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Prenatal genetic test offers more information, raises questions

Posted: Published on June 16th, 2012

CHICAGO - The latest advance in prenatal genetic testing purports to offer parents more detailed information than ever about the child they are expecting. But for some, the new answers could lead to another round of questions. The technology allows doctors to detect small or subtle chromosomal changes in a fetus - such as missing or extra pieces of DNA - that could be missed by standard tests. Most parents will get results confirming a normal pregnancy. But some will learn that their baby has a birth defect, a developmental problem or other medical condition, and in a small number of cases the test will detect things that no one knows quite how to interpret. The information can allow parents to prepare for early intervention and treatment, but it also could raise questions about terminating the pregnancy or lead to nagging worry over uncertain results. The Reproductive Genetics Institute in Chicago, which has helped pioneer the rapidly developing field of prenatal diagnosis and testing, recently began offering the procedure - array comparative genomic hybridization, or array CGH for short - to any pregnant woman who wants it. "The technology has been available for a number of years . but it … Continue reading →

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Fundraising gala takes aim at pancreatic cancer

Posted: Published on June 16th, 2012

FIGHTING BACK: Pancreatic cancer claimed our town's Milton Wong recently, Jack Poole last year and Betty Ergas before that. Ergas's daughter, Myriam Glotman, and husband Geoffrey later raised some $300,000 to support research. This week, they had Dr. Daniel Renouf explain to reception guests how the BC Cancer Agency's Pancreatic Cancer Research Initiative will team genome analysis, clinical trials and nanomedicine technology against the lethal ailment. Myriam and Jane Hungerford will chair the fundraising Inspiration Gala Nov. 1, with Wong's widow Fei as honorary chair. HOMELESS PRAYER: Give us this night our nightly bed. NO SMILE, WE'RE MOD-ELS: Fashion designer Jason Matlo was ear-to-ear cheery when stony-faced catwalkers showed his fall-winter ready-to-wear line at the Shangri-La Hotel Thursday. It was a teaser for the global Fashion's Night Out celebration that should have retailers, restaurateurs, bartenders and even models grinning here Sept. 6. HAWAII NINE-O: Wendy McDonald celebrated her 90th unquietly this week with a luau for hundreds of florally attired friends and family at North Vancouver's Pinnacle hotel. Thrice-widowed, McDonald sparked decades of respectful ribaldry by owning and running a ball-bearing firm with the kind of iron resolve that year-round sea bathing never rusted. Matching her manner, 94-year-old bandleader Dal … Continue reading →

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Asia needs to fix financial safety net

Posted: Published on June 16th, 2012

Ministers and governors posing for a picture after the 15th Asean + 3 Finance Ministers and Central Bank Governors meeting in Manila May 3, 2012last month. China, Japan and South Korea agreed on Thursday to boost cross-investment in government bond markets, worth nearly a combined US$15 trillion, in a move that will better prepare the countries to protect their financial markets from external shocks. Reuters pic announced a package of initiatives designed to ensure their economies do not succumb to another balance of payments crisis. Reuters pic ASIA'S recent doubling of its financial safety net looks impressive. But it's more icing than cake. It is, in fact, unusable. There is no fund but a series of promises, the institutional mechanisms to replace International Monetary Fund (IMF)-type surveillance and conditionality have not been established, and there are no rapid-response procedures to handle a fast-developing financial emergency. With much fanfare, 3 East Asian (China, South Korea and Japan) and 10 Southeast Asian finance ministers, or Asean+3, last month announced a package of initiatives designed to ensure their economies do not succumb to another balance of payments crisis. They relate to the Chiang Mai Initiative Multilateralisation (CMIM), a self-managed reserve-pooling mechanism for its … Continue reading →

