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Stem Cell Treatment Might Reverse Heart Attack Damage

Posted: Published on February 14th, 2012

MONDAY, Feb. 13 (HealthDay News) -- Stem cell therapy's promise for healing damaged tissues may have gotten a bit closer to reality. In a small, early study, heart damage was reversed in heart-attack patients treated with their own cardiac stem cells, researchers report. The cells, called cardiosphere-derived stem cells, regrew damaged heart muscle and reversed scarring one year later, the authors say. Up until now, heart specialists' best tool to help minimize damage following a heart attack has been to surgically clear blocked arteries. "In our treatment, we dissolved scar and replaced it with living heart muscle. Such 'therapeutic regeneration' has long been the holy grail of cell therapy, but had never been accomplished before; we now seem to have done it," said study author Dr. Eduardo Marban, director of the Cedars-Sinai Heart Institute in Los Angeles. However, outside experts cautioned that the findings are preliminary and the treatment is far from ready for widespread use among heart-attack survivors. The study, published online Feb. 14 in The Lancet, involved 25 middle-aged patients (average age 53) who had suffered a heart attack. Seventeen underwent stem cell infusions while eight received standard post-heart attack care, including medication and exercise therapy. The stem … Continue reading

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Scarred Hearts Can Be Mended With Stem Cell Therapy, Study Shows

Posted: Published on February 14th, 2012

February 13, 2012, 9:47 PM EST By Ryan Flinn Feb. 14 (Bloomberg) -- Stem cells grown from patients’ own cardiac tissue can heal damage once thought to be permanent after a heart attack, according to a study that suggests the experimental approach may one day help stave off heart failure. In a trial of 25 heart-attack patients, 17 who got the stem cell treatment showed a 50 percent reduction in cardiac scar tissue compared with no improvement for the eight who received standard care. The results, from the first of three sets of clinical trials generally needed for regulatory approval, were published today in the medical journal Lancet. “The findings in this paper are encouraging,” Deepak Srivastava, director of the San Francisco-based Gladstone Institute of Cardiovascular Disease, said in an interview. “There’s a dire need for new therapies for people with heart failure, it’s still the No. 1 cause of death in men and women.” The study, by researchers from Cedars-Sinai Heart Institute in Los Angeles and Johns Hopkins University in Baltimore, tested the approach in patients who recently suffered a heart attack, with the goal that repairing the damage might help stave off failure. While patients getting the stem … Continue reading

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Drugs found in Houston's hotel room

Posted: Published on February 14th, 2012

A coroner's official says some prescription medicines were found in the hotel room where Whitney Houston died but not in large quantities. Houston was underwater and apparently unconscious when she was pulled from a Beverly Hills hotel bathtub, and she had prescription drugs in her room, officials said on Monday as the pop star's family made arrangements to fly her body home to New Jersey for a funeral at the end of the week. Authorities said that there were no indications of foul play and no obvious signs of trauma on Houston's body but that it could be weeks before the coroner's office completes toxicology tests that could establish the cause of death. The 48-year-old singer struggled for years with cocaine, marijuana and pills, and her behaviour had become erratic. Houston was found underwater on Saturday at the Beverly Hilton Hotel by a member of her staff at about 3:30pm (local time), hours before she was supposed to appear at pre-Grammy Awards gala, police Lt Mark Rosen said. She was pulled from the tub by members of her staff, and hotel security was promptly notified, Rosen said. She was pronounced dead about 30 minutes later. 'As of right now, it's … Continue reading

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Drugs found in Houston's room

Posted: Published on February 14th, 2012

A coroner's official says some prescription medicines were found in the hotel room where Whitney Houston died but not in large quantities. Houston was underwater and apparently unconscious when she was pulled from a Beverly Hills hotel bathtub, and she had prescription drugs in her room, officials said on Monday as the pop star's family made arrangements to fly her body home to New Jersey for a funeral at the end of the week. Authorities said that there were no indications of foul play and no obvious signs of trauma on Houston's body but that it could be weeks before the coroner's office completes toxicology tests that could establish the cause of death. The 48-year-old singer struggled for years with cocaine, marijuana and pills, and her behaviour had become erratic. Houston was found underwater on Saturday at the Beverly Hilton Hotel by a member of her staff at about 3:30pm (local time), hours before she was supposed to appear at pre-Grammy Awards gala, police Lt Mark Rosen said. She was pulled from the tub by members of her staff, and hotel security was promptly notified, Rosen said. She was pronounced dead about 30 minutes later. 'As of right now, it's … Continue reading

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Drugs or drowning? Science holds key to Houston death

Posted: Published on February 14th, 2012

LOS ANGELES (Reuters) - Drugs? Booze? Suicide? Drowning? Speculation on the cause of Whitney Houston's sudden death have run the gamut since the singer was found on Saturday. But don't jump to conclusions. Medical experts say it will take weeks to firmly establish the cause of Houston's death and, contrary to probes on TV crime shows like "CSI" or "Bones," sometimes science is fallible. "I suspect the popular media has made toxicology tests almost as magical as everything else," Dr. Andrew Baker, president of the National Association of Medical Examiners, told Reuters. "I am sure there are TV shows where they squirt blood into a machine and five seconds later, they get a print out of every drug the person has ever taken. (But) it just doesn't work like that," said Baker, who is also the chief medical examiner of Hennepin County, Minnesota. As in the case of Michael Jackson in 2009, or British singer Amy Winehouse last year, toxicology tests are now underway on Houston that could take up to eight weeks to yield results. Initial suspicion over Houston's death at age 48 on Saturday afternoon in a Beverly Hills hotel fell on a possible drug overdose given the … Continue reading

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Pharmacy used by Michael Jackson may have supplied Whitney Houston with pills

