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New drugs, fresh hope for autism patients

Posted: Published on May 31st, 2012

CHICAGO Lynn and Neil Balter always dreaded stage productions at their son Jack's elementary school. When Jack was up there with the other performers, the noise, the lights, the crowd almost always got to him, and he would "start spinning," wandering around the stage or turning in circles, Lynn says. "It usually turned into an embarrassing situation," she adds. But at a dance performance at Jack's Scottsdale, Arizona, school last December, something was different. "He was half a beat behind in the dance, but he did the whole thing," Neil says. "He participated and took the bow with his class." Afterward, Jack's teacher greeted the Balters in tears. "I don't know what is going on with this kid, but there is this miracle happening and I have a different kid at school," she told the Balters. Jack, 9 years old, has autism. What his teacher didn't know is that Jack was taking part in a clinical trial for a drug aimed at overcoming some of the social impairment associated with autism, a spectrum of disorders that range from the social awkwardness and narrow interests seen in Asperger syndrome to severe communication and intellectual disabilities. For years the best that doctors … Continue reading

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Segal Announces New National Pharmacy Benefits Practice Leader

Posted: Published on May 31st, 2012

NEW YORK--(BUSINESS WIRE)-- Joseph A. LoCicero, President & CEO of The Segal Company has announced that Ritu Malhotra, PharmD, Vice President and Clinical Pharmacy Consultant, has been named National Pharmacy Benefits Practice Leader. Mr. LoCicero said, As National Pharmacy Benefit Practice Leader, Ritus role is to be a thought leader on prescription drug benefit plan design, cost savings strategies, clinical management strategies, practice development and market trends. Her experience in integrating clinical knowledge into managed care settings has been especially effective for our clients. We are looking forward to her leading our PBM technical team and the Rx consulting group. Dr. Malhotra will also support marketing and sales efforts and serve as the primary spokesperson on Rx- related matters. She will continue to work directly with clients on pharmacy benefit programs. Dr. Malhotra holds a Doctor of Pharmacy from the University of the Sciences, Philadelphia College of Pharmacy, and a BA in Biology from Lehigh University (Bethlehem, PA). She is an active member of the Academy of Managed Care Pharmacy (AMCP). Dr. Malhotra works out of the firms Chicago office and reports to Ed Kaplan, Senior Vice President and National Health Practice Leader. The Segal Company (www.segalco.com) is an independent, … Continue reading

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Diplomat Specialty Pharmacy CEO Phil Hagerman to Participate With White House Business Council and Business Forward

Posted: Published on May 31st, 2012

FLINT, Mich., May 31, 2012 /PRNewswire/ -- Diplomat Specialty Pharmacy, the nation's largest, privately owned specialty pharmacy, announced today that CEO Phil Hagerman has received an invitation from the White House Business Council and Business Forward to attend a one-day forum on jobs and the economy. The White House Business Council will host Mr. Hagerman and other business leaders from Michigan on June 1 at the White House for an interactive dialogue about what is working in Michigan and how the private sector and government can collaborate more effectively to foster greater opportunity, innovation, job creation and, in the words of President Obama, "create an American economy that's built to last." "I am extremely honored to represent Diplomat, the state of Michigan and also Flint's business community," said Hagerman. "Diplomat's continued growth has positioned us to be part of the Michigan delegation. In January of 2010 we had 360 employees. Today, as the nation's 4th largest specialty pharmacy, we employ over 700 people and we're hiring every day." The forum at the White House will cover a range of topics as they relate to Michigan business communities. Over the past year, the White House Business Council has hosted meetings with … Continue reading

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NeoStem to Present at Six Conferences in June

