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Autism Speaks provides sleep strategies and dental treatment tool kits

Posted: Published on February 21st, 2012

Public release date: 21-Feb-2012 [ | E-mail | Share ] Contact: Jane E. Rubinstein jrubinstein@rubenstein.com 212-843-8287 Autism Speaks NEW YORK, N.Y. (February 21, 2012) ? Autism Speaks, North America's leading autism science and advocacy organization, today released the Sleep Strategies for Children with Autism: A Parent's Guide and Treating Children with Autism Spectrum Disorders: A Tool Kit for Dental Professionals, both available for free download on Autism Speaks Tools You Can Use webpage. Many children with autism spectrum disorder (ASD) have difficulty falling asleep and/or staying asleep through the night, so sleep experts in Autism Speaks Autism Treatment Network (ATN) and the companion Autism Intervention Research Network on Physical Health (AIR-P) have addressed how to help improve sleep for children and teens affected by ASD. The Sleep Strategies Guide helps families select ideas that have the best potential to work well with their lifestyle. It recommends that families implement their sleep plan when they have the time and energy to see if it will work, trying one small change, and then slowly incorporating other changes. With consistent routines and persistent effort, families often see changes in their child's sleep patterns over several weeks. "If your child or teen with ASD … Continue reading

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Blood clot grabber could save stroke victims' lives

Posted: Published on February 21st, 2012

By Pat Hagan Last updated at 8:08 AM on 21st February 2012 A device that ‘traps’ blood clots so they can be safely removed from the brain could be a radical new treatment for stroke. The cage-like gadget ensnares the clot, allowing doctors to retrieve it so blood flow can quickly be restored. Strokes kill around 200 people every day in the UK, and it is estimated the NHS spends ?2.3?billion a year treating and looking after the 100,000 people annually struck down by the life-threatening condition. Strokes kill around 200 people every day in the UK Around 85 per cent of victims are affected by ischaemic strokes, where a clot travels to the brain and shuts off its blood supply. The rest suffer haemorrhagic strokes, where a blood vessel bursts in the brain, causing potentially fatal bleeding. Under current treatment guidelines, ischaemic stroke victims are treated with a clot-removing drug called tissue plasminogen activator. But this is only really effective within the first three hours after a stroke, after which a clot may be too hard and well-developed to break up with drugs.    However, the experimental new gadget, called the Solitaire Flow Restoration Device, could potentially be used … Continue reading

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Promising new compound for treating stroke

Posted: Published on February 21st, 2012

Public release date: 21-Feb-2012 [ | E-mail | Share ] Contact: Anders Bach anba@farma.ku.dk (45) 40-32-08-06 University of Copenhagen Researchers at the University of Copenhagen have designed, produced and patented a new chemical compound for the possible treatment of brain damage caused by stroke. The compound binds 1,000 times more effectively to the target protein in the brain than the potential drug currently being tested on stroke victims. The results of biological tests have just been published in the renowned journal PNAS. More than 140,000 people die each year from stroke in the United States. Stroke causes the brain to release large amounts of glutamate, an activating signal compound, all at once. This overactivates the receptors in the surrounding healthy tissue, causing the level of calcium in the cells to rise dramatically. This then kick-starts a toxic chain reaction causing cell death. Scientists believe that this process is the cause of the brain damage that occurs in the wake of a stroke. Therefore they are looking for compounds that can limit cell death: "Research on animal models shows that the new compound we have designed and produced reduces the dead area in the brain after a stroke by 40 per … Continue reading

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NHS doctors pilot app to help patients get best treatment

