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The Cambridge Centre for Myelin Repair – Video

Posted: Published on January 31st, 2012

25-10-2011 05:51 Bernard Gorman, a person with MS and member of the MS Society's Research Network, goes behind the scenes at the Cambridge Centre for Myelin Repair to find out more about their 2010 stem cell research breakthrough - the focus for a major fundraising campaign for the MS Society. Go here to see the original: The Cambridge Centre for Myelin Repair - Video … Continue reading

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MS Impacts Us All – Video

Posted: Published on January 31st, 2012

17-11-2011 17:01 Creating awareness is something each of us is committed to -- and can take action on today. By lending our individual voices, each and every one of us can lay the groundwork for the most viral MS awareness activity to date -- by simply sharing. Video transcription: It really is a small world. We are all connected. You may not know it, but you know someone with MS. Flint, Michigan: 102000 people. San Francisco, California: 805000 people. Phoenix, Arizona: 1.45 million people. People living with MS: 2.1 million people. Every hour of every day someone in the US is diagnosed with multiple sclerosis. The likelihood you know someone with MS: almost certain. You co-worker, your neighbor, your friend, your drycleaner, yourself, your partner... Someone you love and care about lives with multiple sclerosis. What is MS? Multiple sclerosis, an unpredictable, often disabling disease of the central nervous system, interrupts the flow of information within the brain, and between the brain and body. Most people are diagnosed in their 20's and 30's. But MS lasts a lifetime. There is no cure. MS is a complex disease. MS affects the central nervous system. MS is unpredictable. MS disrupts people's lives. … Continue reading

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21st Century Snake Oil, Part 1 – Video

Posted: Published on January 30th, 2012

24-09-2010 12:47 "60 Minutes" hidden cameras expose medical con men who prey on dying victims by using pitches that capitalize on the promise of stem cells to cure almost any disease. Scott Pelley reports Visit link: 21st Century Snake Oil, Part 1 - Video … Continue reading

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Cells and Gels for Tissue Engineering and Regenerative Medicine – Video

Posted: Published on January 30th, 2012

28-03-2011 15:41 Cell therapies often rely on the delivery of cells, including stem/progenitor cells, gelled together using large quantities of polymer biomaterials to heal tissue or organ defects. This lecture will explore how polymer gels can accommodate the growth of cells, including stem/progenitor cells in the regeneration of tissues and organs. Jeremy Mao, Edward V. Zegarelli Professor of Dental Medicine and Senior Associate Dean for Research in the College of Dental Medicine, Columbia University See the original post: Cells and Gels for Tissue Engineering and Regenerative Medicine - Video … Continue reading

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Hopes rise on treating spinal injuries with iPS cells transplant

Posted: Published on January 30th, 2012

Untreatable conditions can be helped with reprogrammed adult stem cells In just two years, the celebrated adult stem cell researcher Shinya Yamanaka hopes that clinical trials will begin on curing the once-untreatable spinal injuries with the help of “reprogrammed” adult cells or ‘induced pluripotent stem' (iPS) cells. Animal trials have shown promising results of transplanting iPS cells to treat paralytic spinal injury, said Professor Yamanaka, delivering a lecture on “New Era of Medicine with iPS Cells” here on Monday. The lecture was organised as part of the Cell Press-TNQ India Distinguished Lectureship Series. Prof. Yamanaka, who started his career as a physician 25 years ago and “tried to be an orthopaedic surgeon”, said: “I soon realised I was not so good at surgery. I also realised that even a good surgeon can't help many patients suffering from untreatable diseases and injuries.” This inspired him to change his career and get back to studying “basic medicine”. That's where he “met” the iPS cell, which led him to his major scientific breakthrough in 2007 allowing him to “reprogramme” adult human skin cells into embryonic-like stem cells. The iPS cells have revolutionised research on regenerative medicine: they are free from debates over ethics … Continue reading

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Stanford scientists turn skin cells into neural precusors, bypassing stem-cell stage

Posted: Published on January 30th, 2012

Public release date: 30-Jan-2012 [ | E-mail | Share ] Contact: Krista Conger kristac@stanford.edu 650-725-5371 Stanford University Medical Center STANFORD, Calif. ? Mouse skin cells can be converted directly into cells that become the three main parts of the nervous system, according to researchers at the Stanford University School of Medicine. The finding is an extension of a previous study by the same group showing that mouse and human skin cells can be directly converted into functional neurons. The multiple successes of the direct conversion method could refute the idea that pluripotency (a term that describes the ability of stem cells to become nearly any cell in the body) is necessary for a cell to transform from one cell type to another. Together, the results raise the possibility that embryonic stem cell research and another technique called "induced pluripotency" could be supplanted by a more direct way of generating specific types of cells for therapy or research. This new study, which will be published online Jan. 30 in the Proceedings of the National Academy of Sciences, is a substantial advance over the previous paper in that it transforms the skin cells into neural precursor cells, as opposed to neurons. While … Continue reading

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FDA Approves Erivedge (Vismodegib) Capsule, the First Medicine for Adults with Advanced Basal Cell Carcinoma

