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Matt Dunigan is a Voice of Injury Prevention (VIP) for Concussion with ThinkFirst Canada:

Posted: Published on April 29th, 2012

Brain Injury Prevention in Team Sports in Canada TORONTO, April 28, 2012 /PRNewswire/ - ThinkFirst Pensez d'Abord Canada hosts a free lecture and workshop with keynote speaker Matt Dunigan. "ThinkFirst Canada is honored to have Matt Dunigan speaking up for child and youth health in team sport. Canada can and must do a better job at protecting our greatest resource, our children, by reducing the burden of head and brain injuries like concussion" said Rebecca Nesdale-Tucker, Executive Director and CEO, ThinkFirst-Pensez d'Abord Canada. Matt Dunigan is a sports concussion survivor and is emerging as an active injury prevention advocate, encouraging the need for concussion awareness. "The more we can educate ourselves in all aspects relating to concussions, including recognition, awareness, prevention and the proper protocols for back to play the better all sport will be. Parents, coaches, officials and society in general must take action in becoming more involved in dealing with concussions in sport" said Dunigan "Coaches and parents must be educated so they can appropriately intervene and protect the kids from themselves. The kids' innately are under tremendous pressures to produce and win in today's sporting world and often times can and will be their own worst enemy, … Continue reading →

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Bonnie and Ken Shockey encourage cancer patients to research Low Dose Naltrexone

Posted: Published on April 29th, 2012

Low Dose Naltrexone (LDN) was not originally intended to be a cancer treatment but one local couple encourages everyone with cancer to do their research on this drug. Bonnie and Ken Shockey both use LDN, but for very different reasons. Bonnie takes the drug to treat multiple sclerosis (MS), but Ken began taking it when he was diagnosed with prostate cancer. Both Ken and Bonnie have had positive results with the drug and hope one day it will be added to the list of options for treating different cancers. In laboratory studies, LDN stopped the growth of new cancer cells, but did not kill the cancer. Started with MS Bonnie was diagnosed with MS in 2007 and was on a traditional Federal Food and Drug Adminstration approved treatment, until having a severe allergic reaction to the protein in the drug. Shockey started researching at her neurologists suggestion and came across LDN as a possible treatment for MS. She started taking LDN in April of 2009, seeing results after just five days. It literally reversed some of the MS symptoms I had had for several decades, she said. Kens diagnosis In 2010, Ken was diagnosed with an aggressive, advanced form of … Continue reading →

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U-M stem-cell line gets national registry go-ahead

Posted: Published on April 29th, 2012

A second human embryonic stem-cell line derived at the University of Michigan has been accepted on the U.S. National Institutes of Health registry, making the line available for federally funded research and possibly bringing science a step closer to understanding Charcot-Marie-Tooth disease. The hereditary neurological disorder is characterized by muscle degeneration in the foot, lower leg and hand. The line, known as UM11-1PGD, was derived from a cluster of about 30 cells that had been removed from a donated 5-day-old embryo created for reproductive purposes. The cells were found to carry the gene defect responsible for the disease, also known as CMT. Because the stem-cell line carries the unique characteristics of the disease, researchers can use it to study the disease progression. That, in turn, may lead to screening techniques and even a cure. Like the first line, UM11-1PGD was developed by Gary Smith, codirector of the U-M Consortium for Stem Cell Therapies at the A. Alfred Taubman Medical Research Institute. Several other disease-specific lines have been submitted to NIH and are awaiting approval. The first accepted line, which is believed to be disease-free, was accepted to the registry in February. Contact Robin Erb: 313-222-2708 or rerb@freepress.com Continue reading here: … Continue reading →

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Teen's rare illness provides insight for doctors

Posted: Published on April 29th, 2012

When he was 3 years old and falling behind in his childhood development, doctors diagnosed Jonathan Oliphint with a rare genetic disease. There was a known treatment for the disease, in which the body produces an excess amount of ammonia, and doctors at Texas Children's Hospital soon began giving the boy a critical amino acid, arginine, his body was not making. It was a classic case of the power of the emerging science of genetic medicine in which doctors could pinpoint the genetic causes of disease, and devise successful treatments. That was the late 1990s, when genetics was a simpler science. Problems return The problem is, as scientists were discovering that the Human Genome Project and its elucidation of humanity's basic DNA would not immediately lead to medical breakthroughs, Oliphint started getting sick again. He started having high blood pressure. By the time he was 15, half a dozen blood pressure medicines had failed, and Oliphint was in the ICU with an enlarged heart. "They just couldn't get it under control," said the boy's mother, Jamie Oliphint. "It was scary. We didn't know what was going to happen." As Oliphint's blood pressure problems increased, scientists were rewriting our understanding of … Continue reading →

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Moffitt researcher awarded GE grant to develop tool to detect breast cancer metastasis genetic risks

Posted: Published on April 29th, 2012

Public release date: 27-Apr-2012 [ | E-mail | Share ] Contact: Patty Kim patty.kim@moffitt.org 813-745-7322 H. Lee Moffitt Cancer Center & Research Institute M. Catherine Lee, M.D., breast cancer researcher and assistant member at Moffitt Cancer Center, has received a $100,000 grant from General Electric's $100 million healthymagination Challenge to develop genetic tools to investigate an individual's genetic makeup to determine if they are predisposed to develop or resist breast cancer metastasis. GE's healthymagination grant awarding initiative focuses on "finding new ideas that accelerate innovation in early diagnosis, patient stratification, and the personalized treatment of breast cancer." Lee's successful proposal, "Heritable Markers of Metastasis in Patients Diagnosed with Breast Cancer," was based on what Lee describes as "significant evidence for specific genetic variations associated with an increased risk of cancer metastasis." According to Lee, the tumor in breast cancer is not the lethal element. Rather, it is the development and progression of breast cancer to other organs - called metastasis - that determines outcomes and survival. A number of genes and variations of those genes involved in the development of metastatic breast cancer have been identified. Metastatic breast cancer is deadly. In 2011, an estimated 230,430 women in the United … Continue reading →

