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Statewide Initiative Aims to Curb Epidemic of Painkiller Overuse

Posted: Published on March 14th, 2012

Primary Care Providers, Health Departments, Behavioral Health Providers and Hospitals Join Forces in Community-based Chronic Pain Initiative Raleigh, North Carolina (PRWEB) March 14, 2012 The sheer volume of the problem is staggering: According to the CDC, enough prescription painkillers were prescribed in 2010 to medicate every American adult around-the-clock for an entire month. A recent report by the Institute of Medicine suggests that the U.S may be spending as much as $635 billion annually to treat chronic pain and that long-term pain impacts more patients in the U.S. than heart disease, cancer and diabetes combined. In an unfortunate corollary, this flood of narcotics is driving an epidemic of prescription drug overdoses. Nationally, such deaths rose five-fold between 1990 and 2007. This loss of life has had a devastating impact on families all across our state. And even when problems arent fatal, the inappropriate use of pain medications significantly impacts the entire community. To address this public health challenge, a broad coalition of stakeholders has launched the Chronic Pain Initiative. This expansive partnership includes Community Care of North Carolina (CCNC), Project Lazarus, the North Carolina Hospital Association (NCHA), the North Carolina College of Emergency Physicians, local hospitals and emergency departments, local … Continue reading →

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Drugs found in student’s car

Posted: Published on March 14th, 2012

By Jeremiah Tucker, Sauk Prairie Eagle | Posted: Wednesday, March 14, 2012 8:54 am | A 17-year-old Sauk Prairie High School student was cited for possession of drug paraphernalia last week after police searched her car parked near school grounds and found materials they said they think were used to intravenously inject amphetamine The car was parked in the 100 block of Ninth Street and searched as part of a schoolwide K-9 search by the Sauk Prairie Police Department on Thursday. After the K-9 dog indicated it smelled drug residue, the police searched the car by hand and uncovered cooking tins, a rubber band, two needles and cotton filters, according to a police report. Lt. Travis Hilliard said the materials were consistent with heroin use, but one needle and drug residue found in the car both tested positive for amphetamine, which can be found in prescription drugs. Hilliard said he thinks the pills were being crushed, heated and injected in a manner similar to heroin. Hilliard said the student was cited and released to her parents. Our biggest concern is that weve had reports that some kids are using heroin, Hilliard said. When asked if the drug is prevalent among … Continue reading →

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Federal Authorities Investigating OKC Pharmacy – Video

Posted: Published on March 14th, 2012

13-03-2012 09:12 The Oklahoma County district attorney is getting involved with an investigation into Reliable Pharmacy. KOCO Eyewitness News 5's Michael Seiden has the story. See the original post here: Federal Authorities Investigating OKC Pharmacy - Video … Continue reading →

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Perry's stem-cell firm draws FDA scrutiny

Posted: Published on March 14th, 2012

The U.S. Food and Drug Administration has received a complaint alleging the Houston company involved in Gov. Rick Perry's unregulated adult stem-cell operation is a potential danger to patients and not in compliance with federal law. In an eight-page letter sent last month, University of Minnesota bioethicist Leigh Turner called on the FDA to investigate Celltex Therapeutics Corp., which banks people's stem cells for future reinjection in the event of disease or injury. Perry was the company's first customer last year. "It appears their business plan involves injecting or infusing on a for-profit, commercial basis non-FDA-approved adult stem cells into paying customers," Turner wrote in the Feb. 21 letter. "This plan conflicts with FDA regulations governing human stem cells." An FDA spokeswoman declined comment, but Turner said an agency official told him the matter has been assigned to an investigator and is being taken seriously. Celltex co-founder David Eller said Tuesday night he is confident the company will "meet all FDA specifications." He emphasized that Celltex doesn't administer stem cells, but stores and processes them at the behest of doctors who later reinject them into patients. Dr. Stanley Jones, a Houston orthopedic surgeon, injected Perry's stem cells during his back … Continue reading →

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Gut Cells Turned To Insulin Factories – New Type l Diabetes Treatment

Posted: Published on March 14th, 2012

Editor's Choice Academic Journal Main Category: Diabetes Article Date: 13 Mar 2012 - 12:00 PDT email to a friend printer friendly opinions Current Article Ratings: The study was carried out by Chutima Talchai, Ph.D, a New York Stem Cell Foundation-Druckenmiller Fellow, and Domenico Accili, M.D., professor of medicine at Columbia University Medical Center. Type 1 diabetes is an autoimmune disease that kills cells in the pancreas which produce insulin, resulting in high levels of glucose in the blood. As the pancreas is unable to replace these cells, individuals suffering with the disease must inject insulin into themselves in order to manage their blood sugar. Patients must also monitor their sugar levels numerous times a day, as blood glucose that is too low or too high can be fatal. For scientists researching type 1 diabetes, one of the leading goals is to replace lost insulin-producing cells with new cells that release insulin into the bloodstream as needed. Even though researchers are able to generate these cells in the laboratory from embryonic stem cells, they are not suitable for transplant in patients as they do not release insulin appropriately in response to sugar levels, potentially resulting in a deadly condition called hypoglycemia. … Continue reading →

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StemCells, Inc. Reports Fourth Quarter and Year End 2011 Financial Results and Provides Business Update

