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Foundation for Mitochondrial Medicine Awards Grant to Netherlands Research

Posted: Published on February 7th, 2012

ATLANTA, Feb. 7, 2012 (GLOBE NEWSWIRE) -- The Foundation for Mitochondrial Research, a US-based non-profit dedicated to funding research for the treatment of mitochondrial disease, has awarded a $50,000 grant to Professor Jan Smeitink of the Netherlands for his research involving the development of new small molecule compounds to treat mitochondrial dysfunction. The aim of Smeitink's three-year research project is to develop a novel therapy for the treatment of mitochondrial diseases, specifically targeting Leigh's disease, MELAS, LHON and Friedrich ataxia. Research shows that mitochondrial dysfunction is a central element in Autism, Parkinson's, Alzheimer's, muscular dystrophy and Lou Gehrig's disease among others. The funding by the Foundation for Mitochondrial Medicine will enable Smeitink and his research partners to use their specific and complementary expertise in developing new effective compounds to treat mitochondrial diseases. Recently, Khondrion, an offshoot company of the Radboud University Nijmegen Medical Centre (RUNMC) in The Netherlands, has identified several unique drug targets using its cell-based mitochondrial disease model developed in the past few years. In preliminary experiments, Smeitink and his research team provided proof that intervention aimed at these targets can restore or prevent the negative consequences of mitochondrial dysfunction at a cellular level. In this current research … Continue reading →

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8 Months on HRT! WHAT TO EXPECT! M to F, – Video

Posted: Published on February 7th, 2012

05-12-2010 10:01 Comment and Subscribe, TELL YOUR FRIENDS! As we all know, one possible step in transition is beginning Hormone Replacement Therapy, or HRT There are so many myths about what happens when you are on hormones. Maybe not myths so much but because There are so many different ways to prescribe hormones, you have so many different outcomes. MOST importantly, what occurs will be different for everyone! No one will react the same! So I cover the general things I have felt while being on HRT for 8 months, these are just my experiences- Not intended to diagnose or take the place of consulting a doctor. I am not going to include what I take or how I take it because I am not a doctor nor would want someone to take unsafe measures with hormones. I believe you at least need to consult a certified physician at some point when on hormones. So that you can get a recommended plan and dosage! I hope this video is helpful! PLEASE SHARE YOUR EXPERIENCES OR MAKE A VIDEO COMMENT! Send messages to http://www.youtube.com Follow me on Twitter http://www.twitter.com Originally posted here: 8 Months on HRT! WHAT TO EXPECT! M to … Continue reading →

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Susan M. Love: HRT Questioned Again — Really?

Posted: Published on February 7th, 2012

Once again we are returning to the question of whether menopausal hormone replacement therapy (HRT) increases breast cancer risk. The recent issue of Journal of Family Planning and Health Care contains an article by two researchers who argue that the data used in the previously reported Million Women Study? is too flawed to support its widely-heralded finding that HRT use increases breast cancer risk. The Million Women Study is an observational study that found that women who used estrogen and progestin had an increased risk of developing breast cancer. It is well understood that epidemiologic studies like the Million Women Study can only prove correlations, and not cause and effect. In fact, there are several observational studies that supported the use of HRT to prevent heart disease, a finding that was not born out when randomized trials were done. Moreover, the Million Women Study is not the only study to come to this conclusion, nor is it the key study that most researchers point to when talking about the risks associated with HRT. That study is the Women's Health Initiative, a randomized placebo-controlled trial that was specifically designed to measure the benefits and risks of menopausal hormone therapy -- and … Continue reading →

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2011, Kevin Eggan, How might stem cell research lead to a cure for ALS/MND? – Video

Posted: Published on February 7th, 2012

05-02-2012 17:57 Kevin Eggan, Harvard Stem Cell Institute, USA, presentation at the Ask the Experts session in Sydney on 28 November 2011. The Ask the Experts session is held each year, in association with the International ALS/MND Symposium, to give people living with MND an opportunity to hear about the latest research from experts in the field. It is organised by the host association, MND Australia in 2011, and the International Alliance of ALS/MND Associations. It is supported by the ALS Hope Foundation. Read the original post: 2011, Kevin Eggan, How might stem cell research lead to a cure for ALS/MND? - Video … Continue reading →

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Breast Cancer Genes, Risk Assessment and Screening – Lawrence Brody – Video

Posted: Published on February 7th, 2012

09-01-2012 15:30 January 6, 2012 - The Genomics in Medicine Lecture Series More: http://www.genome.gov More here: Breast Cancer Genes, Risk Assessment and Screening - Lawrence Brody - Video … Continue reading →

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Benitec Biopharma and Medistem Technologies Successfully Combined in Preclinical Stem Cell Therapy for Rheumatoid …

Posted: Published on February 7th, 2012

SYDNEY, AUSTRALIA and SAN DIEGO, CA--(Marketwire -02/06/12)- Benitec Biopharma (ASX: BLT.AX - News) and Medistem (Pinksheets: MEDS.PK - News) announced today the successful treatment of rheumatoid arthritis in preclinical models using Benitec Biopharma's patented gene silencing technology applied to stem cell-derived immune system cells called dendritic cells. The studies, which were led by Dr. Wei-Ping Min of the University of Western Ontario, were published in the "Journal of Translational Medicine" on the 31st January 2012(1). Benitec Biopharma's CEO Dr Peter French and Medistem's scientist Dr Rosalia De Nochea Champion were co-authors on the paper. "In 2003, Dr Wei-Ping Min's group, together with Medistem's CEO Dr Thomas Ichim, were the first to apply the technology of RNA Interference to the immune system, by silencing the autoimmune disease-associated gene IL-12p35(2)," said Dr. Peter French. "In the current paper, Dr. Min expanded these studies to a disease-relevant model, and using stem cell-derived dendritic cells was capable of developing promising preclinical data relevant to rheumatoid arthritis." By specifically "silencing" various genes, Benitec Biopharma's ddRNAi technology is capable of modulating stem cells outside of the body, in order to endow them with new desired therapeutic activities. The first clinical study which combined stem cell therapy … Continue reading →

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NanoMEDICINE and human upper limit – Video

Posted: Published on February 7th, 2012

02-11-2011 04:30 Read more: NanoMEDICINE and human upper limit - Video … Continue reading →

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A tool to track the intracellular trafficking of nanomedicines – Video

Posted: Published on February 7th, 2012

17-11-2011 10:03 Example of dual-color live-cell acquisition of a human RPE cell, expressing EGFP-flotillin-2 (green), 4.5 hours after exposure to DNA-polyplexes (red). The movie takes 10 minutes and is acquired at a frame rate of 2 fps, which is speeded up here fivefold to 10 fps. The field of view is 40 by 19.5 µm. Read more: http://www.nanowerk.com Visit link: A tool to track the intracellular trafficking of nanomedicines - Video … Continue reading →

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Bertrand Loubaton – Contribution of Nanomedicine to the global societal challenges – Video

Posted: Published on February 7th, 2012

05-12-2011 08:59 Bertrand, Loubaton, Contribution, Nanomedicine, global, societal, challenges, GE, Healthcare, etpn, More here: Bertrand Loubaton - Contribution of Nanomedicine to the global societal challenges - Video … Continue reading →

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Nanomedicine Panel BioEurope 2011 – Introduction by Laurent Levy – Video

Posted: Published on February 7th, 2012

13-12-2011 08:52 Nanomedicine: The Path to Personalized Medicine? Originally posted here: Nanomedicine Panel BioEurope 2011 - Introduction by Laurent Levy - Video … Continue reading →

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