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What Role Did Accused Soldier’s Brain Injury Play in Afghan Massacre? (UPDATED)

Posted: Published on March 14th, 2012

The link between traumatic brain injuries and a tendency to commit violent acts, like that which occurred in Afghanistan earlier this week, is still being unraveled by scientists. Photo: U.S. Air Force Its incredibly difficult to surmise what might have pushed one American sergeant to allegedly massacre 16 Afghan civilians.But new details about the still-unnamed staff sergeants background suggest that brain damage, wrought by a traumatic brain injury during an earlier deployment, might have been a contributing factor. It would be misleading, and downright reductionist, to suggest that TBI sufferers will commit murders. But scientists have linked brain trauma to some violent episodes. In an interview with ABC News on Monday, an unnamed source claimed that the sergeant suffered a TBI sometime in a past deployment, either by hitting his head on the hatch of a vehicle or in a car accident. A subsequent story from Reuters reported that the TBI occurred as recently as 2010. The alleged shooter is said to have later undergone TBI-specific treatment at Joint Base Lewis-McChord, before being cleared for duty and then redeployed. He also reportedly passed typical behavioral health assessments during his enlistment. The sergeant is hardly alone in suffering from a brain … Continue reading

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MS Poop Helping Keep Waterways Clean

Posted: Published on March 14th, 2012

MARTIN COUNTY,FL (WFLX) With miles of beautiful waterways, South Florida is a boating paradise. To make sure it stays the way, it's important to keep sewage from those boats out of the water. In Martin County, there's a free program that helps boaters do just that. So this story is about poop. More specifically, the "MS Poop." "I had to have something to get people kind of talking about it," laughs Darrell Schuler with the Martin County Utilities Department. "MS Poop" stands for the "Martin Ship Pump Out Operation Program." Operated by the Martin County Utilities Department, it is the "Poop's" job to keep sewage out of area waterways. It's a free service that first came into existence back in 2000. "People were trying to take care of the water but the problem back then was there just weren't enough places where people could pump out their sewage tanks conveniently," said Schuler. The county just got a state grant to keep the Poop in operation through next summer. So how does it work? The MS Poop shows up to where a vessel is docked or moored then connects a hose to the waste fitting on the vessel. About 25-35 boats … Continue reading

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Kessler Foundation MS study documents negative effect of warmer weather on cognition

Posted: Published on March 14th, 2012

Public release date: 13-Mar-2012 [ | E-mail | Share ] Contact: Carolann Murphy cmurphy@kesslerfoundation.org 973-324-8382 Kessler Foundation WEST ORANGE, N.J. -- Warm weather may hinder cognitive performance in people with multiple sclerosis (MS), according to results of a Kessler Foundation study e-published online ahead of print by Neurology. An accompanying editorial by Meier & Christodoulou, MS and heat: The smoke and the fire, details the study's unique aspects, ie, longitudinal followup in a cohort with apparently quiescent disease. Victoria M. Leavitt, Ph.D., research scientist at Kessler Foundation, is principal investigator for the study, which for the first time, shows a link between warm weather and cognition in people with MS. With more research, this information might help guide people with MS in making life decisions and assist their clinicians in choosing clinical treatment. Scientists may also want to consider the effect of warmer weather on cognition when designing and conducting clinical trials. Kessler Foundation co-investigators are James F. Sumowski, Ph.D., Research Scientist, Nancy Chiaravalloti, Ph.D., Director of Neuropsychology & Neuroscience Research, and John DeLuca, Ph.D., Vice President for Research. All also have faculty appointments at UMDNJ-New Jersey Medical School. Memory and processing speed were measured in 40 individuals with MS … Continue reading

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MS Drug Effective for Spinal Cord Injuries?

