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Manitoba Internet-drug pioneer arrested in Miami

Posted: Published on June 15th, 2012

Brandon Sun - ONLINE EDITION By: Gabrielle Giroday 15/06/2012 11:55 AM A Manitoba man and pioneer in the Internet pharmacy industry was arrested in Miami on charges of selling counterfeit medicines, a report says. The Wall Street Journal says 38-year-old Andrew Strempler appeared Thursday in a federal court in Miami. It says he could face up to 20 years in prison for each of the three charges against him, as well as a forfeiture of $95 million. A Miami Federal court clerk said Friday Strempler had been charged with one count of conspiracy to commit mail fraud, as well as two counts of mail fraud. The charges date from a period from January 2005 to June 2006, said the clerk. The Journal quotes a court clerk as saying that Strempler is expected to be arraigned next week. Strempler is an online pioneer who once ran the Manitoba-based online pharmacy, RxNorth. He later moved business to an island off the coast of Venezuela, called PharmaCheck. Read the original: Manitoba Internet-drug pioneer arrested in Miami … Continue reading →

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Manitoba Internet-drug pioneer Strempler arrested in Miami

Posted: Published on June 15th, 2012

Winnipeg Free Press - ONLINE EDITION By: Gabrielle Giroday Posted: 7:50 AM A Manitoba man and pioneer in the Internet pharmacy industry was arrested in Miami on charges of selling counterfeit medicines, a report says. The Wall Street Journal says 38-year-old Andrew Strempler appeared Thursday in a federal court in Miami. It says he could face up to 20 years in prison for each of the three charges against him, as well as a forfeiture of $95 million. A Miami Federal court clerk said Friday Strempler had been charged with one count of conspiracy to commit mail fraud, as well as two counts of mail fraud. The charges date from a period from January 2005 to June 2006, said the clerk. The Journal quotes a court clerk as saying that Strempler is expected to be arraigned next week. Strempler is an online pioneer who once ran the Manitoba-based online pharmacy, RxNorth. He later moved business to an island off the coast of Venezuela, called PharmaCheck. Read the original: Manitoba Internet-drug pioneer Strempler arrested in Miami … Continue reading →

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Plethora Solutions – Issue of Equity – Directors' Interest

Posted: Published on June 15th, 2012

15 June 2012 Plethora Solutions Holdings PLC ("Plethora" or the "Company") Issue of Equity - Directors' Interest Plethora Solutions Holdings plc (AIM: PLE), the UK-based speciality pharmaceutical company, announces that it has made the following share issues. First (OTC BB: FSTC.OB - news) , 140,000 shares have been issued to the pension fund of Ronald Openshaw, CEO, Plethora Solutions (LSE: PLE.L - news) , at 5p per share to satisfy liabilities up to 31 May 2012. Following this issue Mr Openshaw has a beneficial interest in 416,669 shares representing approximately 0.2% of the enlarged issued share capital of the Company. The Company and Mr Openshaw have agreed that on an ongoing basis it will satisfy his pension contributions on a quarterly basis through the issue of new ordinary shares issued at the closing mid-market price on the day before issue. Further issues will be made as soon as practicable following the end of each calendar quarter. The next issue will be made following the end of the September quarter. This arrangement will remain in place for a minimum of 12 months and may be terminated, thereafter, by either party following not less 3 months notice and provided that the Company … Continue reading →

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ViaCyte Appoints Dr. Paul Laikind Chief Executive Officer

