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Progesterone may save traumatic brain injury patients

Posted: Published on June 20th, 2012

Contributor (888) 633-0360 A young woman has been given a second chance at life after a pedestrian accident that couldve left her an invalid with traumatic brain injury. Eighteen-year-old Michelle Vaquero wound up on the wrong side of a car while crossing the street. The was sent soaring 30 feet away from the initial contact. Doctors didnt give Michelles mom, Miriam, much optimism. The impact was so severe that they didnt give us any hope, she told the New York Times. They didnt tell us shed be fine. They didnt know how bad it was. Michelles mother had reason to worry since traumatic brain injury has been known to cause permanent disability and even death. According to the Centers for Disease Control and Prevention, each year, nearly 1.7 million Americans suffer some type of traumatic brain injury, which can range from mild to severe. In most cases people suffer from a mild traumatic brain injury, which are usually various forms of concussions. About 275,000 people are hospitalized annually, and about 50,000 die from the severity of the injury. Thanks to a medical study, Michelle may beat those odds. The Times reports that upon her arrival at the hospital, she was … Continue reading

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When Science Meets The Cure | The Cure For Diseases – Video

Posted: Published on June 20th, 2012

19-06-2012 03:10 ISN'T THAT AN AMAZING BREAKTHROUGH? A ONE CURE FOR ALL DISEASES INCLUDING CANCER! To go with your life and lifestyle smoothly and no risks in being sick! Would it not be a reason for you to find out about HOW you can have these? To make you live your life and your family's life in good health and to not worry suffering ailments ever? What we have for you is an innovation of scientific study that will be very helpful to all and beneficial to people. You can watch your children grow and reach their stars. A revolutionary breakthrough made by Canadian Doctor that was meant to cure almost any kind of diseases effectively. Diseases as cancer, Alzheimer, diabetes, AIDS, Parkinson disease, hepatitis, heart disease, multiple sclerosis, alcoholism, emphysema, rheumatoid arthritis, periodontal disease, asthma and many others. This was scientifically proven on 1929, where the Doctor injected an extract from the hen egg to his patients. The Canadian Doctor by injecting the avian extract and other important nutrients, it simultaneously revitalized and rejuvenated to healthy cells. Healthy and rejuvenated cells can fight against diseases. THE ORIGIN OF CANCERThis is the most valuable article that will greatly help your … Continue reading

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What is Multiple Sclerosis – Video

Posted: Published on June 20th, 2012

19-06-2012 10:44 Visit my youtube channel at What is Multiple Sclerosis? Multiple sclerosis (MS), also known as "disseminated sclerosis" or "encephalomyelitis disseminata", is an inflammatory disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading to demyelination and scarring as well as a broad spectrum of signs and symptoms. Follow this link: What is Multiple Sclerosis - Video … Continue reading

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The Multiple Sclerosis Therapy Market is on the Verge of an Overhaul – Video

Posted: Published on June 20th, 2012

19-06-2012 11:39 It's tragic to be sure, even if it takes a celebrity to bring the problem to light. Jack Osbourne - son of pop singer Ozzy Osbourne - was diagnosed with multiple sclerosis several days ago. As is likely the case with any newly-diagnosed MS sufferer, the question he soon began as king is, "Now what?" The answer was, though brave, also obvious... begin treatments, and fight. Unfortunately, Osbourne soon found out what the United States' 400000 multiple sclerosis patients (and the world's 2.5 million MS patients) already know too well... there is no cure, and treatment options aren't all that great either. That may not be the case for much longer, however. Though a true 'cure' isn't on the table yet, some treatments are proving to be effective, and a cure isn't out of the question.One of the more effective treatments us a drug called Fampyra, jointly made by Biogen Idec (NASDAQ:BIIB) and Acorda Therapeutics Inc. (NASDAQ:ACOR). Though the drug was approved for specific use - to improve casual walking in multiple sclerosis patients - in the United States a couple of years ago, it was only approved for the same use in Europe late last month. It's … Continue reading

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Detector of DNA damage: Structure of a repair factor revealed

Posted: Published on June 20th, 2012

ScienceDaily (June 19, 2012) Double-stranded breaks in cellular DNA can trigger tumorigenesis. LMU researchers have now determined the structure of a protein involved in the repair and signaling of DNA double-strand breaks. The work throws new light on the origins of neurodegenerative diseases and certain tumor types. Agents such as radiation or environmental toxins can cause double-stranded breaks in genomic DNA, which facilitate the development of tumors or the neurodegenerative disorders ataxia telangiectasia (AT) and AT-like disease (ATLD). Hence efficient repair mechanisms are essential for cell survival and function. The so-called MRN complex is an important component of one such system, and its structure has just been elucidated by a team led by Professor Karl-Peter Hopfner of LMU's Gene Center. Malignant mutations The MRN complex consists of the nuclease Mre11, the ATPase Rad50 and the protein Nbs1. Nbs1 is responsible for recruiting the protein ATM, which plays a central role in early stages of the cellular response to DNA damage, to the site of damage. "How the MRN complex actually recognizes double-stranded breaks is still not clear," says Hopfner. He and his colleagues therefore set out to clarify the issue by analyzing the structures of mutant, functionally defective versions of … Continue reading

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Testosterone Therapy: A Misguided Approach to Erectile Dysfunction (ED)

