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Afghan Shooting Highlights Military’s God-Awful Track Record on Brain Injuries

Posted: Published on March 15th, 2012

Soldiers at Joint Base Lewis-McChord, undergoing part of a grueling two-week training program for field medical staff. Photo: U.S. Army What spurred one American soldier to allegedly massacre 16 Afghan civilians earlier this week? Thats a complicated question, and one that could take military investigators months or years to figure out. What is known, among sparse details, is that this soldier suffered a traumatic brain injury (TBI). That factor will no doubt play a role in the militarys investigation, and it offers yet another reminder of the militarys awful track record in diagnosing and treating that ailment, widely known as one of the signature wounds of the wars in Iraq and Afghanistan. In my years reporting on TBIs among soldiers and vets, its become increasingly apparent that problems in TBI management start even before a soldier deploys, and persist often with devastating results long after he or she comes home. We got hit a lot of times in Iraq, [so] I definitely got rattled around,Staff Sgt. Victor Medina, a soldier afflicted with TBI, told me in 2010. It wasnt until the fourth time we got hit, and I blacked out, that anyone took me to get looked at. Medina later … Continue reading

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Managing multiple sclerosis – Video

Posted: Published on March 15th, 2012

13-03-2012 11:07 Multiple sclerosis can be difficult to diagnose. Dr. Steven Bromley discussesdiagnosis and management of the disease, and the continuum of care Virtua Neurosciences offers patients -- enabling them to live healthy, happy lives. See the original post here: Managing multiple sclerosis - Video … Continue reading

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'Liberation therapy' MS trials open to Yukoners

Posted: Published on March 15th, 2012

Yukoners with multiple sclerosis have a chance to participate in clinical trials for a controversial treatment. There are up to six secured spots for Yukoners for the so-called 'liberation treatment' clinical trials in Albany, New York. Initially, the territory was to take part in clinical trials in Saskatchewan. Jenny Roberts, the president of the Yukon Multiple Sclerosis Association, says its members urged the Yukon Government to get in on the treatment at the beginning. "We usually get ignored because of our geographical location, so that was our pressure that we did put on them, that, 'don't exclude us and if we have an opportunity we have to explore it'. And the YTG (Yukon Territorial Government), Minister of Health and the deputy minister has listened and worked with us very closely to get to this point," she said. Roberts says the association's members are very excited about the chance to participate in the trials. Applicants must be between 18 and 60 years old, have a valid passport and they cannot have had past liberation treatments. The therapy is also known as Zamboni therapy after it was pioneered by Italian doctor Paolo Zamboni. Zambonis procedure uses angioplasty to widen neck veins. His … Continue reading

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European Multiple Sclerosis Market in Dire Need of Increased Disease Awareness and Treatment Options, Cautions Frost …

Posted: Published on March 15th, 2012

LONDON, March 14, 2012 /PRNewswire/ -- Limited awareness about the disease and its overall occurrence and progression among end-users is hampering the European multiple sclerosis (MS) market. This is being exacerbated by the limited availability of accurate diagnostic tools. There is, therefore, an immediate need for innovative and enhanced therapeutic and diagnostic tools that support improved diagnosis and expand the range of treatment options. New analysis from Frost & Sullivan (http://www.pharma.frost.com), Analysis of the European Multiple Sclerosis Market, finds that the market earned revenues of approximately $3.2 billion in 2010 and estimates this to reach approximately $5.38 billion in 2017, growing at a compound annual growth rate (CAGR) of 7.2 per cent from 2010-2017. The segments covered include: immunosuppressants, immunomodulators and corticosteroids. "The rising number of people suffering from MS is resulting in higher demand for therapeutics," notes Frost & Sullivan Research Analyst Deepika Pramod Chopda. "This, coupled with strong pipeline development, is pushing robust growth in the overall market." MS is characterised as a chronic disease, commonly diagnosed in patients between 20-50 years of age. It affects more than 2.5 million people across the world, with Europe accounting for nearly 550,000 cases. Significant research is currently underway to efficiently … Continue reading

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MS awareness week continues

Posted: Published on March 15th, 2012

The National Multiple Sclerosis Society, North Florida Chapter is painting the town orange the official color of MS awareness during Multiple Sclerosis Awareness Week which concludes Sunday. MS Awareness Week will kicked off Monday. with an awareness and fundraising event at Bogey Grille in Ponte Vedra Beach, where the public was invited to a free screening of the movie The Ride starring The Amazing Race host Phil Keoghan cycling across the country to raise awareness for the National MS Society and Bike MS. A portion of the proceeds raised from the evenings food and beverage sales will benefit the National MS Society. Also on Monday the Alhambra Theatre spread MS awareness by lighting the garden and front yard of the theatre in orange through Sunday. The door man will also don orange attire and information about MS, the Society and Walk MS one of the Societys main annual fundraisers will be displayed. In addition, more than 50 people in the North Florida are registered with the Chapter as MS Ambassadors who will receive prizes and materials to help raise awareness in the 36 counties that the North Florida Chapter serves. They will spread awareness through email, social media and by … Continue reading

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Yukoners with MS eye clinical trials in New York