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Business briefs

Posted: Published on June 16th, 2012

SEC exit Eileen Rominger, the former Goldman Sachs exec who joined the SEC last year, will step down next month as head of the agencys investment management unit. Drug scam US authorities arrested Andrew Strempler, 38, a pioneer of the Canadian Internet pharmacy industry, on charges related to the sale of foreign and counterfeit medicines. Stremplers former company, RxNorth.com, sold and shipped fake and otherwise misbranded drugs, the feds said. Juicy Apple I An Apple I Computer from 1976 sold at Sothebys auction house for $374,500, or more than 500 times its original retail price. Amazon tune Amazon.com has agreements with the four major US record companies for the rights to start a music service that lets users store songs on a remote server and access them online, people familiar with the matter said. Seacrest bid American Idol host Ryan Seacrest is contemplating a bid for Dick Clark Productions, the Wall Street Journal reported, citing sources. The company produces various awards shows, including the Golden Globes and the annual New Years Eve special that the late Clark hosted for decades. Seacrest now hosts that show. The rest is here: Business briefs … Continue reading →

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From an inventor of Viagra, a spray to help love last beyond a moment

Posted: Published on June 16th, 2012

By Fiona Macrae and Roger Dobson PUBLISHED: 18:36 EST, 15 June 2012 | UPDATED: 18:55 EST, 15 June 2012 Pocket-sized solutions: The Tempe spray helps prevents premature ejaculation He put smiles on millions of faces when he helped invent Viagra. Now the brains behind the little blue pills claims to have done it again. Mike Wyllie, one of the team of scientists who developed Viagra in the 1990s, has created a drug that tackles premature ejaculation. He predicts the spray-on medication, designed to prolong the joy of sex for millions of sufferers and their partners, is likely to become the next blockbuster drug. Premature ejaculation affects more than one in four men making it more common than the impotence tackled by Viagra. Most are too embarrassed to seek help and when they do, treatments are generally limited to powerful anti-depressants and counselling. There is one pill specifically designed to treat the problem but it is expensive and not widely available in the UK. In contrast, it is hoped the spray, called Tempe, which could be on sale within months, will be cheap enough for prescription on the NHS. In trials, some men using the spray ahead of sex lasted up … Continue reading →

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Corneal Dysfunction – Cell Regeneration May Restore Vision

Posted: Published on June 16th, 2012

Editor's Choice Main Category: Eye Health / Blindness Article Date: 15 Jun 2012 - 15:00 PDT Current ratings for: 'Corneal Dysfunction - Cell Regeneration May Restore Vision' 4 (1 votes) Leading researcher, Noriko Koizumi, MD, PhD, from the Doshisha University's Department of Biomedical Engineering, Faculty of Life and Medical Sciences in Kyotanabe, Japan explained: Previous studies demonstrated that Rho-associated kinase (ROCK) signaling interferes with adhesion.We found that transplanting cultivated CECs in combination with a low-molecular weight compound that inhibits ROCK (ROCK inhibitor Y-27632), successfully achieved the recovery of corneal transparency." The researchers cultivated rabbit CECs in the lab, which they subsequently injected into the anterior chamber of these eyes of rabbits with damaged corneal endothelia.Judging by the recovery of the corneal endothelial function, they discovered that the rabbits' corneas regained complete transparency 48 hours after they were injected with the cultivated cells and Y-27632, whilst the rabbits injected with CECs but without Y-27632 had hazy and severely swollen corneas. The team reported no procedure-related complications, noting that the rabbits in the CEC plus Y-27632 group's reconstructed corneal endothelium regained a normal hexagonal cell shape. The scientists decided to continue their experiments with monkey CECs, as these are more similar to … Continue reading →

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Bio-Matrix Scientific Group Announces David Audley, the Founder of International Cellular Medicine Society, Has Joined …

Posted: Published on June 16th, 2012

SAN DIEGO, CA--(Marketwire -06/15/12)- Bio-Matrix Scientific Group (BMSN) (BMSN) announced today the appointment of David Audley to the advisory board of Its Regen BioPharma subsidiary. Mr. Audley will advise Regen BioPharma on strategic leveraging of national and international clinical research resources. Mr. Audley is viewed by the Company as a key component in the commercialization of stem cell intellectual property. Additionally, it is anticipated that he will assist in raising international awareness for the regenerative therapies being developed by the Company. In his function as executive director and CEO of the International Cellular Medicine Society (ICMS), Mr. Audley has spearheaded development and implementation of global guidelines for accreditation of stem cell clinics. Under his leadership, the ICMS has grown from a loose association of a handful of physicians to a major international standards organization with over 3500 members from 36 countries. He is a strong advocate for stem cell therapy development and implementation, and is the chief architect of the ICMS accreditation program that is currently evaluating the practices of nearly 20 facilities in a dozen countries. Mr. Audley also has strong professional relationships with Ministries of Health and governmental agencies in South America, Asia and the Middle East. "My … Continue reading →