Posted: Published on March 14th, 2012

NEWARK, Calif., March 13, 2012 (GLOBE NEWSWIRE) -- StemCells, Inc. (Nasdaq:STEM - News), a leading stem cell company developing and commercializing novel cell-based therapeutics and tools for use in stem cell-based research and drug discovery, today reported financial results for the fourth quarter and year ended December 31, 2011 and provided a business update. "The StemCells team made significant progress in 2011 with regard to two critical goals for the Company, namely accelerating and broadening our HuCNS-SC neural stem cell clinical trial agenda for diseases of, and injuries to, the central nervous system, while at the same time reducing our operating cash burn. We are now uniquely positioned as the only stem cell company pursuing clinical trials for disorders of all three organs of the CNS, the brain, spinal cord and eye," said Martin McGlynn, President and CEO of StemCells, Inc. "We have strong preclinical data underlying all our clinical trials, much of which has already been published in peer-reviewed journals, but we realize that the true test of our proprietary cell-based technology will be in the clinic. In this regard, I am pleased to confirm StemCells remains on track to report safety and efficacy data from our recently completed … Continue reading →

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Completed Pancreatic Cancer Phase 1-2 Trial Concluded the Encapsulated Cells Produced Chemotherapy That May Treat …

Posted: Published on March 14th, 2012

SILVER SPRING, Md.--(BUSINESS WIRE)-- Nuvilex, Inc. (OTCQB:NVLX), an emerging biotechnology provider of cell and gene therapy solutions, discussed today the proprietary Cell-in-a-Box technology, being acquired from SG Austria, that was used for the pancreatic cancer clinical trial and may have an effect on downstream micro metastatic disease. The proprietary Cell-in-a-Box technology capsules, when used in combination with cytochrome P450 expressing cells, can be placed at the tumor site so that the cells inside the capsule can convert the drug ifosfamide. When the patient is subsequently injected with the chemotherapeutic drug ifosfamide, the encapsulated cells transform this prodrug into its active form, which kills the pancreatic cancer cells. It is extremely difficult to diagnose pancreatic cancer early on. Approximately 26% of people diagnosed have pancreatic cancer that spreads into the regions beside the tumor and 52% of patients have metastatic disease spread to regional lymph nodes and the liver. From trial and use data, for all pancreatic cancer stages combined there is only a 26% survival rate at 1 year, whereas using Cell-in-a-Box technology in the phase 1/2 clinical trial the 1-year survival rate was 36%, double that of the standard Gemzar therapy 1-year results of 18%. The advantage of this … Continue reading →

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A Drug Class Back From the Dead?

Posted: Published on March 14th, 2012

By Brian Orelli | More Articles March 13, 2012 | It looks like the anti-nerve growth factors might be able to re-emerge from the Food and Drug Administration clinical-hold graveyard. An FDA advisory panel recommended yesterday that the drugs are worth pursuing further despite the fact that osteoarthritis patients saw a higher rate of joint problems -- the very side effect that landed them on the FDA's naughty list. The big question: What the heck took so long? The FDA put the first clinical hold on Pfizer's (NYSE: PFE) tanezumab in June 2010 and halted the other anti-nerve growth factors being developed by Regeneron Pharmaceuticals (Nasdaq: REGN) , Sanofi (NYSE: SNY) , AstraZeneca (NYSE: AZN) , and Johnson & Johnson (NYSE: JNJ) by the end of that year. I'm all for keeping patients safe, but an earlier consult of the advisory panel sure would have been helpful for the companies and their investors -- it's not like the patent clock stops when drugs are put on clinical hold. The FDA doesn't have to follow the advice of the panel of outside experts, but with such an overwhelming majority saying the anti-NGF drugs are worth pursuing, I'd have a hard time … Continue reading →

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Selling baby wipes amid drug wars

Posted: Published on March 14th, 2012

By Caitlin Keating, reporter Claudio Gonzalez Laporte FORTUNE -- The United States has always had a complicated relationship with Mexico. We receive about 80% of the country's exports, we debate over how to handle Mexican immigrants who make up an increasingly important part of our workforce, and we travel to our southern neighbor's pristine beaches for winter vacations. It became more complicated last month, when the Department of State issued a travel warning about the security situation in Mexico. For decades, the country has been mired in crime, but the drug war has intensified there in the past year. Millions of U.S citizens safely visit Mexico each year, but the U.S. government is sounding alarms on the number of Americans murdered in Mexico recently: 120 U.S. visitors were killed there in 2011, up from 35 in 2007. So what is it like to do business there today? Claudio X. Gonzalez Laporte is the Chairman of Kimberly-Clark de Mexico, a subsidiary of Kimberly Clark (KMB) that's headquartered in Mexico City. The company sells everything from toiletries to hand towels and infant care. Gonzalez spoke with Fortune about the state of affairs in Mexico, the country's dependency on the United States, and … Continue reading →

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Selling baby wipes amid drug wars: Kimberly Clark on business in Mexico

Posted: Published on March 14th, 2012

By Caitlin Keating, reporter Claudio Gonzalez Laporte FORTUNE -- The United States has always had a complicated relationship with Mexico. We receive about 80% of the country's exports, we debate over how to handle Mexican immigrants who make up an increasingly important part of our workforce, and we travel to our southern neighbor's pristine beaches for winter vacations. It became more complicated last month, when the Department of State issued a travel warning about the security situation in Mexico. For decades, the country has been mired in crime, but the drug war has intensified there in the past year. Millions of U.S citizens safely visit Mexico each year, but the U.S. government is sounding alarms on the number of Americans murdered in Mexico recently: 120 U.S. visitors were killed there in 2011, up from 35 in 2007. So what is it like to do business there today? Claudio X. Gonzalez Laporte is the Chairman of Kimberly-Clark de Mexico, a subsidiary of Kimberly Clark (KMB) that's headquartered in Mexico City. The company sells everything from toiletries to hand towels and infant care. Gonzalez spoke with Fortune about the state of affairs in Mexico, the country's dependency on the United States, and … Continue reading →

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