By Rick Nauert PhD Senior News Editor Reviewed by John M. Grohol, Psy.D. on May 3, 2012 Parkinsons disease is an insidious disorder affecting movement and cognition for over one million Americans. New research has identified a method that stops and even prevents the progression of Parkinsons in mice and holds out hope for a preventative therapy. Parkinsons is defined by a gradual loss of nerve cells of neurons that produce a chemical called dopamine. Dopamine is essential for normal function of muscles and other body organs. Researchers have learned that changes in a gene known as DJ-1 also leads to an accelerated loss of dopaminergic neurons and results in the onset of Parkinsons symptoms at a young age. Although people naturally lose dopamine-producing neurons as part of the aging process, Parkinsons patients experience a rapid loss of these neurons from the onset of the disease, leading to much more drastic deficiencies in dopamine than the average person. The ability to modify the activity of DJ-1 could change the progress of the disease, said Dr. Nirit Lev, a researcher at Tel Aviv University. Working in collaboration with Profs. Dani Offen and Eldad Melamed, she has now developed a peptide which … Continue reading
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