Posted: Published on May 31st, 2012

NEW YORK, May 31, 2012 (GLOBE NEWSWIRE) -- NeoStem, Inc. (NYSE Amex:NBS) ("NeoStem" or the "Company"), an international biopharmaceutical company focused on cell based therapies, announced today that Company management will present at six conferences in June. International Society for Cellular Therapy Annual Meeting National Investment Banking Association Conference International Society for Stem Cell Research 10th Annual Meeting The Biotechnology Industry Organization (BIO) International Conference Alliance for Regenerative Medicine -- Clinical Outlooks for Regenerative Medicine 2012 Marcum's Inaugural MicroCap Conference About NeoStem, Inc. NeoStem, Inc. ("NeoStem") is a leader in the development and manufacture of cell therapies. NeoStem has a strategic combination of revenues, including that which is derived from the contract manufacturing services performed by Progenitor Cell Therapy, LLC, a NeoStem company. That manufacturing base is one of the few cGMP facilities available for contracting in the burgeoning cell therapy industry, and it is the combination of PCT's core expertise in manufacturing and NeoStem's extensive research capabilities that positions the company as a leader in cell therapy development. Amorcyte, LLC, also a NeoStem company, is developing a cell therapy for the treatment of cardiovascular disease. Amorcyte's lead compound, AMR-001, represents NeoStem's most clinically advanced therapeutic and is enrolling patients … Continue reading

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Spectrum Pharmaceuticals Highlights Seven Abstracts of Clinical Data at the 2012 American Society of Clinical Oncology …

Posted: Published on May 31st, 2012

HENDERSON, Nev.--(BUSINESS WIRE)-- Spectrum Pharmaceuticals (SPPI), a biotechnology company with fully integrated commercial and drug development operations with a primary focus in oncology and hematology, today announced key presentations of clinical data, including five ZEVALIN-related poster presentations, as well as a poster presentation and one e-abstract publication of clinical data for belinostat, at the American Society of Clinical Oncology (ASCO) Annual Meeting, being held in Chicago, Illinois, from June 1-5, 2012. For more information about the ASCO annual meeting and for a complete list of abstracts, please refer to the conference Web site at http://abstract.asco.org/. The following are key ZEVALIN-related abstracts being presented at the ASCO conference: Monday June 4, 2012, 1:15 PM - 5:15 PM Central Time First Author S Hall A2 S Hall A2 S Hall A2 S Hall A2 See the original post here: Spectrum Pharmaceuticals Highlights Seven Abstracts of Clinical Data at the 2012 American Society of Clinical Oncology ... … Continue reading

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Prochymal approval makes Canada first country to OK stem cell therapy

Posted: Published on May 31st, 2012

Toni Clarke BOSTON Globe and Mail Update Published Friday, May. 18, 2012 12:38PM EDT Last updated Friday, May. 18, 2012 12:56PM EDT Osiris Therapeutics Inc. OSIR-Q said on Thursday that Canadian health regulators have approved its treatment for acute graft-versus host disease in children, making it the first stem cell drug to be approved for a systemic disease anywhere in the world. Osiris shares rose 14 per cent to $6.00 in extended trading after the news was announced. Graft versus host disease (GvHD) is a potentially deadly complication from a bone marrow transplant, when newly implanted cells attack the patient's body. Symptoms range from abdominal pain and skin rash to hair loss, hepatitis, lung and digestive tract disorders, jaundice and vomiting. The disease kills up to 80 per cent of children affected, Osiris said. To date there have been no approved treatments for the disease. Canadian authorities approved the therapy, Prochymal, for use in children who have failed to respond to steroids. Prochymal was approved with the condition that Osiris carry out further testing after it reaches the market. C. Randal Mills, the company's chief executive, said in an interview that could take three to four years. Some investment analysts … Continue reading

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Gaborone could have stem cell storage facility this year

Posted: Published on May 31st, 2012

Gaborone could have stem cell storage facility this year LAWRENCE SERETSE Correspondent Speaking to Mmegi this week, Mngqibisa said Parliament was set to pave the way for the facility by means of legislation in July and that Cryo-Save intended approaching government about storing stem cells for every Motswana. "Stem cells are the basic building blocks of our bodies and are often referred to as 'master cells,'" she said. "And because stem cells have the potential to become almost any other cell in the body, stem cell therapies are the way of the future." Stem cell treatment is applied to over 70 diseases and disorders, among them leukemia, lymphoma, blood cancers and bone marrow disorders like aplastic anaemia and sickle cell disease. Mngqibisa said patients requiring a haemopoietic stem transplant will receive cells from one or three sources of bone marrow, circulating blood or umbilical cord blood. "It is much easier to match transplant patients with immune naive cord blood stem cells than with the other sources of stem cells," she explained. "Umbilical cord blood stem cells are the most naive stem cells, hence they are best harvested from the baby at birth before they are exposed to infections and immune … Continue reading