Posted: Published on March 14th, 2012

A drug found to slow some of the physical problems and reduce the number of flareups of multiple sclerosis (MS) could also show promise for treating spinal cord injuries, according to a new Japanese study. Researchers from the Jichi Medical University School of Medicine and the Universisty of Tokyo's Graduate School of Medicine found that FTY720, also known as Gilenya, helped mice with spinal cord injuries (SCIs) recover some motor function when they were given the drug immediately after the injuries. FTY720 acts in a number of ways, the study authors wrote. The drug, provided by its manufacturer, Novartis, for this study, suppresses the immune system, which reduces inflammation that occurs after injuries. Inflammatory effects, they explained, can worsen the damage done by SCIs. The drug also helped the mice's damaged tissue regenerate, among other effects. "The main biological activity responsible for these actions is believed to be immunological, but our data suggest that nonimmunological role(s) of FTY720 are also important in the treatment of SCI," they wrote. The drug still needs to be evaluated in larger animals before determining whether it is effective in treating SCIs, but still has promise, the authors added. Experts not involved with the study, … Continue reading

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3rd Grader With Brain Virus Gets Community Support

Posted: Published on March 14th, 2012

Greensboro, NC-- The staff and community surrounding Archer Elementary School are raising money to help the family of a very ill third-grade student. Two Archer Elementary School teachers detected something was wrong with their student, Melanie Mayo-Tornez, when she would shake uncontrollably during assignments and started walking funny. Teachers tell News 2 it seemed to have happened all of a sudden. Miss Lakisha Graham said, "It kind of brought to mind someone who has suffered a stroke. She washaving a hard time just being able to move, the tremors, just all those things I was observing with her that day." "Her right foot was kind of slapping the sidewalk which I had never noticed before and she didn't know I was watching and alarm bells went off", added ESL Teacher, Cindy Hilbinger. Theteachers brought their observations to the family. Melanie was later diagnosed with, "Acute Cerebellar Ataxia", essentially a cold virus settling around her brain. Mrs. Hilbinger said the mother in her kicked in when she saw the desperation in her student's face. She knew something was severely wrong with the usually vibrant, sweet student. "It's just not7-3 with June, July, and August off, that's just not true. We carry … Continue reading

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Stem Cell Project Wins Cloud Computing Competition

Posted: Published on March 14th, 2012

By Matthew Dublin Cycle Computing has named Victor Ruotti, a computational biologist at the Morgridge Institute for Research, as the 2011 CycleCloud BigScience Challenge. Finalists' proposals were selected based on their benefit to humanity, originality, creativity and suitability. Entrants submitted projects that focus Parkinsons disease, diabetes, organic photovoltaics, genomic diversity mapping. The finalists were judged by Jason Stowe, CEO, Cycle Computing, as well as Matt Wood, technology evangelist for Amazon Web Services, and Peter Shenkin, vice president at Schrdinger. Ruotti will be awarded $10,000 of time the equivalent of eight hours on a 30,000-core cluster on their cloud. In his submission for the contest, Ruotti proposed a knowledgebase indexing system for Human Embryonic Stem Cells and their derivatives, which usually requires hours of computational times. The high throughput computing power of CycleCloud will enable the classification of currently uncharacterized cell types, including hES cells and iPS cells from our laboratory, says Ruotti. The transcript profiles from each cell type will be analyzed and compared by aligning billions of sequencing reads in combinatorial pair wise steps. By doing so, we will create the first read level index to yield classified cellular derivatives along with methods to produce these cell types in … Continue reading

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A new approach to faster anticancer drug discovery

Posted: Published on March 14th, 2012

Public release date: 13-Mar-2012 [ | E-mail | Share ] Contact: Scott LaFee slafee@ucsd.edu 619-543-6163 University of California - San Diego Tracking the genetic pathway of a disease offers a powerful, new approach to drug discovery, according to scientists at the University of California, San Diego School of Medicine who used the approach to uncover a potential treatment for prostate cancer, using a drug currently marketed for congestive heart failure. Their findings are published in the current online issue of the Proceedings of the National Academy of Sciences. "The science of genomics the study of all of the genes in a person and how these genes interact with each other and the environment has revealed many fundamental aspects of biology, including the mechanisms of diseases like cancer. But it has not yet been truly exploited to find new medicines to treat those diseases," said Xiang-Dong Fu, PhD, professor of cellular and molecular medicine and senior author of the PNAS paper. Fu, with colleagues at UC San Diego and elsewhere, describe a unique screening strategy that compares genes associated with specific disease phenotypes (traits) with small molecules capable of intervening with disease-linked gene-expression events. The high-throughput process, capable of analyzing large … Continue reading

