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Potential Combination Therapy For Esophageal Cancer

Posted: Published on March 24th, 2012

Editor's Choice Academic Journal Main Category: Ear, Nose and Throat Also Included In: Cancer / Oncology Article Date: 23 Mar 2012 - 8:00 PDT email to a friend printer friendly opinions Current Article Ratings: In the March 20 issue of the journal Cancer Cell, researchers at The University of Texas MD Anderson Cancer Center reveal that the mTOR molecular pathway stimulates the activity of the Gli1 protein in the development and progression of esophageal cancer. Senior author of the study, Mien-Chie Hung, Ph.D., vice president for basic research, professor and chair of MD Anderson's Department of Molecular and Cellular Oncology, explained: Crosstalk between these two pathways is a challenge, but our experiments showed a combination of the mTOR inhibitor RAD-001 (Afinitor) and the Hedgehog inhibitor GDC-0449 (Erivedge) steeply reduced the tumor burden in a mouse model of esophageal adenocarcinoma." The U.S. Food and Drug Administration (FDA) has approved both drugs for use in other types of cancer. After examining 107 tissue samples of human esophageal cancer, the researchers found that 87 (81.3%) had a marker of Gli1 activated by Hedgehog and 80 (74.8%) had a marker of mTOR promotion of Gli1. According to the researchers less than 20% of individuals … Continue reading →

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In the Kirov region from 1 April will limit increases for vital and essential medicines

Posted: Published on March 24th, 2012

In the Kirov region from 1 April will limit wholesale and retail surcharges on the vital and essential medicines. As a reporter BakuToday, as stated by the Deputy Chairman of the Governments Dmitriy Matveev. According to him, the Government is constantly monitoring the issue of availability of medicines in the region. One means for doing so is to regulate the pricing on the vital and essential medicines (NVLP), included in the list. The Department of health in conjunction with the regional service on tariffs (PCT) conducts regular analysis of organizations engaged in wholesale and retail realization of medical products. Based on the analysis for the first quarter of 2012, decided to cut from April 1 limits of wholesale and retail size limits to actual vacations allowance prices manufacturers of medicines included in the list of NVLP. The PCT issued March 16. As pointed out by matveev, limits of wholesale and retail rates are set individually, depending on the cost: the more expensive drug product, the lower the amount of the allowances. Provides lower limits for drugs in three price groups with sales prices: up to 50 rubles inclusive-the ultimate wholesale margin drop from 20 to 19%, retail-with 40 to 35%; … Continue reading →

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FDA Mulls Expanding Patients' Access to Certain Drugs

Posted: Published on March 24th, 2012

By Amanda Gardner HealthDay Reporter THURSDAY, March 22 (HealthDay News) -- Americans troubled by a range of ailments might someday more easily obtain medications that are now only available by prescription. On Thursday and Friday, experts at the U.S. Food and Drug Administration (FDA) are holding hearings on whether to expand the availability of certain prescription drugs by giving them "conditional" over-the-counter, or OTC, status. The details of the new plan are sketchy, but certain drugs used to treat such conditions as high blood pressure, high cholesterol, diabetes, asthma and migraine may no longer require a prescription. Dispensing of these drugs would vary on a case-by-case basis and would include "conditions of safe use," possibly to be determined by the consumer with the help of a pharmacist. "There are a lot of unanswered questions right now but we're advocating that the pharmacist would be involved with the patient as they . . . determine if the product is right for them," explained pharmacist Ronna Hauser, vice president of policy and regulatory affairs at the National Community Pharmacists Association. "The information would be relayed back to a physician if necessary." According to Brian Gallagher, senior vice president of government affairs at … Continue reading →

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How much did drugs contribute to Whitney Houston's death?