Posted: Published on February 21st, 2012

MEDICAL experts from the North East are piloting a new tool to ensure stroke patients get the best treatment. Having developed the FAST acronym – face, arms, speech and time – which has been seen on national TV adverts, the Newcastle University and NHS team are now trying out an app for use on smartphones or tablets. The iPad app, called DASH II, aims to help people who have had a stroke and their medical team work out which course of treatment is most suitable for them. The app is being trialled in Newcastle and North Tyneside hospitals to help weigh up the risks and benefits of different treatments for people who have had an ischaemic stroke, which is caused by a blood clot on the brain. Its potential benefits have caught the attention of the national NHS after the researchers were nominated by a public vote as one of the top 50 uses of technology. The app will be demonstrated to the Health Secretary Andrew Lansley at the Maps and Apps Showcase in London tomorrow. From the moment people suffer a stroke, medics only have a four and a half-hour window to treat them with clot-busting drugs. This means … Continue reading

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The app that could save life after a stroke

Posted: Published on February 21st, 2012

MEDICAL experts from the North East are piloting a new tool to ensure stroke patients get the best treatment. Having developed the FAST acronym – face, arms, speech and time – which has been seen on national TV adverts, the Newcastle University and NHS team are now trying out an app for use on smartphones or tablets. The iPad app, called DASH II, aims to help people who have had a stroke and their medical team work out which course of treatment is most suitable for them. The app is being trialled in Newcastle and North Tyneside hospitals to help weigh up the risks and benefits of different treatments for people who have had an ischaemic stroke, which is caused by a blood clot on the brain. Its potential benefits have caught the attention of the national NHS after the researchers were nominated by a public vote as one of the top 50 uses of technology. The app will be demonstrated to the Health Secretary Andrew Lansley at the Maps and Apps Showcase in London tomorrow. From the moment people suffer a stroke, medics only have a four and a half-hour window to treat them with clot-busting drugs. This means … Continue reading

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High Doses of Load Slows Bone Loss in Spinal Cord Injury

Posted: Published on February 21st, 2012

Newswise — Loss of bone density leads to brittle bones that fracture easily. It is a major complication of spinal cord injury (SCI), which affects about 250,000 Americans every year. A new clinical trial conducted by University of Iowa researchers shows that delivering high doses of "load," or stress, to bone through programmed electrical stimulation of the muscle significantly slows the loss of bone density in patients with SCI. The focus on quantifying the effective dose of load is one of the study's most important aspects, says Richard Shields, P.T., Ph.D., a professor and director of the UI Physical Therapy and Rehabilitation Science Graduate Programs. The study also is the first to carefully test the impact of different doses of load in humans with paralysis. Previous research had suggested that stressing or loading bone through muscle contractions could slow the loss of bone density, but results from clinical trials have been mixed. "Thirty years ago a clinical trial concluded that putting patients with SCI in an upright weight-bearing position with braces or standing frames did nothing to prevent loss of bone density," Shields says. "The novelty of our study is we have designed a method for individuals with paralysis to … Continue reading

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Parkinson's Disease – How Much Exercise Improves Symptoms?

Posted: Published on February 21st, 2012

Editor's Choice Main Category: Parkinson's Disease Article Date: 20 Feb 2012 - 9:00 PST email to a friend   printer friendly   opinions   Current Article Ratings: Patient / Public: 5 (5 votes) Healthcare Prof: For over two decades, Daniel Corcos has researched Parkinson's disease. During his studies he spent the majority of the past decade focusing on the effects of exercise. Corcos, a professor of kinesiology and nutrition at the University of Illinois at Chicago, explained: "It became obvious several years ago that exercise really was good for people with Parkinson's disease. Not only is it good for the heart, the brain, and muscles in the same way it is for healthy people, it also modifies signs and symptoms of Parkinson's disease." At present, Corcos is co-leading a study funded by a four-year, $3 million grant from the National Institute of Neurological Disorders. The aim of the study is to assess the benefits of aerobic exercise in controlling symptoms in individuals recently diagnosed with Parkinson's disease. At the annual meeting of the American Academy of Neurology in April, 2012, Corcos will present findings from the study. Results from the study show that 2 years of weight training can considerably … Continue reading