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Carilion will use federal grant to help with prescriptions – www.roanoke.com

Posted: Published on June 16th, 2012

With a $4.2 million, three-year federal grant, Carilion New River Valley Medical Center plans to train pharmacists to play a bigger role in managing patients' prescription drugs and preventing hospital readmissions. The Carilion Clinic hospital was among 81 recipients of Health Care Innovation Awards announced by the U.S. Department of Health and Human Services on Friday. "We think it will really help deliver a completely different level of care and modern care in rural Virginia," said Dr. John Piatkowski, the hospital's administrator. Carilion has teamed up with Virginia Commonwealth University School of Pharmacy, Aetna and CVS Caremark for the grant. The partners will work to provide a new model of managing prescription drugs in patients with chronic disease. In doing this, they estimate that $4.3 million in health care costs can be avoided, with much of the savings from preventing unnecessary hospital readmissions, Piatkowski said. The project will train pharmacists to be more directly involved in patient care, said Bill Lee, the program's lead pharmacist. While pharmacists are involved with patient care during a person's hospital stay, they have little direct interaction with patients and are rarely involved after a patient is discharged. Under the proposed model in the grant, … Continue reading →

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Magnets that mark cancer

Posted: Published on June 16th, 2012

USING magnets to target cancer drug treatment can help reduce serious side effects, Australian scientists have discovered. The side-effects of chemotherapy occur because the drugs attack healthy cells as well as cancers. But a team from the University of Sydney, working with researchers in Scotland, have discovered a way to insert a tiny iron oxide core inside an anti-cancer drug. They then used magnets to guide the drug to the area where it was needed. The discovery has been published in the international scientific journal, Inorganica Chimica Acta. Advertisement: Story continues below Dr Nial Wheate, from the University of Sydney's faculty of pharmacy, said it could mean fewer side effects for cancer patients. ''Many of the side-effects associated with chemotherapy occur because the drugs spread throughout the body, killing healthy organs as well as cancers," he said. "This technology could greatly reduce or even eliminate the severe side effects that people associate with chemotherapy such as hair loss, nausea, vomiting, low red blood cells and an increased risk of infection." When the team placed a magnet under a plate containing cancer cells, the drug destroyed only those cells growing near the magnet, leaving the others unharmed. ''We can potentially direct … Continue reading →

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Chase ends with arrest of pharmacy hold-up suspect

Posted: Published on June 16th, 2012

9:05 AM By BEN MCCANNA Morning Sentinel FAIRFIELD -- A suspect wanted in connection with three pharmacy robberies was caught Friday after an intensive manhunt and a high-speed motorcycle chase ended in a crash. click image to enlarge Shawn Michael Merrill click image to enlarge Police officers stand in the parking lot next to the Kennebec Valley Council of Governments building in Fairfield after the Rite Aid on Main Street was robbed Friday. Staff photo by Ben McCanna Shawn Michael Merrill, 26, a transient, was arrested in Chelsea by Maine State Police about 3:20 p.m., just three hours after he allegedly robbed Rite Aid on Main Street. Merrill is also suspected of two back-to-back robberies on Tuesday -- the Walmart pharmacy in Waterville and Goggins IGA in Randolph. The manhunt began at 1 p.m. Friday, shortly after Merrill allegedly approached a pharmacy clerk with a note demanding drugs. He also lifted his shirt and displayed a handgun tucked into his waistband, Fairfield Police Chief John Emery said. Read more: Chase ends with arrest of pharmacy hold-up suspect … Continue reading →

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