Posted: Published on March 24th, 2012

Coroners rule that the "I Will Always Love You" singer used cocaine immediately before she died prompting further questions Just over one month after R&B supernova Whitney Houston was found dead in the bathtub of a Beverly Hilton hotel room, the Los Angeles County Coroner's Office is offering an official cause of death: Drowning due to heart disease and cocaine use. The singer's history of drug abuse is well-known, but how big of a role did drugs play in her death? Here, a brief guide: What did we already know about Houston's death? The "I Will Always Love You" singer was discovered in the bathtub, "underwater and apparently unconscious." Paramedics rushed to the scene and performed CPR for 20 minutes, but were unable to revive her. Small quantities of prescription drugs were found in Houston's suite, and the singer's most recent room service order included a Heineken and a glass of champagne. In the days before her death, Houston was spotted at the hotel "acting strangely, skipping around a ballroom, and doing handstands near the hotel pool," leading to speculation that she had been using drugs. SEE ALSO: Are boybands making a comeback? And now the coroner has an official … Continue reading →

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Drugs mule who died in Venezuela was on the run from gardaí

Posted: Published on March 24th, 2012

Drugs mule who died in Venezuela was on the run from garda By Paddy Clancy Saturday, March 24, 2012 The Irish drugs mule who died in Venezuela was on the run from garda and the courts here. Martin "Butch" Beirne disappeared from Sligo 18 months ago. He failed to appear at Sligo Circuit Court on a charge of possessing 2,000 of cannabis for sale and supply and a warrant was issued for his arrest. Beirne, 28, died on Wednesday in hospital when he was found collapsed in a hotel room in the Venezuela capital, Caracas. Two men travelling with him, in their 20s and from Galway, were due in court in Caracas yesterday on drug-trafficking charges. Beirne is believed to have ingested condom-wrapped bags of cocaine when one burst inside his body. His family in Boyle, Co Roscommon, have been informed of his death. Beirne was in Sligo town for eight years before he went on the run. Visit link: Drugs mule who died in Venezuela was on the run from gardaí … Continue reading →

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Shop ‘n Save Pharmacy Joins Diabetes Prevention and Control Alliance to Offer Approach to Help Control Diabetes

Posted: Published on March 24th, 2012

MINNETONKA, Minn.--(BUSINESS WIRE)-- Shop n Save Pharmacy, a division of SUPERVALU (NYSE: SVU - News), is joining UnitedHealth Groups Diabetes Prevention and Control Alliance (DPCA), giving Shop n Save Pharmacy customers access to the Alliances innovative, community-based Diabetes Control Program, based on curriculum that has been clinically proven to help control type 2 diabetes. Shop n Save Pharmacy is now offering the Diabetes Control Program at 26 locations in the St. Louis metro area. Shop n Save Pharmacy will provide patient education and support from trained pharmacists by appointment to help people with diabetes better control their condition and reduce the risk of developing complications such as cardiovascular, kidney and eye disease. In addition, pharmacists in these select Shop n Save Pharmacy locations will conduct blood glucose, cholesterol and blood pressure testing services for program participants and provide them with on-the-spot results, enabling patients to get immediate feedback on their status or progress in managing their diabetes. SUPERVALU is proud to partner with the Diabetes Prevention and Control Alliance to help make an impact on the nations diabetes epidemic through equipping andempowering patients to improve their health. Shop n Save pharmacists are well-positioned to improve our patients health due to … Continue reading →

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Daxor Announces That Shertech Pharmacy Acquires BVA-100 Blood Volume Analyzer

Posted: Published on March 24th, 2012

NEW YORK, NY--(Marketwire -03/23/12)- Daxor Corporation (AMEX: DXR - News), a medical instrumentation and biotechnology company, today announced the receipt of a signed trial agreement from Shertech Pharmacy in Charlotte, North Carolina. This agreement will provide Shertech with a Daxor BVA-100 Blood Volume Analyzer, an instrument which enables semi-automated measurement of a patient's total blood volume, red blood cell volume and plasma volume. Blood volume abnormalities are observed in a variety of cardiac conditions and have been associated with poor prognosis. Published studies using the BVA-100 have shown that blood volume measurement is important in treating heart failure, critical care patients in intensive care units, and in diagnosing the true status of complex anemias and syncope (fainting). Shertech Pharmacy is an independently owned specialty radiopharmacy with facilities in North and South Carolina and was founded in 1991. Shertech provides radio nuclear medical services to over 60 hospitals (the smallest being a 60-bed facility and the largest being an 890-bed facility) in the North and South Carolina areas. The Daxor BVA-100 will be housed at the Greenville Memorial Hospital in Greenville, SC. The medical community and retail public in the region rely on the friendly, well-trained staff to provide the highest … Continue reading →