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Purdue researchers reveal role of protein mutation in Parkinson's disease

Posted: Published on February 21st, 2012

Public release date: 21-Feb-2012 [ | E-mail | Share ] Contact: Elizabeth K. Gardner ekgardner@purdue.edu 765-494-2081 Purdue University WEST LAFAYETTE, Ind. - Purdue University researchers revealed how a mutation in a protein shuts down a protective function needed to prevent the death of neurons in Parkinson's disease, possibly opening the door to new drug strategies to treat the disorder. Fred Regnier, the J.H. Law Distinguished Professor of Chemistry, and Jean-Christophe Rochet, an associate professor of medicinal chemistry and molecular pharmacology, led the team that discovered how the protein DJ-1, which plays a significant role in protecting neurons from damage, is shut down by a subtle mutation. A substitution in one link of the chain of amino acids that makes up the protein renders it unable to be activated to protect neurons from the build up of protein "aggregates," or "clumps," that lead to cell death in those with Parkinson's disease. "The saying that you are only as strong as your weakest link appears to hold true in the case of the chain of amino acids that make up a protein," Regnier said. "The magnitude of the effect of this subtle change is surprising. It can make the difference between having … Continue reading

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National Parkinson Foundation, Its Leading Medical Centers of Excellence and Chapters Nationwide Launch Aware in Care

Posted: Published on February 21st, 2012

To: HEALTH AND NATIONAL EDITORS New campaign to improve hospital care for over 1 million people with Parkinson's disease; Emerging data shows hospitalization puts Parkinson's patients at great risk MIAMI, Feb. 21, 2012 /PRNewswire-USNewswire/ -- The National Parkinson Foundation (NPF) announced the launch of the Aware in Care campaign today, the first-ever, nationwide initiative to address the growing problem of poor hospital care for over one million people with Parkinson's disease (PD). Aware in Care features a free kit for PD patients and caregivers to help make hospital stays safer. NPF, its Centers of Excellence at leading medical institutions, and local chapters urge patients and caregivers to know the steps to take to ensure that people with PD get the best possible care during hospital stays. "Our research scientists have unearthed important factors which can lower the risk of illness, serious complications and even death of hospitalized Parkinson's patients," said Michael S. Okun, MD, NPF's National Medical Director. "For my patients, and for the up to one million people suffering from Parkinson's in the U.S., Aware in Care will improve the type of attention and treatment they get in hospitals." Emerging data shows that 75% of hospitalized patients with PD … Continue reading

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Earnings Beat for Acorda

Posted: Published on February 21st, 2012

Acorda Therapeutics Inc.’s (NasdaqGS:ACOR - News) fourth quarter earnings (including share-based compensation charges) of 32 cents per share were way above the Zacks Consensus Estimate of 17 cents and the year-ago earnings of 9 cents per share. Fiscal year 2011 earnings (including share-based compensation charges) of 64 cents per share were also higher than the Zacks Consensus Estimate of 62 cents per share and the year-ago loss of 31 cents per share. The company reported earnings (excluding share-based compensation charges) of 45 cents and $1.13 per share for the fourth quarter of 2011 and fiscal year 2011, respectively. Quarterly revenues increased 8.7% to $72.6 million, beating the Zacks Consensus Estimate of $69 million. In fiscal year 2011, revenues increased a whopping 53.0% to $292.2 million. Revenues came in above the Zacks Consensus Estimate of $285 million. Quarter in Detail Product sales consisted mainly of Ampyra, which has patent protection till 2027. Ampyra sales came in at $57.2 million, reflecting a year-over-year increase of 9.4%. Acorda has a licensing agreement with Biogen Idec (NasdaqGS:BIIB - News) for the development and commercialization of Ampyra outside the US. Further, Acorda has a supply agreement with Elan Corporation (NYSE:ELN - News) for manufacturing Ampyra. … Continue reading

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