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Wheelchair breakdowns becoming more common, reports AJPM&R

Posted: Published on May 3rd, 2012

Public release date: 2-May-2012 [ | E-mail | Share ] Contact: Connie Hughes Connie.Hughes@wolterskluwer.com 646-674-6348 Wolters Kluwer Health Philadelphia, Pa. (May 2, 2012) Wheelchair users with spinal cord injury (SCI) report very high rates of wheelchair breakdownsand the problem is getting worse, suggests a study in American Journal of Physical Medicine & Rehabilitation (AJPM&R), the official journal of the Association of Academic Physiatrists, AJPM&R is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. The study found that over 50 percent of wheelchair users experienced a breakdown in a six-month period, up from a previous report. "It is possible that this increase in the number of repairs is the result of a decrease in wheelchair quality resulting from changes in reimbursement policies and a lack of enforcement of standards testing," write the researchers, led by Dr Michael Boninger of University of Pittsburgh's Department of Physical Medicine and Rehabilitation. They also found a significant increase in wheelchair breakdowns causing health and safety consequences. For People with SCI, Wheelchair Breakdowns Becoming More Frequent Dr Boninger and colleagues analyzed data from an ongoing survey study of more than 700 individuals with SCI who used wheelchairs at least 40 hours per … Continue reading

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Freezing Parkinson's in its tracks

Posted: Published on May 3rd, 2012

Public release date: 2-May-2012 [ | E-mail | Share ] Contact: George Hunka ghunka@aftau.org 212-742-9070 American Friends of Tel Aviv University Parkinson's disease, a disorder which affects movement and cognition, affects over a million Americans, including actor Michael J. Fox, who first brought it to the attention of many TV-watching Americans. It's characterized by a gradual loss of neurons that produce dopamine. Mutations in the gene known as DJ-1 lead to accelerated loss of dopaminergic neurons and result in the onset of Parkinson's symptoms at a young age. The ability to modify the activity of DJ-1 could change the progress of the disease, says Dr. Nirit Lev, a researcher at Tel Aviv University's Sackler Faculty of Medicine and a movement disorders specialist at Rabin Medical Center. Working in collaboration with Profs. Dani Offen and Eldad Melamed, Dr. Lev has now developed a peptide which mimics DJ-1's normal function, thereby protecting dopamine- producing neurons. What's more, the peptide can be easily delivered by daily injections or absorbed into the skin through an adhesive patch. Based on a short protein derived from DJ-1 itself, the peptide has been shown to freeze neurodegeneration in its tracks, reducing problems with mobility and leading to … Continue reading

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RBCC Target Amarantus BioSciences Reports Positive Pre-Clinical Results of Parkinson’s Treatment

Posted: Published on May 3rd, 2012

NOKOMIS, Fla.--(BUSINESS WIRE)-- Rainbow BioSciences, LLC, the biotech subsidiary of Rainbow Coral Corp. (OTCBB: RBCC.OB - News), announced today that its current joint venture target, Amarantus BioSciences, Inc., has achieved positive results in a pre-clinical experiment demonstrating the potential of its new Parkinsons disease therapy currently in development. Amarantus is the developer of MANF, a first-in-class, disease-modifying therapeutic protein that addresses an underlying form of cell death known as apoptosis. The experiments conducted last year were funded by a grant from the Michael J. Fox Foundation, and the results showed that MANF significantly reduces the behavioral deficits caused by the neurotoxin 6-OHDA in a standard animal model of Parkinsons disease. These results are even more significant because they showed that MANF compares favorably with a competing disease-modifying treatment called GDNF; a protein Amgen previously spent over $200M developing now entering Phase 2 clinical trials at Medgenesis Therapeutix. MANF has a mechanism of action that could have an impact on a larger population of Parkinsons patients than GDNF. Moreover, the amount of money that will be required for MANFs development will be significantly less than has been spent on GDNF to date. This is primarily because Amarantus has been able to … Continue reading

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Medics mistook brain bleed for drunkenness, pair say