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UPDATE: Daxor Announces That Shertech Pharmacy Acquires 2nd BVA-100 Blood Volume Analyzer

Posted: Published on March 24th, 2012

NEW YORK, NY--(Marketwire -03/23/12)- Daxor Corporation (AMEX: DXR - News), a medical instrumentation and biotechnology company, today announced the receipt of a signed trial agreement from Shertech Pharmacy in Charlotte, North Carolina. This agreement will provide Shertech Charlotte with a Daxor BVA-100 Blood Volume Analyzer. In February of 2012 Daxor placed a BVA-100 Blood Volume Analyzer at Shertech Pharmacy in Easley, South Carolina. Shertech Pharmacy has been providing radiopharmaceuticals, PET radiopharmaceutical products and services to the Carolinas since 2006. This combination of nuclear products is designed to more closely fit the growing demand of Nuclear Medicine, Nuclear Cardiology and Nuclear Oncology imaging and therapy. The pharmacy professionals in Shertech facilities provide the expertise necessary to offer these pharmaceutical specialties to a very active and patient oriented community like the Charlotte area. The North Carolina pharmacies in Charlotte and Kernersville (near Winston Salem and Greensboro) and South Carolina locations in Greenville, Spartanburg and Duncan provide nuclear diagnostics products in unit doses for individual patients. Shertech also provides prescription services to more than 175,000 patients annually and logs more than a million miles per year to ensure their time sensitive products are delivered when the customer needs them. The full gamut of … Continue reading →

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Fair Showcases Defense Progress in Traumatic Brain Injuries

Posted: Published on March 23rd, 2012

09:35 GMT, March 23, 2012 WASHINGTON | The U.S. Defense Department exhibited its latest technology and practices in the diagnosis and treatment of traumatic brain injuries at the 11th annual Brain Injury Awareness Day Fair here Mar. 21. The event at the House of Representatives Rayburn Building, which was jam-packed with information seekers, was sponsored by the Congressional Brain Injury Task Force in support of Traumatic Brain Injury Month. The fair featured nearly 60 federal agency and private-sector exhibitors, including the military services. Defense agencies at the fair included the Defense Centers of Excellence for Psychological Health and Traumatic Brain Injury, and its components, the National Intrepid Center of Excellence and the Defense and Veterans Brain Injury Center. Public awareness of traumatic brain injury overall has dramatically increased, said Joshua Stueve, the Intrepid Centers public affairs officer, who hosted his organizations exhibit. The big turnout from congressional and military staffers and the public was evidence of that awareness, he added. Numerous DOD products proved popular with visitors. One such item was the Deployment Mental Health Assessments Pocket Guide, a compact, yet comprehensive, booklet that outlines how to assess service members for TBI, post-traumatic stress disorder, depression, suicidal tendencies and other … Continue reading →

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Bioheart Labs and Stemlogix Veterinary Products Featured in Media

Posted: Published on March 23rd, 2012

SUNRISE, Fla., March 22, 2012 (GLOBE NEWSWIRE) -- Bioheart, Inc. (OTCBB:BHRT.OB - News), a company focused on developing stem cell therapies for heart disease, previously announced that they entered into an agreement with Stemlogix, LLC, a veterinary regenerative medicine company, to provide additional cellular products and services to the veterinary market. Under this agreement, the companies are offering stem cell banking for veterinary patients (pets). WPLG, channel 10 featured this exciting technology in a news segment which aired in the South Florida area. A small sample of tissue can be obtained from the animals during a routine procedure such as a spay or neuter. The stem cells are isolated and cryopreserved for future use as needed. "We are excited to bring our expertise in stem cell therapy to the veterinary community," said Mike Tomas, Bioheart's President and CEO. "Stem cell therapies represent new opportunities for various types of patients and the ability to bank a pet's cells when they are young and healthy could be very valuable for future use." WPLG, Channel 10 in Miami/South Florida featured this new technology in a news segment which aired March 15, 2012. Please see the link below: http://www.local10.com/thats-life/health/Pet-stem-cells-frozen-banked-for-future-use/-/1717022/9285894/-/apcx9rz/-/index.html About Bioheart, Inc. Bioheart is … Continue reading →

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