The prescription drugs finasteride, used to treat an enlarged prostate and male pattern baldness, and dutasteride, also to help men with the prostate condition, may increase the risk of high-grade prostate cancer, Health Canada warns. The warning, issued Monday, comes following reviews of two international trials. However, it notes that high-grade prostate cancer, which grows and spreads more quickly than low-grade prostate cancer, is rare, and the increased risk of using the two drugs is still considered very small. As a result of the assessment of the trials, new safety warnings have been added to the Canadian drug labels for finasteride and dutasteride products. Updates to labels for the generic forms of the two drugs are also coming. Following are more details of the drugs: Finasteride is available under the brand names Proscar (5 mg finasteride) and Propecia (1 mg finasteride), and their generic equivalents. Dutasteride is available under the brand names Avodart and Jalyn (a combination drug product containing dutasteride and tamsulosin). Proscar, Avodart and Jalyn treat benign prostatic hyperplasia (BPH), or an enlarged prostate, a common condition in men over 40. Propecia is used to treat male pattern hair loss. Health Canada says its review of the Prostate … Continue reading
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