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Unveilling stem cells

Posted: Published on June 15th, 2012

Unveilling stem cells LAWRENCE SERETSE Correspondent Cryo-Save, the European company that intends to establish the first stem cell bank in Botswana says stem cells do not have just one function. They can themselves become or create other types of cells such as blood cells, brain cells, tissue cells, muscle cells and the like. Stem cells can be found in every person but they are much more numerous in the body of a foetus. There are three types of stem cell banking namely, the baby stem cell banking which is the preservation and storage of cord blood and umbilical cord tissue. Adult stem cell banking is the preservation and storage of peripheral blood (from blood stream for bone marrow transplants) and fatty tissue stem cells. The reproductive cell banking deals with the preservation and storage of eggs and sperm for future fertility treatments or artificial insemination purposes. Studying stem cells helped humans understand how they transform into the dazzling array of specialised cells that make us what we are. Some of the most serious medical conditions, such as cancer and birth defects, are caused by problems that occur somewhere in this process. A better understanding of normal cell development has allowed … Continue reading →

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3 Biotech Stocks That Could Change the World

Posted: Published on June 15th, 2012

By Mike Volkin - June 15, 2012 | Tickers: AOL, MSFT, RAI, CIGX, TEVA | 0 Comments Mike is a member of The Motley Fool Blog Network -- entries represent the personal opinions of our bloggers and are not formally edited. 3 Biotech Stocks That Could Change The World By George S. Mack, The Life Sciences Report For more interviews with sector experts and analysts, please sign up for our newsletter at http://www.thelifesciencesreport.com. Every investor is in search of a breakthrough that will change the world. Patrick Cox has seen it all before as an insider at Netscape Communications before it was acquired by AOL Inc. (NYSE: AOL) at the end of 1998 and before Microsoft Corp. (NASDAQ: MSFT) ever noticed that that the world was shifting under its feet. The browser revolution began with the straightforward idea that all computer operating systems could be networked with seamless cross-platform ease. I recently interviewed Cox, now editor of Breakthrough Technology Alert and Technology Profits Confidential, for the story Biotech Ideas That Will Change the World in The Life Sciences Report. He sees a new revolution in progress as stem cell technologies and targeted therapies begin to change the entire paradigm of … Continue reading →

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Cellerant to Present at the International Society for Stem Cell Research (ISSCR) 10th Annual Meeting in Japan

Posted: Published on June 15th, 2012

SAN CARLOS, Calif.--(BUSINESS WIRE)-- Cellerant Therapeutics Inc., a biotechnology company developing novel hematopoietic stem cell-based cellular and antibody therapies for blood disorders and cancer, announced today that Cellerants President and CEO, Ram Mandalam, Ph.D., will be presenting at the International Society for Stem Cell Research (ISSCR) 10th Annual Meeting held June 13 16 in Yokohama, Japan. Dr. Mandalam will be co-chairing a session Stem Cells and Cancer and will be giving a presentation, titled Antibodies Targeting Cancer Stem Cells in Hematological Malignancies, on Saturday, June 16 at 1:30 p.m. JST (Japan time). Dr. Mandalam will provide an overview of Cellerants cancer stem cell discovery approach and new data on its therapeutic antibodies demonstrating activity against acute myelogenous leukemia (AML) cancer stem cells. Cellerant scientist, Anna Sedello, Ph.D. will also be presenting Poster #1144 titled Ex vivo-Generated Mouse Myeloid Progenitor Cells Mitigate Gastrointestinal Acute Radiation Syndrome when Administered up to 5 Days after Irradiation. These results demonstrate that cryopreserved, allogeneic myeloid progenitor cells from mice prevent death from lethal radiation doses known to cause death through hematopoietic and gastrointestinal injury. These results also show that myeloid progenitor cells are one of the most promising radiation countermeasures among all therapeutics currently under … Continue reading →

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Stem cell treatment helps heal stroke victims