Posted: Published on June 15th, 2012

SAN DIEGO, June 15, 2012 /PRNewswire/ --ViaCyte, Inc. today announced the appointment of seasoned entrepreneur, Paul Laikind, Ph.D., as President & Chief Executive Officer. Allan Robins, Ph.D., who was serving as Acting CEO, will continue in his role as Vice President & Chief Technology Officer. ViaCyte is a leading pre-clinical company developing a novel cell therapy product for the treatment of insulin dependent diabetes. Dr. Laikind brings over 25 years of leadership experience in the biotechnology and life sciences industry to ViaCyte. He is a serial entrepreneur, who co-founded three San Diego companies, Gensia Pharmaceuticals Inc., Viagene Inc., and Metabasis Therapeutics Inc., serving in various executive positions including President and CEO. All three companies went public and were eventually acquired. Most recently, he served as Chief Business Officer and Senior Vice President of Business Development at the Sanford-Burnham Medical Research Institute. "Paul brings to ViaCyte a wealth of experience in managing new businesses based on highly innovative life sciences technologies," said Fred Middleton, Chairman of ViaCyte. "We are pleased to have him join to lead ViaCyte through our next phase of development in bringing our transformative stem cell therapy to patients with diabetes. We believe Paul's leadership and business development … Continue reading →

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Cancer's next magic bullet may be magic shotgun

Posted: Published on June 15th, 2012

Public release date: 15-Jun-2012 [ | E-mail | Share ] Contact: Jason Socrates Bardi jason.bardi@ucsf.edu 415-502-6397 University of California - San Francisco A new approach to drug design, pioneered by a group of researchers at the University of California, San Francisco (UCSF) and Mt. Sinai, New York, promises to help identify future drugs to fight cancer and other diseases that will be more effective and have fewer side effects. Rather than seeking to find magic bulletschemicals that specifically attack one gene or protein involved in one particular part of a disease processthe new approach looks to find "magic shotguns" by sifting through the known universe of chemicals to find the few special molecules that broadly disrupt the whole diseases process. "We've always been looking for magic bullets," said Kevan Shokat, PhD, a Howard Hughes Medical Institute Investigator and the Chair of the Department of Cellular and Molecular Pharmacology at UCSF. "This is a magic shotgunit doesn't inhibit one target but a set of targetsand that gives us a much, much better ability to stop the cancer without causing as many side effects." Described in the June 7, 2012 issue of the journal Nature, the magic shotgun approach has already yielded … Continue reading →

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Wilshere's Failed Drugs Test Rumors: A Fan's Take

Posted: Published on June 15th, 2012

There's a lot time to talk in the off-season and people have Twitter, message boards and Facebook to feed their need to gossip and tittle-tattle; so, I wasn't really stunned last week when false rumors spread from a Twitter account alleging that Jack Wilshere had not played for Arsenal because he had failed a drugs test. Wilshere suffered a stress fracture in his ankle in pre-season for the 2011-12 season, as the injury worsened it prevented him from playing for the Gunners. He underwent surgery in September of last year. The ankle injury even deprived him the opportunity to travel to the Euros with England. It was a major setback for the 20-year-old midfielder and now he has this junk rumor to deal with. How does someone on Twitter know that Wilshire failed a drugs test or not? The allegation got Arsenal to make a swift response and a short statement in The Sun. How do we know the tweet didn't come from some Tottenham fan that lives in his mom's basement, whose hobbies include stuffing their face with Ho Hos and playing hours of Warcraft? The Arsenal statement said: "The rumored reason on social networks behind Jack's absence this … Continue reading →

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More Tantalizing Clues Oxytocin May Be An Effective Autism Treatment

Posted: Published on June 15th, 2012

In a preliminary presentation of new research, doctors said a nasal spray containing the hormone helped activate "social" regions of the brain. Oxytocin, the "mother-infant bonding hormone," holds even more promise for helping treat the social deficits that are often part of autism spectrum disorder (ASD). Where earlier work piqued interest in oxytocin as a possible treatment, a new study goes further to support its role in treating the disorder, which now affects one in 88 children born today, according to the CDC. In the new study, the authors conducted a double-blind placebo-controlled trial, the gold standard of scientific research. The team gave half of a group of children aged 7-18 a single dose of a nasal spray containing oxytocin. The other half of the group received a placebo - a nasal spray with no active ingredient in it. The brains of the children who had received the oxytocin showed that areas of the "social brain," were activated. These included the medial prefrontal cortex, the temporal parietal junction, the fusiform gyrus and the superior temporal sulcus, all areas involved in processing social information coming from sight, sounds, and cues from other people. Oxytocin is secreted in large amounts during and … Continue reading →

