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Arrowhead Names HBV as Next RNAi Program While It Consolidates Operations

Posted: Published on February 16th, 2012

By Doug Macron Just months after its acquisition of Roche's RNA drug assets, Arrowhead Research has essentially completed the consolidation of its operations, including its RNAi drug subsidiary Calando Pharmaceuticals, into a single nanomedicine firm with a strong focus on RNAi therapeutics. The company also unveiled its newest RNAi program, a hepatitis B therapy combining standard 21-mer siRNA molecules with the dynamic polyconjugate delivery technology picked up from Roche, and expects to have a candidate in preclinical toxicology studies before the end of the year. Arrowhead also released its fiscal first-quarter financial results last week, posting higher losses amid increased operating costs associated with the research facility included in the Roche deal. Previously structured as a holding company for various subsidiaries, Arrowhead has long maintained an interest in RNAi through Calando, which in 2008 became the first company to bring a formulated siRNA-based drug into human testing with the cancer treatment CALAA-01. Recently, however, Arrowhead started to consolidate its various operating units into a single entity. In late 2011, it acquired Roche's RNA drug operations, including its 40-person Madison, Wisc.-based facility, providing a home for all of the company's research and development activities (GSN 10/27/2011). “Operationally, we are now running … Continue reading →

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World Stem Cells, LLC. Stem Cell Treatments In Cancun at Advanced Cellular Medicine Clinic

Posted: Published on February 16th, 2012

World Stem Cells, LLC Stem Cell Therapy at a state of the art clinic in beautiful Cancun. The clinic is staffed by top specialist in the field of stem cell implants and a new laboratory to support the stem cell treatments given. (PRWEB) February 16, 2012 World Stem Cells, LLC. contract laboratory Advanced Cellular Engineering Lab (Ingenieria Celular Advanzada S.A. de C.V.) a new adult stem cell laboratory being built in Cancun, Mexico to support Stem Cell research, stem cell clinical trials and stem cell treatments. This was accomplished by private funding in conjunction with World Stem Cells, LLC worldstemcells.com a US patient management company, Medicina Biocelular Avanzada , S.E. de C.V. a Mexican patient management company and Advanced Cellular Medicine Clinic of Cancun, a Stem Cell treatment Clinic owned and operated by Dr. Sylvia M. Abblitt a well known board certified hematologist and oncologist, in Cancun. Uniquely, Dr. Abblitt is one of a limited number of physicians licensed to perform autologous and allogeneic stem cell transplants. Dr. Abblitt has been utilizing stem cell therapies with successes for many years. She is the president and lab director of Advanced Cellular Engineering Lab (Ingenieria Celular Advanzada S.A. de C.V.). Her extensive … Continue reading →

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Cytomedix to Showcase Aldagen’s Promising Autologous Cell Therapy Technology at Two Regenerative Medicine Meetings

Posted: Published on February 16th, 2012

GAITHERSBURG, MD--(Marketwire -02/16/12)- Cytomedix, Inc. (OTC.BB: CMXI.OB - News) (the "Company"), a leading developer of biologically active regenerative therapies for wound care, inflammation and angiogenesis, today announced that Chief Operating Officer Edward L. Field will present a clinical overview of Aldagen's autologous cell therapy technology at two upcoming meetings: The Cell Society's 2nd Annual Clinical Meeting being held February 17-18 at the Coronado Marriott Resort in San Diego; and the 7th Annual New York Stem Cell Summit being held on February 21 at Bridgewaters New York in New York City. Mr. Field will present during the session, "Commercialization Opportunities with Adult Stem Cell Therapies," on Friday, February 17 from 8:00 a.m. to 10:00 a.m. Pacific time at the Cell Society meeting. Cell Society International is a non-profit organization dedicated to advancing the clinical application of adult stem cell therapies worldwide. Cell Society's 2nd Annual Clinical Meeting will continue in the tradition established at the 1st Annual Meeting and will offer a unique opportunity for multidisciplinary, international clinical collaboration designed to enhance understanding and thought-provoking insight into treatments and cures for disease and agonizing medical conditions. This year's clinical focus will center on therapies particularly relevant to cardiology, neurology, and orthopedic … Continue reading →