Posted: Published on June 15th, 2012

"So it's interesting to see that in all the patients so far they have improved slightly over the course of their involvement in the study." The six patients suffered strokes between six months and five years before they were treated, and all had been left with limb weakness. The patients were assessed using the National Institutes of Health Stroke Scale which ranked the first five patients with a median score of eight before the treatment and four points three months afterwards. The sixth patient was treated less than three months ago. Six further patients will be treated as part of this Phase 1 trial. Professor Muir said he was "intrigued" by the early results. He added: "We know that if you're involved in a trial you are going to see patients change in behaviour, particularly if you're doing something invasive, so we need to be very cautious indeed in interpreting these results. "However, that said, it is not something we'd anticipated seeing in this group of patients." Further trials are needed to establish whether stem cells actually help the brain repair damaged tissue. Michael Hunt, chief executive officer of the company developing the treatment, ReNeuron, said: "The clinical trial is … Continue reading →

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Researchers urge EU not to cut stem cell funding

Posted: Published on June 15th, 2012

* European Parliament debating funding for 2014 to 2020 * Scientists fear cuts to embryonic stem cell research * Experts say cutting funds would hold back entire field LONDON, June 15 (Reuters) - Leading scientists, biomedical research bodies and patient groups urged the European Parliament on Friday to maintain vital European Union funding for studies using embryonic stem cells. Hailing the field as "one of the most exciting and promising" in modern biomedical research, the group said they feared research grants currently under review may be under threat from pro-life European parliamentarians who say public funds should not be spent on embryonic stem cell work. "(EU) Commission funding must be available to continue to support scientists investigating all types of stem cells - including human embryonic stem cells - with potential to make advances in regenerative medicine," they wrote in an open letter released by the Wellcome Trust, a charitable health foundation. The European Parliament is currently debating the future outline of Horizon (Euronext: HOR.NX - news) 2020, the EU's programme for research and innovation which will run from 2014 to 2020. Draft rules provide for stem cell research funding, including embryonic stem cells but some member states have been … Continue reading →

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Six new stem cell lines now publicly available

Posted: Published on June 15th, 2012

ScienceDaily (June 14, 2012) Six new human embryonic stem cell lines derived at the University of Michigan have just been placed on the U.S. National Institutes of Health's registry, making the cells available for federally-funded research. U-M now has a total of eight cell lines on the registry, including five that carry genetic mutations for serious diseases such as the severe bleeding disorder hemophilia B, the fatal brain disorder Huntington's disease and the heart condition called hypertrophic cardiomyopathy, which causes sudden death in athletes and others. Researchers at U-M and around the country can now begin using the stem cell lines to study the origins of these diseases and potential treatments. Two of the cell lines are believed to be the first in the world bearing that particular disease gene. The three U-M stem cell lines now in the registry that do not carry disease genes are also useful for general studies and as comparisons for stem cells with disease genes. In all, there are 163 stem cell lines in the federal registry, most of them without major disease genes. Each of the lines was derived from a cluster of about 30 cells removed from a donated five-day-old embryo roughly … Continue reading →

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ViaCyte Appoints Dr. Paul Laikind Chief Executive Officer

Posted: Published on June 15th, 2012

SAN DIEGO, June 15, 2012 /PRNewswire/ --ViaCyte, Inc. today announced the appointment of seasoned entrepreneur, Paul Laikind, Ph.D., as President & Chief Executive Officer. Allan Robins, Ph.D., who was serving as Acting CEO, will continue in his role as Vice President & Chief Technology Officer. ViaCyte is a leading pre-clinical company developing a novel cell therapy product for the treatment of insulin dependent diabetes. Dr. Laikind brings over 25 years of leadership experience in the biotechnology and life sciences industry to ViaCyte. He is a serial entrepreneur, who co-founded three San Diego companies, Gensia Pharmaceuticals Inc., Viagene Inc., and Metabasis Therapeutics Inc., serving in various executive positions including President and CEO. All three companies went public and were eventually acquired. Most recently, he served as Chief Business Officer and Senior Vice President of Business Development at the Sanford-Burnham Medical Research Institute. "Paul brings to ViaCyte a wealth of experience in managing new businesses based on highly innovative life sciences technologies," said Fred Middleton, Chairman of ViaCyte. "We are pleased to have him join to lead ViaCyte through our next phase of development in bringing our transformative stem cell therapy to patients with diabetes. We believe Paul's leadership and business development … Continue reading →