Posted: Published on February 14th, 2012

Whitney Houston was underwater and unconscious when staff found her in the bathtub of her Los Angeles hotel suite, police confirmed last night, amid mounting speculation about the role prescription drugs may have played in her death. The room at the Beverly Hilton hotel where the 48-year-old singer was discovered on Saturday afternoon contained several bottles of pills, they revealed. But it remains too early to speculate about whether they contributed to her demise. "She was underwater and apparently unconscious," said Lt Mark Rosen, of Beverly Hills police. "Ms Houston was pulled from the [bath] tub by members of her staff and hotel security was promptly notified." Cardio-pulmonary resuscitation was immediately performed, but it was too late to revive her and she was pronounced dead at 3.55pm. A post-mortem examination did not reveal obvious signs of trauma or foul play, but no official cause of death will be announced until toxicology tests are completed, a process likely to take between six and eight weeks. Earlier, the showbusiness website TMZ reported that a range of painkillers and sedatives, including Xanax, Ibuprofen, Amoxicillin and Midol, were recovered from the scene. Some had been obtained from the Mickey Fine clinic in Beverly Hills, … Continue reading

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Parents push autism bill clean-up

Posted: Published on February 14th, 2012

CHARLESTON, W.Va. -- Wally Aman drove from Wheeling to the state Capitol Monday to deliver a message to state lawmakers: Autistic children across West Virginia are missing out on important treatment services because of a last-minute change to the state's new autism insurance law last year. Aman's 5-year-old twins, Thomas and Joseph, aren't receiving speech and occupational therapy -- services that would help them, he said.  "The unanimous passage of the autism bill last year gave parents who have children with autism hope," Aman said. "But because of a last-minute change in the wording of the bill, we have insurance for autism therapy that won't pay for autism therapy. We just want what our children were promised." The new law allows health insurance companies to cap the amount they reimburse families for all autism services at $30,000 a year. A previous version of the legislation put a $30,000 cap on only on behavior services -- the treatment considered most effective for autism. Parents with autistic children typically spend more than $30,000 a year on "applied behavior analysis," or ABA, Aman said.  So the cap forces families to pay out of pocket heir children's speech, occupational and physical therapies, and prescription … Continue reading

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Mayo Clinic Selects Complete Genomics to Provide Outsourced Whole Genome Sequencing

Posted: Published on February 14th, 2012

MOUNTAIN VIEW, Calif., Feb. 13, 2012 (GLOBE NEWSWIRE) -- Complete Genomics Inc. (Nasdaq:GNOM - News) announced today that it has been selected by Mayo Clinic's Center for Individualized Medicine to provide outsourced whole human genome sequencing. Mayo Clinic researchers will now be able to employ Complete Genomics' sequencing service for some of its large-scale whole genome sequencing projects. The Center for Individualized Medicine operates a comprehensive sequencing laboratory in its own Medical Genome Facility, but it determined that collaboration with Complete Genomics could supplement the services available to its community of medical researchers. Under the terms of the agreement, Mayo Clinic can send genetic material to Complete Genomics for sequencing and analysis. It will continue to operate and invest in its Medical Genome Facility. Financial details of the agreement were not disclosed. "Mayo Clinic, through the Center for Individualized Medicine, already has several high-impact genome- and epigenome-based studies underway in individualized care for our patients," said Gianrico Farrugia, M.D., director of Mayo Clinic's Center for Individualized Medicine. "Access to quality whole genome sequencing services can only expedite our efforts to improve care for all of our patients with new individualized medicine tools and techniques." "It is exciting to see a … Continue reading

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Scarred Hearts Can Be Mended With Stem Cell Therapy, Study Shows

Posted: Published on February 14th, 2012

February 13, 2012, 9:47 PM EST By Ryan Flinn Feb. 14 (Bloomberg) -- Stem cells grown from patients’ own cardiac tissue can heal damage once thought to be permanent after a heart attack, according to a study that suggests the experimental approach may one day help stave off heart failure. In a trial of 25 heart-attack patients, 17 who got the stem cell treatment showed a 50 percent reduction in cardiac scar tissue compared with no improvement for the eight who received standard care. The results, from the first of three sets of clinical trials generally needed for regulatory approval, were published today in the medical journal Lancet. “The findings in this paper are encouraging,” Deepak Srivastava, director of the San Francisco-based Gladstone Institute of Cardiovascular Disease, said in an interview. “There’s a dire need for new therapies for people with heart failure, it’s still the No. 1 cause of death in men and women.” The study, by researchers from Cedars-Sinai Heart Institute in Los Angeles and Johns Hopkins University in Baltimore, tested the approach in patients who recently suffered a heart attack, with the goal that repairing the damage might help stave off failure. While patients getting the stem … Continue reading

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One mother’s quest inspired autism programs to help other families

Posted: Published on February 14th, 2012

WATERLOO — Janine Bernard didn’t want to waste any time getting help for her son while she waited for government-funded autism therapy. Two-year-old Desmond Bernard couldn’t speak, which led to tantrums because he couldn’t tell his parents what he wanted. “You have to teach them everything. Nothing comes naturally,” said the Kitchener mother. She found him specialized therapy with another mother who knows the challenges of raising an autistic child. And she returned to school to learn how to help children with developmental delays. “If you can start things really early, it makes a world of difference,” said Karen Neary, a behaviour consultant and clinical lead at blueballoon Health Services in Waterloo. Neary created new programs for parents who are worried about their child’s development, waiting for a diagnosis and services, or simply don’t know where to turn. She’s also hosting a parent group that has its first meeting on Wednesday at 6 p.m. The group, which will provide support, practical tips and a forum to share information, is open to any parent, not just clients of blueballoon. The privately run centre caters to children with physical and developmental challenges, and learning, social or behavioural problems. When Neary’s son was … Continue reading

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