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Stroke patients 'healed' by controversial stem cell injections that have improved movement and allowed one to speak

Posted: Published on June 15th, 2012

By Fiona Macrae PUBLISHED: 19:48 EST, 14 June 2012 | UPDATED: 19:48 EST, 14 June 2012 The pioneering treatment could revolutionise stroke rehabilitation (picture posed by model) The first stroke patients to have a pioneering and controversial stem cell treatment have shown tantalising signs of improvement. The five men have seen improvements in their ability to move, and in one case, speak, after millions of stem cells from an aborted 12-week-old baby were injected into their brains up to 18 months ago. However, the treatment has provoked criticism from campaigners who say that the use of aborted tissue cannot be justified, whatever the benefits to the patient. The trial, spearheaded by Surrey-based biotech firm ReNeuron and carried out at Glasgows Southern General Hospital, was the first in the world to give brain cells to stroke patients. The treatment capitalises on the power of stem cells, dubbed master cells, which have the ability to multiply repeatedly and transform into other cell types, acting as a repair kit for the body. Experts cautioned that the work is at a very early stage, but added that even the smallest of improvements can make a huge difference to someone who has been robbed of … Continue reading →

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From high to healing

Posted: Published on June 15th, 2012

From high to healing - ecstasy could help Parkinson's sufferers. Photo: Viki Yemettas A decade after ecstasy was hailed for its ability to enhance treatment of Parkinson's disease, a WA scientist has managed to modify the drug, eliminating its harmful effects. The development means the illicit drug could after all be used to reduce the side-effects of the most common treatment, levodopa. Levodopa restores movement in Parkinson's patients but also causes jerky, involuntary movements commonly associated with the disease. Advertisement: Story continues below At the beginning of the century a former professional stuntman proved ecstasy could improve his treatment but doctors warned it had no therapeutic value because it affected users' moods and killed brain cells. University of WA Associate Professor Matthew Piggott said his team's research, in collaboration with experts in Toronto, had managed to dissociate the positive and negative effects of methylenedioxymethamphetamine (MDMA), commonly known as ecstasy. "By changing the structure of the drug we have a new compound structurally related to MDMA but ... not the other effects of MDMA that are well characterised and the reason why it's abused," Professor Piggott said. The new compound is called UWA-101 and trials on rats have shown it is … Continue reading →

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St. Michael's receives $700,000 FedDev grant to study how to prevent brain injury complications

Posted: Published on June 15th, 2012

Public release date: 15-Jun-2012 [ | E-mail | Share ] Contact: Leslie Shepherd shepherdl@smh.ca 416-864-6094 St. Michael's Hospital TORONTO, June 15, 2012St. Michael's Hospital has been awarded up to $700,000 from the Federal Economic Development Agency of Southern Ontario to investigate new treatments to prevent complications following certain brain injuries. The funding, to be administered by the Ontario Brain Institute, is part of an $11 million package announced by the federal government to help accelerate the commercialization of neurotechnologies. The FedDev funds will be matched by Edge Therapeutics, Inc., a biopharmaceutical company based in New Jersey. Edge and St. Michael's are exploring new ways of delivering nimodipine, an oral drug that has shown good results in preventing vasospasm, a major complication of aneurismal subarachnoid hemorrhage (bleeding in the area between the brain and the thin tissue that covers the brain). For two weeks following a subarachnoid hemorrhage, patients are susceptible to cerebral vasospasm, which limits blood flow to the brain and can cause ischemic strokes and additional tissue damage. Nimodipine inhibits calcium ion transfer into smooth muscle, thus preventing contraction of smooth vascular muscle in the brain. Subarachnoid hemorrhage affects 10 in 100,000 people in North America each year, or … Continue reading →

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