Posted: Published on June 20th, 2012

NEW YORK, June 19, 2012 /PRNewswire/ -- Historically, low testosterone in men was commonly blamed for the inability to achieve and sustain an erection and hormone replacement therapy was considered the fix. Today, however, significant progress has been made in diagnosing the causes of erectile dysfunction (ED) and targeting the right treatment method for individual men. (Photo: http://photos.prnewswire.com/prnh/20120619/NY26458) The hormone testosterone is responsible for the development and maintenance of male reproductive tissues and typical male characteristics. "Testosterone and manliness are linked in our minds," Dr. J. Francois Eid says, "and so many men with ED issues quickly blame their testosterone level." Eid is a world renowned urologist who specializes inED treatment, penile implantsandpenile prosthesis surgery with his innovative "No Touch Surgical Technique." He is Clinical Associate Professor of Urology at the Weill -Cornell Medical College of Cornell University and Director of Advanced Urological Care, PC in Manhattan, NY. Problematically, many doctors make the same mistake and set men with erectile dysfunction on a course of androgen replacement therapy that can actually do a disservice to the patient. Aggressive marketing and pressure from the pharmaceutical industry further exacerbate the dangerous practice of hormone replacement therapy. Some of the long-term effects of … Continue reading

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European researchers crack embryonic stem cells mystery

Posted: Published on June 20th, 2012

European researchers discover that embryonic stem cell properties are impacted by the laboratory conditions used to grow them. In their groundbreaking study, a European team of researchers evaluated embryonic stem cells grown in a pure undifferentiated state. The use of next generation sequencing technology enabled them to analyse gene expression (i.e. transcriptome) and chromatin modifications (i.e. epigenome). The study is presented in the journal Cell. The results pinpoint key differences between pure stem cells and embryonic stem cells grown in laboratory settings. What allows embryonic stem cells to stay pluripotent? Researchers have been investigating this mystery for some time. Now a team of researchers from Germany, the Netherlands and the United Kingdom provide key answers, giving us information we need to know about how cells are controlled and what is the optimal way to grow them. The findings overturn previous reports suggesting that embryonic stem cells are both unstable and primed to differentiate. This information could help lead to the development of new and effective treatments. Researchers from Nijmegen Centre for Molecular Life Sciences (NCMLS) and Radboud University in the Netherlands, as well as the Wellcome Trust Centre for Stem Cell Research, Stem Cell Institute and the University of Cambridge … Continue reading

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The Hospital for Sick Children in Toronto Adopts Life Technologies' Ion Proton™ Sequencer to Launch New Centre for …

Posted: Published on June 20th, 2012

CARLSBAD, Calif., June 19, 2012 /PRNewswire/ -- Life Technologies Corporation (LIFE) today announced it has partnered with The Hospital for Sick Children (SickKids) to advance pediatric genomic research on the Ion Proton Sequencer. Under the agreement, the semiconductor-based platform will be the primary instrument on which multiple clinical research samples will be mapped daily on four sequencers in the hospital's newly launched Centre for Genetic Medicine. SickKids and Life Technologies will collaborate on developing sequencing workflows and protocols for the Ion Proton System that are tailored for studies of interest to researchers in the Centre. The first collaborative project will focus on sequencing clinical research samples to better understand the genetics behind autism, with a long-term goal to sequence up to 10,000 genomes per year to study various diseases in children. "The perfect storm of unparalleled advances in genome sequencing technology and information science, and a captivated hospital striving for new ways to move forward in medical treatment, bring us to this important day," says the new Centre's Co-Director, Dr. Stephen Scherer, who also leads The Centre for Applied Genomics at SickKids and the University of Toronto's McLaughlin Centre. "We are very excited to work with Life Technologies to enhance … Continue reading

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Genetic testing to choose the right antidepressant

Posted: Published on June 20th, 2012

Psychiatrists often try two or more medications in a patient suffering with major depression before settling on the one that seems to work best for that individual. Sometimes, after several are tried and abandoned, two (or even three) are used in combination. Medication selection is part of the art of psychiatry, but, now, testing is available that promises to make it more of a science. A company called AssureRx Health now offers what it calls GeneSightRxpharmacogenomic laboratory testing that helps identify which antidepressants are a good match for a persons genetic makeup, and which are not so good a match. Sometimes, the testing reveals why three or four antidepressants havent worked for a patient, while pointing in the direction of one that might. This is extremely good news, because psychiatrists have several different kinds of antidepressants to choose fromsome which increase the activity of the brain chemical messenger serotonin, some which increase the activity of the brain chemical messenger norepinephrine and some which increase both. And they do so by varying mechanisms, requiring the activity of different enzymes. The technology behind GeneSightRx actually determines which genetic variantsin terms of the enzymes that are activated by antidepressantsa person possesses. Different antidepressants … Continue reading

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Metformin treatment caused cancer stem cell death in pancreatic cancer cell lines

Posted: Published on June 20th, 2012

Public release date: 19-Jun-2012 [ | E-mail | Share ] Contact: Jeremy Moore jeremy.moore@aacr.org 215-446-7109 American Association for Cancer Research LAKE TAHOE, Nev. Results of some preclinical trials have shown that low doses of the antidiabetic drug metformin may effectively destroy cancer stem cells, a group of cells that are considered to be responsible for tumor initiation and, because they are resistant to standard chemotherapies, tumor relapse. In addition, when metformin was combined with a standard chemotherapy used for pancreatic cancer, the combination treatment was able to efficiently eradicate both cancer stem cells and more differentiated cancer cells, which form the bulk of the tumor, according to data presented by Christopher Heeschen, M.D., Ph.D., at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, held in Lake Tahoe, Nev., from June 18-21, 2012. Heeschen is professor for experimental medicine at the Spanish National Cancer Research Centre in Madrid, Spain. Most clinical trials of pancreatic cancer conducted during the last 15 years have failed to show marked improvement in median survival, suggesting that the selected approaches were not sufficient for several reasons, according to Heeschen. In recent years, researchers have identified cancer stem cells which, as opposed to … Continue reading

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