Posted: Published on March 15th, 2012

Yukoners suffering from multiple sclerosis (MS) will have the chance to undergo clinical trials of the liberation treatment. About six Yukon residents will be chosen for the controversial treatment in Albany, N.Y., after passing a series of screenings. The procedure uses angioplasty to widen blood vessels, and is reported to improve everything from eyesight to fatigue. Its not yet legal in Canada, and many Canadians have flown to places like Costa Rica and India to undergo the procedure. Were all patting ourselves on the back for all the hard work weve done to get to this point, Jenny Roberts, a Whitehorse resident with MS and the president of the territorys MS association, told the Star today. Roberts said the association invited then-Health and Social Services minister Glen Hart and deputy minister Stuart Whitley to a monthly meeting a year ago. They wanted to learn whether the government would send Yukoners to Saskatchewan to participate in the provinces trials. The government agreed to partnering with the Saskatchewan Health Research Foundation by sending about a dozen Yukoners down south for trials. But they never happened. Once the trials fell through, we were concerned what would happen, Roberts said. These new trials involve … Continue reading

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QF signs research deal with HMC

Posted: Published on March 15th, 2012

Qatar Foundation for Education, Science and Community Development (QF) has signed a research collaboration agreement with Hamad Medical Corporation (HMC), driven by a shared desire for further advancement in stem cell research, with the ultimate goal of preventing cancer from evolving to a life- threatening stage. The world loses millions of people to cancer, which is why Qatar Foundation strives to combat this disease, Faisal Mohammed al-Suwaidi, president, research and development, QF, said, adding: The use of stem cells in researching new treatments has begun to prove its effectiveness, so we are undertaking more studies in this field. This will undoubtedly contribute to building a better future for mankind. The agreement was signed by al-Suwaidi and Edward Hillhouse, HMCs senior policy adviser for academic health systems and acting medical director. Abdelali Haoudi, QF vice-president of research and deputy director of Qatar Biomedical Research Institute (QBRI), commented: QF, through the QBRI, has established a new research collaboration agreement with HMC, which has the potential to deliver major advances in the field of stem cell therapy applied to cancer. Our joint efforts will not only work to discover treatments designed to destroy cancer cells, but revolutionise the scientific approach to fighting disease … Continue reading

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Leukemia gene mutations linked to survival odds

Posted: Published on March 15th, 2012

(Reuters) - Advances in genetic profiling are paving the way for more precise, and effective, treatment of the aggressive bone marrow cancer known as acute mylogenous leukemia, or AML, according to new research. Two studies, published in the latest edition of the New England Journal of Medicine, show that genetic testing can guide doctors in how best to use current therapies as well as identify new drug targets. "As lots of studies identify new alterations in genes in leukemia and other cancers, we need to begin to understand how these alterations in DNA can predict outcomes and determine differences in treatment," said Dr. Ross Levine of Memorial Sloan-Kettering Cancer Center in New York, the lead author of one of the studies. Such personalized therapy is considered the new frontier for medical practice, and hopes for its success underpin a $5.7 billion hostile bid by drugmaker Roche Holding for gene sequencing company Illumina. The second study, from Washington University in St. Louis, found that 85 percent of bone marrow cells in patients with myelodysplastic syndrome, a blood-related disorder that can precede AML, were linked to mutations in progressive cancer. The Sloan-Kettering study analyzed bone marrow samples from 502 AML patients for … Continue reading

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Scientists Map Genetic Evolution of Leukemia

Posted: Published on March 15th, 2012

Newswise The diagnosis of myelodysplastic syndrome, a blood cancer, often causes confusion. While some patients can be treated with repeated blood transfusions, others require chemotherapy, leaving some uncertainty about whether the syndromes actually are cancer. Now, using the latest DNA sequencing technology, scientists at the Washington University School of Medicine in St. Louis have shown that the blood disease is an early form of cancer with characteristics that are very similar to the fatal leukemia to which it often progresses. And by mapping the genetic evolution of cancer cells in seven patients with myelodysplastic syndromes who later died of leukemia, they have found clues to suggest that targeted cancer drugs should be aimed at mutations that develop early in the disease. The research, by a large team of Washington University researchers at the Siteman Cancer Center, appears online March 14 in the New England Journal of Medicine. The scientists sequenced all the DNA the genome of tumor cells from the patients over time. While some cancer cells in each patient acquired new mutations as they evolved, they always retained the original cluster of mutations that made the cells cancerous in the first place. This discovery, which must be confirmed in … Continue reading

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Genetic Profiling Can Help Doctors More Accurately Predict Prognosis and Guide Treatment Decisions for Leukemia Patients

Posted: Published on March 15th, 2012

Newswise NEW YORK, MARCH 14, 2012 Researchers have identified a set of genetic abnormalities in patients with acute myelogenous leukemia (AML) that doctors can use to more accurately predict patients prognoses and select treatments that are most likely to benefit them. The study, led by investigators at Memorial Sloan-Kettering Cancer Center, will be published in the March 22 issue of the New England Journal of Medicine. Our study shows that genetic profiling makes it possible to more precisely categorize which patients are most likely to have their leukemia return after treatment, says the studys lead author Ross Levine, MD, a member of Memorial Sloan-Ketterings Human Oncology Pathogenesis Program. We also want to use existing therapies more intelligently. It helps a great deal to know which subset of patients will actually benefit from intensive therapies, such as a higher dose of chemotherapy or a bone marrow transplant, adds Dr. Levine, who is also a medical oncologist on the Leukemia Service at Memorial Sloan-Kettering. At present, clinicians rely on only a handful of known genetic biomarkers (early markers of disease) to predict outcome in leukemia patients, and these biomarkers provide useful information for only a subset of patients. For most people diagnosed … Continue reading

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