Lindsay Porter's kidneys weighed 16 pounds before her transplant. STORY HIGHLIGHTS (CNN) -- By the time Lindsay Porter had her kidneys removed two years ago, they were bulging -- covered in cysts -- and together weighed 16 pounds. Her abdominal area was so distended, "I looked nine months pregnant, and people regularly asked when I was due," Porter said. As she prepared for a transplant to address her polycystic kidney disease, Porter, 47, had mixed feelings -- relief to have found a donor, tinged with resignation. She was looking forward to both a new kidney, and a lifetime on immune system-suppressing drugs. "You get this brand new shiny kidney, and then they give you drugs that eventually destroy it," said Porter. But that scenario may eventually change, if results of a new pilot study are replicated in a larger group of patients. The study, published Wednesday in the journal Science Translational Medicine, describes eight kidney transplant patients, including Porter, who received a stem cell therapy that allowed donor and recipient immune cells to coexist in the same body. The effect, in a handful of those patients, was to trick the recipient's immune system into recognizing the donated kidney as its … Continue reading
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