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Osiris rises on nod for wound treatment reimbursement

Posted: Published on May 31st, 2012

(Reuters) - Shares of Osiris Therapeutics Inc rose 15 percent on Wednesday, after U.S. health regulators said the stem-cell technology company's wound treatment was eligible for reimbursement when used in hospitals in out-patient settings or in ambulances. The Center for Medicare & Medicaid Services also cleared the pathway for a permanent reimbursement code for Grafix, Osiris's wound-care matrix containing stem cells, on Tuesday. A permanent code makes reimbursement for the treatment faster and easier, thus increasing the chances of a physician prescribing it. Osiris said if the permanent reimbursement code for Grafix was approved, it could become effective from January next year. First-quarter revenue from the company's biosurgery products - Grafix and a bone matrix product called Ovation - have risen about 50 percent to $1.14 million. Shares of the Columbia, Maryland-based company were trading up 8 percent at $6.98 Wednesday morning on the Nasdaq. They jumped to $7.49 earlier in the session. (Reporting by Vidya P L Nathan in Bangalore; Editing by Don Sebastian) (This story was corrected in paragraph 2 to say the regulator was Center for Medicare & Medicaid Services, not the U.S. FDA) Read more: Osiris rises on nod for wound treatment reimbursement … Continue reading

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29 Johns Hopkins stem cell researchers awarded funding

Posted: Published on May 31st, 2012

Public release date: 30-May-2012 [ | E-mail | Share ] Contact: Vanessa McMains vmcmain1@jhmi.edu 410-502-9410 Johns Hopkins Medical Institutions This year the Maryland Stem Cell Research Fund awarded 29 of 40 grants to Johns Hopkins researchers for the study of stem cell metabolism and regulation, the creation of new cell models for human diseases such as schizophrenia and Rett syndrome, which previously could be studied only in animals, and the development of new potential therapies. Researchers whose preliminary data promised greater discoveries were awarded Investigator-Initiated grants. Jeff Bulte, Ph.D., professor of radiology, biomedical engineering and chemical and biomolecular engineering and a member of the Institute for Cell Engineering, hopes to develop a cell therapy for treatment of type 1 diabetes an autoimmune disorder in which the immune system kills the insulin-producing cells that help regulate blood sugar. By developing cloaked stem and insulin-producing cells that can evade immune system detection, Bulte and his team hope to replace damaged cells and restore insulin levels in patients. Grants were awarded to: Several Johns Hopkins investigators were awarded Exploratory grants for researchers either new to the stem cell field or with untested but promising new ideas. Miroslaw Janowski , M.D., Ph.D., a research … Continue reading

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NeoStem to Present at Six Conferences in June

Posted: Published on May 31st, 2012

NEW YORK, May 31, 2012 (GLOBE NEWSWIRE) -- NeoStem, Inc. (NYSE Amex:NBS) ("NeoStem" or the "Company"), an international biopharmaceutical company focused on cell based therapies, announced today that Company management will present at six conferences in June. International Society for Cellular Therapy Annual Meeting National Investment Banking Association Conference International Society for Stem Cell Research 10th Annual Meeting The Biotechnology Industry Organization (BIO) International Conference Alliance for Regenerative Medicine -- Clinical Outlooks for Regenerative Medicine 2012 Marcum's Inaugural MicroCap Conference About NeoStem, Inc. NeoStem, Inc. ("NeoStem") is a leader in the development and manufacture of cell therapies. NeoStem has a strategic combination of revenues, including that which is derived from the contract manufacturing services performed by Progenitor Cell Therapy, LLC, a NeoStem company. That manufacturing base is one of the few cGMP facilities available for contracting in the burgeoning cell therapy industry, and it is the combination of PCT's core expertise in manufacturing and NeoStem's extensive research capabilities that positions the company as a leader in cell therapy development. Amorcyte, LLC, also a NeoStem company, is developing a cell therapy for the treatment of cardiovascular disease. Amorcyte's lead compound, AMR-001, represents NeoStem's most clinically advanced therapeutic and is enrolling patients … Continue reading

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