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Cytomedix to Showcase Aldagen's Promising Autologous Cell Therapy Technology at Two Regenerative Medicine Meetings

Posted: Published on February 16th, 2012

GAITHERSBURG, MD--(Marketwire -02/16/12)- Cytomedix, Inc. (OTC.BB: CMXI.OB - News) (the "Company"), a leading developer of biologically active regenerative therapies for wound care, inflammation and angiogenesis, today announced that Chief Operating Officer Edward L. Field will present a clinical overview of Aldagen's autologous cell therapy technology at two upcoming meetings: The Cell Society's 2nd Annual Clinical Meeting being held February 17-18 at the Coronado Marriott Resort in San Diego; and the 7th Annual New York Stem Cell Summit being held on February 21 at Bridgewaters New York in New York City. Mr. Field will present during the session, "Commercialization Opportunities with Adult Stem Cell Therapies," on Friday, February 17 from 8:00 a.m. to 10:00 a.m. Pacific time at the Cell Society meeting. Cell Society International is a non-profit organization dedicated to advancing the clinical application of adult stem cell therapies worldwide. Cell Society's 2nd Annual Clinical Meeting will continue in the tradition established at the 1st Annual Meeting and will offer a unique opportunity for multidisciplinary, international clinical collaboration designed to enhance understanding and thought-provoking insight into treatments and cures for disease and agonizing medical conditions. This year's clinical focus will center on therapies particularly relevant to cardiology, neurology, and orthopedic … Continue reading →

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Pathfinder to Present at New York Stem Cell Summit

Posted: Published on February 16th, 2012

CAMBRIDGE, Mass., Feb. 16, 2012 (GLOBE NEWSWIRE) -- Pathfinder Cell Therapy, Inc. ("Pathfinder," or "the Company") (OTCQB:PFND.PK - News), a biotechnology company focused on the treatment of diseases characterized by organ-specific cell damage, today announced that Richard L. Franklin, M.D., Ph.D., Founder, CEO and President of Pathfinder, will present at the 7th Annual New York Stem Cell Summit being held on Tuesday, February 21, 2012. Event: 7th Annual New York Stem Cell Summit Date: Tuesday, February 21, 2012 Place: Bridgewaters New York, 11 Fulton Street, New York, NY Time: 3:35 pm ET Dr. Franklin will be providing an overview of the Company's novel Pathfinder Cell therapy. The New York Stem Cell Summit brings together stem cell company executives, researchers, investors and physicians to explore investment opportunities in stem cell research and innovation. More information can be found at http://www.stemcellsummit.com. About Pathfinder Pathfinder is developing a novel cell-based therapy and has generated encouraging preclinical data in models of diabetes, renal disease, myocardial infarction, and critical limb ischemia, a severe form of peripheral vascular disease. Leveraging its internal discovery of Pathfinder Cells ("PCs") Pathfinder is pioneering a new field in regenerative medicine. PCs are a newly identified mammalian cell type present in … Continue reading →

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Boomer Addiction

Posted: Published on February 16th, 2012

advertisement People over the age of fifty have been entering drug treatment programs in greater numbers. In 1992, the 50-plus demographic accounted for 6.6 percent of all admissions. The most recent statistics available report that this group now accounts for 12.2 percent of all treatment admissions, according to data from the Substance Abuse and Mental Health Services Administration (SAMHSA). Peggy W. is one of those admissions. She is 58 years old, and in rehab for the first time. Peggy said she was “a real mess” when she entered Tarzana Treatment Center four months ago. She hit bottom last fall. “I was in a total black out from the sixth of October to the 17th. They did a blood alcohol on me it was .43. I should have been dead then,” Peggy said. To hear more of Peggy's story, click here. Peggy said she was a functioning addict for 44 years. Her abuse included drinking vodka in the morning and then working at a bar where she had access to even more alcohol. She also abused prescription pills and narcotics. Despite the toll this was taking on her health, she managed to work as a dispatcher, raise six children and go … Continue reading →

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Afghanistan can't be stable without drugs crackdown: U.N.

