A U.S. Food and Drug Administration Advisory Committee today recommended approval of the weight loss drug Qnexa, a treatment many hope will help millions of Americans who struggle with obesity . In voting 20 to 2 for approval, the committee said today that Qnexa's weight loss benefits for the chronically obese outweighed the risks of birth defects and cardiovascular problems that have been associated with the drug. An FDA advisory panel recommended against approval in 2010 over concerns about the drug's side effects, and the FDA rejected it shortly after that. Vivus, the drug's manufacturer, recently submitted additional research. The committee today recommended that the manufacturer take a number of steps to prevent the drug from causing birth defects like cleft palate, including a possible warning label targeted toward women of childbearing years. The FDA has considered numerous anti-obesity drugs in the past 20 years, but most have failed to meet the agency's standards for safety and effectiveness. But so far, data on Qnexa suggests that the drug is the most effective in helping patients shed up to 10 percent of their body weight. Those changes, along with diet and exercise modifications, could go a long way toward alleviating some of the health … Continue reading
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