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Environmental groups call for tighter regulation of ‘extreme genetic engineering’

Posted: Published on March 14th, 2012

Genetically engineered microbes that might one day churn out biofuels, clean up toxic waste or generate new medicines need to be proved safe before they are released into the environment, a coalition of 111 environmental and social justice groups said Tuesday. Led by the environmental advocacy group Friends of the Earth, the coalition also called for stronger government regulations over extreme genetic engineering and a moratorium on the commercial use and release of lab-created organisms. Without proper safeguards, we risk letting synthetic organisms and their products out of the laboratory with unknown potential to disrupt ecosystems, threaten human health and undermine social, economic and cultural rights, the coalition said in a new report. The technology to manipulate the genes of bacteria, yeast and other organisms has existed since the 1970s, leading to pest-resistant crops, bacteria that produce human insulin and other breakthroughs. But in 2010, biologist J. Craig Venter announced that his institute had invented synthetic biology by transplanting the entire genome of one bacterium into a different species, which then reproduced. While not qualifying as an entirely new organism, the lab-built microbe did fuel concerns that this technology presented new and hard-to-quantify risks. The White House jumped in, with … Continue reading

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Genetic Disease Foundation (GDF) Welcomes Dr. Eric Schadt, Mount Sinai School of Medicine, to its Medical & Scientific …

Posted: Published on March 14th, 2012

GDF has expanded its Medical & Scientific Advisory Board to keep the organization at the forefront of genomic medicine. new york, NY (PRWEB) March 13, 2012 Dr. Schadt brings a bold new research approach, which is premised on studying multiple genes and biological processes through the use of advanced technology and computer models to develop a better understanding of disease causes and ultimately better diagnostics and treatment. We are extremely pleased and privileged to welcome a thought-leader like Dr. Schadt to our Advisory Board, where he will help guide the organizations efforts, said Elisa Ross, GDF President. Its important that GDF stays at the very forefront of genomic medicine so that we can optimize use of funds and provide the most valuable information to others. An expert in computational mathematics and sequencing technology, Dr. Schadts research at companies including Merck & Co. and Roche Biosciences has helped revolutionize the integration of genetic and molecular profiling data to construct predictive models of disease that have led to a number of discoveries relating to causes of common diseases. He currently maintains his position as Chief Scientific Officer (CSO) at Pacific Biosciences, a third generation DNA sequencing company, where hes worked since 2009 … Continue reading

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StemCells, Inc. Reports Fourth Quarter and Year End 2011 Financial Results and Provides Business Update

Posted: Published on March 14th, 2012

NEWARK, Calif., March 13, 2012 (GLOBE NEWSWIRE) -- StemCells, Inc. (Nasdaq:STEM - News), a leading stem cell company developing and commercializing novel cell-based therapeutics and tools for use in stem cell-based research and drug discovery, today reported financial results for the fourth quarter and year ended December 31, 2011 and provided a business update. "The StemCells team made significant progress in 2011 with regard to two critical goals for the Company, namely accelerating and broadening our HuCNS-SC neural stem cell clinical trial agenda for diseases of, and injuries to, the central nervous system, while at the same time reducing our operating cash burn. We are now uniquely positioned as the only stem cell company pursuing clinical trials for disorders of all three organs of the CNS, the brain, spinal cord and eye," said Martin McGlynn, President and CEO of StemCells, Inc. "We have strong preclinical data underlying all our clinical trials, much of which has already been published in peer-reviewed journals, but we realize that the true test of our proprietary cell-based technology will be in the clinic. In this regard, I am pleased to confirm StemCells remains on track to report safety and efficacy data from our recently completed … Continue reading

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