I am sure for the next few daysif not weeks and even yearsresearch out of Trinity College Dublin will be portrayed in the press and among some NGOs as "nanotechnology causes arthritis." Unfortunately, the story of the researchwhich was published in the journal Nanomedicineis a bit more complicated than that and the details will likely get lost in the furor that the initial headlines will generate. Basically, the researchers examined whether proteins when exposed to certain nanoparticles can change the amino acid arginine into the amino acid citrulline. This process known as post-translational citrullination of proteins has been linked to autoimmune diseases like rheumatoid arthritis. So maybe to avoid some confusion, it might be best to say from the outset that this research does not establish the risk of nanoparticles but only their potential hazard under very controlled (but unusual) circumstances. Further, despite what the press release may claim, I dont see how they have established much in the way of safety implications for the use and ultimate disposal of nanotechnology products and materials. Whenever I see a story about nanoparticles and toxicity, I immediately drag out my formula for understanding risk: Hazard x Exposure = Risk. When you consider … Continue reading
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