Posted: Published on February 16th, 2012

VIENNA (Reuters) - Afghanistan cannot be stable while its economy depends so heavily on the drugs trade, and its allies must step up the fight to combat the industry, U.N. Secretary General Ban Ki-Moon said on Thursday. Opening a major international conference on ways to combat narcotics production in Afghanistan and smuggling through neighboring states, Ban said the problem undermined efforts to help Afghanistan emerge as a normally functioning economy. "We cannot speak of sustainable development when opium production is the only viable economic activity in the country," he told delegates of the so-called Paris Pact Ministerial Conference, which first met in 2003. "We cannot expect stability when 15 percent of Afghanistan's gross domestic product comes from the drugs trade." The Vienna conference, with participants from more than 50 countries and international organizations including the foreign ministers of Russia and France, was due to adopt a new declaration at the end of a one-day session. With foreign combat forces, and much of their cash and air power, expected to be gone from the country by the end of 2014, the Afghan government will need more help fighting poppy cultivation, which rose over the last year, experts say. "Despite continued efforts … Continue reading →

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Drugs and delusions, American obsessions

Posted: Published on February 16th, 2012

Great Decisions last week dealt with Mexico. There was a good discussion led by Professors Heather Brady and Tim Gaster centering on drugs and drug cartels. My view — but not mine alone — is that these problems are not really Mexican problems, but reflect what is going on here. That is, American criminals carter to American vices, and Mexican gangsters want a part of the action. Mexico, Columbia, California, all are following a course we saw in our country during Prohibition, in that when the police are asked to enforce unpopular policies, criminals get rich, and the police and politicians become corrupted or ineffective. There are few who doubt that our society has a problem with drugs. People like them, whether it is coffee or alcohol or substances which only the foolish would use voluntarily. The world is full of fools. It is difficult to save a fool from folly, especially when the folly is both fun and a means of defying authority. Our experiment of 1919-1933, prohibiting the sale and consumption of alcohol, produced some good results, but more negative ones. So many citizens refused to obey the law, even mocked the government for its clumsy efforts to … Continue reading →

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UN chief notes losing fight against Afghan drugs

Posted: Published on February 16th, 2012

VIENNA (AP) — The U.N. secretary general on Thursday urged the international community to step up efforts to eradicate drugs in Afghanistan, noting that opium production there has grown by 61 percent in the past year and adding that "time is not on our side." In his opening statement to a meeting of top global representatives, Ban Ki-moon also warned that the problem extends beyond those who abuse drugs and is threatening Afghanistan itself. "Drug trafficking and transnational organized crime undermine the health of fragile states, (and) weaken the rule of law," he told delegates. "Above all, the Afghan government must prioritize the issue of narcotics." Afghanistan's minister for counter-narcotics, however, suggested that drugs can only be eradicated if security in his country is improved. Named for the agreement that created it nine years ago, the Paris Pact meeting is meant to review steps taken to reduce production and trafficking of opiates from Afghanistan. It will look at ways to block financial flows from the illicit drug trade, choke the flow of chemicals used to make heroin and strengthen local initiatives to help combat drug abuse by Afghans. But the meeting has no enforcing powers, and international attempts to reduce … Continue reading →

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Pharmacy heist, chase ends in arrest

Posted: Published on February 16th, 2012

GREENWOOD, Ind. (WISH) - A witness’s good description of a suspect’s getaway vehicle is being credited with helping Greenwood police make an arrest following the robbery of a Walgreens store Wednesday at 700 S. U.S. Highway 31. Police were called to the pharmacy at 10:21 p.m. Wednesday after employees reported a man robbed the store at gunpoint. A witness followed the armed suspect out of the store and was able to provide police with a description of the getaway vehicle. Within minutes, officers located a vehicle matching the same description and attempted to stop it. Police say the driver led them on a short pursuit through the Valle Vista neighborhood just south of Smith Valley Road. The suspect tried to lose the officers by driving through yards and eventually bailed out on foot. Police checked the vehicle’s registration and went to its registered owner’s home where they found a man matching the description of the robber. Police took the man, Jason Matthew Gray, into custody. He was booked into the Johnson County Jail. Continue reading here: Pharmacy heist, chase ends in arrest … Continue reading →

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