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Destined to live and die in pain

Posted: Published on June 15th, 2012

Destined to live and die in pain 12.06.2012 Wilma Stassen Morphine is a safe, effective and cheap treatment for pain, yet, many people dont have access to it, and in fact, many South Africans die in agonising pain because it is not made available to them. Pain, pain, pain. The last two weeks of that mans life was just pain from beginning to end, recalls Sister Delores Cano, a nurse at the Nightingale Hospice in De Aar in the Northern Cape. Cona had to stand by helplessly while a 49-year old cancer patient died in unbearable pain because the local health services refused to issue him with more morphine. Doctors are scared to prescribe morphine and we have to put up a big fight to get it for our patients, says Cona, a stout woman with a kind face who speaks pure Afrikaans with a charming Cape accent. And often when we get morphine, the doses isnt enough to cover the pain for long. When a patients disease has progressed to a certain point, some medical professionals are of the opinion that they have done all they could and then stop treatment, often because they dont want to spend any … Continue reading →

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South Africa: Destined to Live and Die in Pain

Posted: Published on June 15th, 2012

Many ill South Africans live and die suffering from unnecessary and excruciating pain. It is estimated that almost all HIV patients (96%) and more than two in three (70%) of cancer patients experience severe pain during the course of their disease because they do not have access to cheap and effective pain medication. Morphine is a safe, effective and cheap treatment for pain, yet, many people don't have access to it, and in fact, many South Africans die in agonising pain because it is not made available to them. "Pain, pain, pain. The last two weeks of that man's life was just pain from beginning to end," recalls Sister Delores Cano, a nurse at the Nightingale Hospice in De Aar in the Northern Cape. Cona had to stand by helplessly while a 49-year old cancer patient died in unbearable pain because the local health services refused to issue him with more morphine. "Doctors are scared to prescribe morphine and we have to put up a big fight to get it for our patients," says Cona, a stout woman with a kind face who speaks pure Afrikaans with a charming Cape accent. "And often when we get morphine, the doses isn't … Continue reading →

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A.M. Vitals: Crackdown on Illegal Online Drug Sales

Posted: Published on June 15th, 2012

By Stefanie Ilgenfritz Heres whats making health news this morning: Canadian Web Drug Pioneer Arrested (WSJ): In a sign of a stepped-up crackdown on the illegal pharmaceutical trade, U.S. authorities arrested Andrew Strempler, a pioneer of the Canadian Internet pharmacy industry, on charges related to the sale of foreign and counterfeit medicines, according to officials in Miami. FDA Warns Against Korean Seafood (WSJ): Regulators are urging stores and restaurants in the U.S. to stop selling imported Korean oysters, clams, mussels and some types of scallops because they may have been exposed to human fecal waste and are potentially contaminated with norovirus. How Well Do You Sleep? The Answer May Depend on Your Race (Time Healthland): At a meeting of the Associated Professional Sleep Societies in Boston, scientists report that the amount and quality of sleep people get vary across racial and ethnic lines. In one study, researchers found that blacks and Asians dont sleep as much as whites do, while another study showed that foreign-born Americans are less likely to report having sleep problems than those born in the U.S. Dialysis Companys Failure to Warn of Product Risk Draws Inquiry (NY Times): The FDA is investigating whether the nations largest … Continue reading →

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