Posted: Published on May 3rd, 2012

Alex Cottier. Alex Cottier (21), of Arrowtown, was at the national rugby sevens tournament in Queenstown in January with his mates when he vomited and collapsed. He and his mother, Vanessa, want to know why the hospital "got it wrong", want a review of the hospital process and an assurance changes will be made. "I want them to acknowledge they stuffed up. I want them to learn from their mistakes," Mrs Cottier said yesterday. Mr Cottier's illness was caused not by the four standard beers he had drunk that afternoon but by a rare and potentially fatal brain bleed - an arteriovenous malformation. It took more than 40 minutes to get him to hospital in Frankton after medical staff at the tournament allegedly assumed he was very drunk. The mother and son say the medical process had been drawn out further by four hospital staff who also assumed his state was alcohol-related. "I lay in Queenstown Hospital with all of them thinking I was drunk, until about 3pm the next day." Only when hospital staff were approached by a nurse who had seen the incident the day before did they concede it was more than just a hangover, and he … Continue reading

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Junior Seau: Apparent suicide follows deaths of athletes with brain trauma

Posted: Published on May 3rd, 2012

Former NFL star Junior Seaus death by apparent self-inflicted gunshot wound follows a pattern of suicides by other high-profile football players who suffered from long-term effects of repeated brain injury. That list of players includes Andre Waters of the Philadelphia Eagles and Terry Long of the Pittsburgh Steelers. And just last year, former Chicago Bears player Dave Duerson shot himself in the chest, but not before requesting that his brain be donated to science so that researchers could study the long-term effects caused by concussion and other repeated brain injuries. Seau also suffered a gunshot wound to the chest, rather than the head. The former Pro Bowler, who was 43, was found by his girlfriend at his home Wednesday. For Seau, there may have been recent warning signs that all was not well, according to the San Diego Union-Tribune. In October 2010, Seaus car plunged 30 feet off a coastal road in Carlsbad. He reportedly told police that he had fallen asleep while driving. The accident occurred hours after he was released from jail after being arrested on suspicion of domestic violence. His 25-year-old girlfriend did not require medical treatment, and Seau was never charged in the incident. The news … Continue reading

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UQ turns red to raise awareness of MS

Posted: Published on May 3rd, 2012

The Forgan Smith building at the UQ St Lucia campus is lit up red in support of MS Awareness Month. UQ today switches on the red floodlights on the northern side of the Forgan Smith Building in the middle of the Great Court, and will leave them on between 6pm and 11pm every night for the duration of MS Awareness Month, to help raise awareness of the disease. Multiple Sclerosis (MS) is the most common chronic neurological condition amongst young Australian adults today -- a disease that attacks a person's brain and spinal cord causing irreparable damage. More than 21,000 Australians are living with it and, while there is no known cure, researchers at the Queensland Brain Institute (QBI) and the UQ Centre for Clinical Research (UQCCR) are working to find treatments and learn more. Dr Judith Greer, an expert in MS at UQCCR, said the centre was working on understanding more about several aspects of MS. This includes studying genes that appear to be related to development of chronic progressive MS, trying to understand why pregnancy has both short and long-term beneficial effects for women with MS and looking at the role of EBV (the virus that causes glandular … Continue reading

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Walkers wanted

Posted: Published on May 3rd, 2012

Select a Publication: N E W S P A P E R S ---------------------------------------------- ---Alberta--- Airdrie - Airdrie Echo Banff - Banff Crag and Canyon Beaumont - Beaumont News Calgary - The Calgary Sun Camrose - Camrose Canadian Canmore - Canmore Leader Central Alberta - County Market Cochrane - Cochrane Times Cold Lake - Cold Lake Sun Crowsnest Pass - Crowsnest Pass Promoter Devon - Dispatch News Drayton - Drayton Valley Western Review Edmonton - Edmonton Examiner Edmonton - The Edmonton Sun Edson - Edson Leader Fairview - Fairview Post Fort McMurray - Fort McMurray Today Fort Saskatchewan - Fort Saskatchewan Record Grande Prairie - Daily Herald Tribune Hanna - Hanna Herald High River - High River Times Hinton - Hinton Parklander Lacombe - Lacombe Globe Leduc - Leduc Representative Lloydminster - Meridian Booster Mayerthorpe - Mayerthorpe Freelancer Nanton - Nanton News Peace Country - Peace Country Sun Peace River - Peace River Record Gazette Pincher Creek - Pincher Creek Echo Sherwood Park - Sherwood Park News Spruce Grove - Spruce Grove Examiner Stony Plain - Stony Plain Reporter Strathmore - Strathmore Standard Vermilion - Vermilion Standard Vulcan - Vulcan Advocate Wetaskiwin - Wetaskiwin Times Whitecourt - Whitecourt Star ---Manitoba--- … Continue reading

