Parkinson's in all regions of Canada." Joyce Gordon, president and CEO of Parkinson Society Canada, said she believes the guidelines will result in earlier diagnosis, better treatment and management of symptoms, and an improved quality of life for people with the disease. An estimated 100,000 Canadians have Parkinson's, which occurs most commonly in … Continue reading →

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Research and Markets: Parkinson's Disease Therapeutics – Global Drug Forecasts and Treatment Analysis to 2020

Posted: Published on June 20th, 2012

DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/b29h7z/parkinsons_diseas) has announced the addition of GlobalData's new report "Parkinson's Disease Therapeutics - Global Drug Forecasts and Treatment Analysis to 2020" to their offering. Parkinson's Disease Therapeutics - Global Drug Forecasts and Treatment Analysis to 2020 GlobalData has released its pharma report, Parkinson's Disease Therapeutics - Global Drug Forecasts and Treatment Analysis to 2020. The report is an essential source of information and analysis on the global Parkinson's disease Therapeutics therapeutics market. The report provides comprehensive information on Parkinson's Disease Therapeutics, highlighting the treatment guidelines. It identifies and analyses the key trends shaping and driving the global Parkinson's Disease Therapeutics therapeutics market. It analyses the treatment usage patterns in the global Parkinson's Disease Therapeutics therapeutics market. The report also provides insights into the competitive landscape and the emerging players expected to significantly alter the positions of the existing market leaders. The report provides valuable insights into the pipeline products within the global Parkinson's Disease Therapeutics sector. It quantifies the unmet need in the global Parkinson's Disease Therapeutics therapeutics market as well as in the individual markets such as the US and the top five countries in Europe, highlighting the opportunity for future players. This report is … Continue reading →

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News Articles

Posted: Published on June 20th, 2012

Kristi's Kids - Sienna needs your help ${title} Views: ${media:community.statistics.views} Rating: ${media:community.starRating.average} ${created} News Articles Posted 8:20 PM 6/19/2012 : Kristi's Kids - Sienna needs your help Tucson - A tiny Tucsonan, diagnosed with cerebral palsy and microcephaly needs your help. Sienna Pineiro isn't even two years old yet and her skull is hardly growing. For head size, she falls in the 2-5 percentile. She should be higher than 10%. Sienna's mom, Ceres Pineiro, has done extensive research and she says, most of the treatments aren't covered by insurance. Ceres says, "...they're more like let's manage it. Let's get her braces and do those kinds of things'... Some kids with Microcephaly fare well. Sometimes they have a decreased life span and they're slow mentally." The longer Sienna goes, without treatment, the more her head size will fall behind, causing brain damage. Susan Rodriguez, with Rapid Recovery Hyperbarics (in California,) evaluated Sienna and thinks she could benefit from shallow depth hyperbaric treatments. She says, "you're gonna stimulate the skull to grow a little bit more and catch up with her. I don't think she's that far behind. She doesn't appear to be." While Ceres continues good nutrition and physical therapy for … Continue reading →

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Police roundup | Brain injury victim’s boyfriend charged

Posted: Published on June 20th, 2012

Police Brain injury victims boyfriend charged A 46-year-old woman was treated for bleeding from her brain at a Charleston area hospital and a Myrtle Beach man was charged with beating her, according to a police report. Thomas Edward Cooper, 38, is charged with criminal domestic violence of a high and aggravated nature and is being held at the Myrtle Beach Jail pending a bond hearing, according to jail records. Cooper was arrested at 4 p.m. Monday in the 200 block of 26th Avenue South, according to an arrest report. The charge stemmed from officers being called at 5:30 a.m. Sunday to Waccamaw Community Hospital where the victim sought treatment, police said. The victim told officers that about 7:30 p.m. Saturday she went to Coopers apartment and he accused her of cheating on him. The victim said Cooper, her boyfriend, pushed her, punched her in the face, repeatedly choked her on the bed and held her in the apartment, according to the report. The victim said a 62-year-old woman, who also was inside the apartment, provoked Cooper during the incident and pushed the victim down multiple times to keep her from leaving the apartment, according to the report. After about 30 … Continue reading →

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Traumatic brain injury the focus of American Headache Society scientific conference

Posted: Published on June 20th, 2012

Public release date: 20-Jun-2012 [ | E-mail | Share ] Contact: Dennis Tartaglia dtartaglia@tartagliacommunications.com 732-545-1848 Tartaglia Communications The impact of traumatic injuries to the brain whether sustained in combat or on the playing fields of America's schools is a major topic for international migraine specialists the week of June 18 as they gather in Los Angeles for the 54th Annual Scientific Sessions of the American Headache Society. This is among many timely issues concerning headache, migraine, and brain injuries on the four-day agenda here which runs through Sunday morning, June 24. "As migraine specialists, we cannot ignore the fact that traumatic brain injury (TBI) is an increasingly common medical problem today and that those who experience severe and untreated blows to the brain may end up with serious neurological damage and long-lasting medical and psychological problems," said Elizabeth Loder, MD, MPH, president of the American Headache Society (AHS) and Chief of the Division of Headache and Pain in the Department of Neurology at the Brigham and Women's Hospital in Boston. "We owe it to our nation's military as well as to our children in contact sports to raise awareness of TBI and make this issue a national health priority." Dr. … Continue reading →

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