Posted: Published on January 30th, 2012

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)-- Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), today announced that ErivedgeTM (vismodegib) capsule was approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with a type of skin cancer, called basal cell carcinoma (BCC), that has spread to other parts of the body or that has come back after surgery or that their healthcare provider decides cannot be treated with surgery or radiation. Erivedge is the first FDA-approved medicine for people with advanced forms of the most common skin cancer. It is a capsule that is taken orally once-a-day. Basal cell carcinoma is generally considered curable if the cancer is restricted to a small area of the skin. However, in rare cases, lesions can become disfiguring and invade surrounding tissue (locally advanced) or spread to other parts of the body (metastasize). In these cases of advanced BCC, the disease cannot be effectively treated with surgery or radiation. Advanced BCC often results in severe deformity or loss of function of affected organs. “Today’s approval provides a new treatment for people with advanced basal cell carcinoma who, until now, had no approved medicines to help shrink disfiguring … Continue reading

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Fibrocell Science, Inc. Announces Recognition for LAVIV™ (azficel-T) at The 2012 Cell & Gene Therapy Forum, Washington …

Posted: Published on January 30th, 2012

EXTON, Pa.--(BUSINESS WIRE)-- Fibrocell Science, Inc. (OTCBB: FCSC.OB - News), a biotechnology company focused on the development of autologous (personalized) cell therapies for aesthetic, medical and scientific applications, announces that the June 2011 FDA approval of LAVIV™ (azficel-T) for the improvement of the appearance of “smile line” wrinkles was named the #3 top story of 2011 in cell and gene therapy and regenerative medicine at The 2012 Cell & Gene Therapy Forum in Washington, D.C. The award was voted by The Cell & Gene Therapy Forum survey responders, comprised of Director-level and above leaders in the cell and gene therapy and regenerative medicine industry. The meeting is organized annually by Phacilitate (www.phacilitate.co.uk), a specialist in the organization of exclusive events (www.phacilitate.co.uk/cgt) for leaders from the life sciences community. “We are delighted and honored that industry leaders attending The 2012 Cell & Gene Therapy Forum have recognized the FDA approval of LAVIV and we hope we continue to impress the industry with our innovations in upcoming years,” said David Pernock, Fibrocell Science Chairman and CEO. “Fibrocell Science is committed to exploring the full therapeutic potential of our personalized fibroblast cellular treatment for use in diverse medical and aesthetic applications.” About LAVIV™ … Continue reading

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Fibrocell Science, Inc. Announces Recognition for LAVIV™ (azficel-T) at The 2012 Cell & Gene Therapy Forum, Washington …

Posted: Published on January 30th, 2012

EXTON, Pa.--(BUSINESS WIRE)-- Fibrocell Science, Inc. (OTCBB: FCSC.OB - News), a biotechnology company focused on the development of autologous (personalized) cell therapies for aesthetic, medical and scientific applications, announces that the June 2011 FDA approval of LAVIV™ (azficel-T) for the improvement of the appearance of “smile line” wrinkles was named the #3 top story of 2011 in cell and gene therapy and regenerative medicine at The 2012 Cell & Gene Therapy Forum in Washington, D.C. The award was voted by The Cell & Gene Therapy Forum survey responders, comprised of Director-level and above leaders in the cell and gene therapy and regenerative medicine industry. The meeting is organized annually by Phacilitate (www.phacilitate.co.uk), a specialist in the organization of exclusive events (www.phacilitate.co.uk/cgt) for leaders from the life sciences community. “We are delighted and honored that industry leaders attending The 2012 Cell & Gene Therapy Forum have recognized the FDA approval of LAVIV and we hope we continue to impress the industry with our innovations in upcoming years,” said David Pernock, Fibrocell Science Chairman and CEO. “Fibrocell Science is committed to exploring the full therapeutic potential of our personalized fibroblast cellular treatment for use in diverse medical and aesthetic applications.” About LAVIV™ … Continue reading

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Cancer drugs affect mouse genomes for generations

Posted: Published on January 30th, 2012

Three common chemotherapy drugs cause DNA mutations not only in mice that receive treatment, but also in their offspring, according to a study published today in the Proceedings of the National Academy of Sciences USA1. The results suggest that the genome in treated mice became destabilized yielding new mutations long after exposure to the drugs has ceased. A similar phenomenon has been observed in mice exposed to radiation. Genomic damage can be seen in the offspring of mice who have received chemotherapy drugs. PAUL WOOTTON/SCIENCE PHOTO LIBRARY The work emphasizes the importance of looking at the effects of chemotherapy not only on recipients, but also on their descendants, but Yuri Dubrova, a geneticist at the University of Leicester, UK, who led the study, cautions against extrapolating the results of this study to humans. Most adults treated for cancer are either too old to have children or become sterile from the treatment. “So we’re talking about one group only: childhood cancer survivors,” says Dubrova. One recent study found no significant impact of radiation or chemotherapy on the rate of birth defects in 4,699 children of childhood cancer survivors2. Furthermore, children who are treated for cancer will not have children of their own … Continue reading

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