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MS questions and answers

Posted: Published on May 3rd, 2012

The Elk Grove MS Group will be hosting the number one authority in Multiple Sclerosis (MS) research in northern California, Dr. John Schaefer. He is a neurologist and the director of the Mercy Multiple Sclerosis Center in Carmichael. He earned his MD from the University of Chicagos Pritzker School of Medicine His neurology residency was conducted at the University of California at San Francisco. In addition, Schaefer is the Assistant Clinical Professor of Neurology at the University of California, Davis. He has written extensively on the topics of new treatments for MS, formulary decisions, patient adherence, and the costs of treatment for MS.Schaefer volunteers and serves the MS community at the Northern CA Chapter of the National MS Society. He is on the Professional Advisory Committee and is chair ofthe Central Valley location. He is also on the Chapter Board of Trustees. Joining Dr. Schaefer will be Edie Happs, a Certified Multiple Sclerosis Nurse and a certified rehabilitation nurse. She has focused her interest in Neuro- rehabilitation for the past10 years.She is now the MS nurse at Mercy MS Center in Carmichael. Sheis working withDr. Schaefer and Dr. KarstenDengel. They will present the North American Education Program, Working for Me … Continue reading

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New MS drug shows promise

Posted: Published on May 3rd, 2012

Rachelle Reagan was diagnosed four years ago with multiple sclerosis, which destroys myelin, a protective sheath that surrounds neurons. There is no cure for the auto-immune disease which is marked by flare-ups that have a cumulative, damaging effect on the body. Reagan, 35, of Herrin, Ill., has had three flare-ups. So she was excited to recently learn that her physician, Dr. Florian Thomas, professor of neurology and psychiatry at St. Louis University School of Medicine, will be taking part in studying a new drug, Teriflunomide. It reduced the number of new brain lesions in people with MS in earlier studies, and as a bonus, it comes in pill form. Most existing treatments require injections or infusions. The hope is that Teriflunomide will also reduce the frequency of flare-ups. Each year, about 10,000 people nationwide are diagnosed with multiple sclerosis. About 400,000 are living with the disease today. Reagan's left eye went blind during one flare-up when her immune system attacked the myelin surrounding her optic nerve cells. She estimates that 90 percent of her sight came back, but her vision is not as good as before. She still has problems controlling her legs since another flare-up attacked the myelin surrounding … Continue reading

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Hamilton Thorne Receives FDA Clearance on Its Multi-Pulse Software for Clinical Applications

Posted: Published on May 3rd, 2012

BEVERLY, MA and TORONTO, ON--(Marketwire -05/02/12)- Hamilton Thorne Ltd. (HTL.V - News), a leading provider of precision laser devices and advanced image analysis systems for the fertility, stem cell and developmental biology research markets, today announced that the Company's Multi-Pulse software has received FDA clearance for performing embryo biopsy in clinical settings. The Multi-Pulse software will come standard with Hamilton Thorne's best-in-class LYKOS clinical laser system and as an option on the legacy ZILOS-tk system in certain markets. The Multi-Pulse feature provides rapid, repeated firing of the laser to facilitate removal of cells from an embryo during the trophectoderm biopsy process. Trophectoderm biopsy is considered one of the best methods used to remove cells from the embryos of patients undergoing pre-implantation genetic diagnosis (PGD) to screen for genetic disease or aneuploidy. Prior to release of the Multi-pulse software, individual laser shots were required to weaken or break the junctions between the trophectoderm cells so that they can be aspirated into the biopsy micropipette. The significant advantage of Multi-Pulse is that one press of the remote footswitch initiates multiple laser pulses in rapid succession for fast and easy cell separation, thereby limiting the amount of time the embryo spends outside the … Continue reading

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