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In saving teen, docs find "simple" genetic diseases not so simple

Posted: Published on April 29th, 2012

When he was 3 years old and falling behind in his childhood development, doctors diagnosed Jonathan Oliphint with a rare genetic disease. There was a known treatment for the disease, in which the body produces an excess amount of ammonia, and doctors at Texas Children's Hospital soon began giving the boy a critical amino acid, arginine, his body was not making. It was a classic case of the power of the emerging science of genetic medicine in which doctors could pinpoint the genetic causes of disease, and devise successful treatments. That was the late 1990s, when genetics was a simpler science. Problems return The problem is, as scientists were discovering that the Human Genome Project and its elucidation of humanity's basic DNA would not immediately lead to medical breakthroughs, Oliphint started getting sick again. He started having high blood pressure. By the time he was 15, half a dozen blood pressure medicines had failed, and Oliphint was in the ICU with an enlarged heart. "They just couldn't get it under control," said the boy's mother, Jamie Oliphint. "It was scary. We didn't know what was going to happen." As Oliphint's blood pressure problems increased, scientists were rewriting our understanding of … Continue reading →

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Stem cell division to evaluate clinical trials

Posted: Published on April 29th, 2012

Home Calcutta News.Net Friday 27th April, 2012 The Directorate General of Health Services has established a stem cell division to evaluate proposals concerning stem cell research, Health and Family Welfare Minister Ghulam Nabi Azad said here Friday. Speaking in the Lok Sabha, Azad said the stem cell division was established within the Biological Division in Central Drugs Standard Control Organisation for the internal evaluation of all proposals, including stem cell concerning with clinical trial and marketing authorisation. "Till recently, there was no mechanism in place to take note of the cases violating these guidelines or take action against the agencies found violating these guidelines," said Azad. The Indian Council of Medical Research and the Department of Biotechnology have jointly formulated guidelines for stem cell research and therapy to help experts and scientists working in the field conduct research responsibly and ethically sensitive manner. However, in view of the recent development in the field, the guidelines will be revised this year. Read this article: Stem cell division to evaluate clinical trials … Continue reading →

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Bellevue doctor tests stem-cell cream as anti-aging therapy

Posted: Published on April 29th, 2012

by JEAN ENERSEN / KING 5 News KING5.com Posted on April 27, 2012 at 11:01 PM A Bellevue doctor is one of only two researchers in the country testing stem cells as an anti-aging treatment. Working with volunteer patients, Dr. Fredric Stern extracts stem cells with a liposuction-like procedure. The cells are then mixed with a special medium. "Half is saved cyrogenically for future use and the other half is shipped to the laboratory in Arizona where on that end the stem cells are grown further," Stern said. The end product goes into a cream called tropoelastin. The hope is that high concentrations of a patient's own stem cells in the cream will boost the skink's ability to repair itself. If the eye cream proves successful in the eight-week study, the company will also offer a facial cream. Both could be available within a few months. Stern said he expects the price to be comparable to high-end cosmetic products that typically cost hundreds of dollars. Stern said the skin treatment is just the beginning. He said wound care is another possible use. Read more: Bellevue doctor tests stem-cell cream as anti-aging therapy … Continue reading →

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Scientists Have Found a Way to Regenerate Muscle Tissue After a Heart Attack [Medicine]

Posted: Published on April 27th, 2012

There could be a path to a simpler recovery after a heart attack. Duke University Medical Center scientists have discovered a way to turn the scar tissue that forms after cardiac arrest into healthy muscle tissue, which would make a stem cell transplant unnecessary. To achieve this, researchers introduced microRNA to scar tissue cells in a living mouse. These hardened cells, called fibroblasts, develop as a result of a heart attack, and impede the organ's ability to pump blood. The microRNAs, which are molecules that govern the activity of several genes, were able to manipulate the fibroblasts to transform into cells that looked like cardiomyocytes, which comprise heart muscle. The results of their study have been published in the journal Circulation Research. While further exploration is required, the find is promising for the millions of people in the U.S. that suffer from heart disease, the leading cause of death in this country. But it has application beyond that. If it works for the heart, theoretically it would help regenerate tissues in the brain, the kidneys, and other organs. Now that this cell reversal technique has proven successful, researchers plan to test it with larger animals. If it works, they'll try … Continue reading →

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Growing up as a neural stem cell: The importance of clinging together and then letting go

Posted: Published on April 26th, 2012

Public release date: 25-Apr-2012 [ | E-mail | Share ] Contact: Kim Irwin kirwin@mednet.ucla.edu 310-206-2805 University of California - Los Angeles Health Sciences Can one feel too attached? Does one need to let go to mature? Neural stem cells have this problem, too. As immature cells, neural stem cells must stick together in a protected environment called a niche in order to divide so they can make all of the cells that populate the nervous system. But when it's time to mature, or differentiate, the neural stem cells must stop dividing, detach from their neighbors and migrate to where they are needed to form the circuits necessary for humans to think, feel and interact with the world. Now, stem cell researchers at UCLA have identified new components of the genetic pathway that controls the adhesive properties and proliferation of neural stem cells and the formation of neurons in early development. The finding by scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA could be important because errors in this pathway can lead to a variety of birth defects that affect the structure of the nervous system, as well as more subtle changes … Continue reading →

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