While it can often work wonders against invading cancer cells, chemotherapy can also bring on very undesirable side effects, such as hair loss, nausea and vomiting. But the recent discovery of the structure of a certain molecule could potentially lead to the development of new drugs that could target tumors while avoiding damage to healthy tissue, resulting in possibly fewer side effects. The molecule, known as a transporter, can carry specific anticancer and antiviral drugs directly into cells. The drugs can then prevent tumor cells from dividing and multiplying. "If you really know what this transporter looks like, you can potentially design a cancer drug to be recognized by this transporter and carried into the cells, and you can lower the dose of cancer drugs and decrease the side effects as a result," said Seok-Yong Lee, an assistant professor of biochemistry at Duke University School of Medicine and lead author of the research, published online in the journal Nature. Experts not involved with Lee's research say development of such drugs is still a very long way off, but focusing on the ability of a drug to get into cancer cells makes scientific sense. "If it could be manipulated to help … Continue reading
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