TORONTO - Research teams investigating a potential and hotly debated cause of MS say they are making good progress toward providing essential data that will help to design a clinical trial of a proposed treatment for the disease. The seven Canadian and U.S. teams were given $2.4 million in July 2010 to probe the connection between multiple sclerosis and a condition called chronic cerebrospinal venous insufficiency, or CCSVI, put forth as a possible cause of MS by Italian vascular surgeon Dr. Paolo Zamboni. Zamboni has theorized that MS could be caused by narrowed neck veins, which he suggests cause a backup of blood in the brain, leading to iron deposits that destroy brain cells and set off the cascade of nerve damage characteristic of MS. Multiple sclerosis is an unpredictable, often disabling disease of the central nervous system, which interrupts the flow of information within the brain and between the brain and body. Symptoms range from numbness and tingling to blindness and paralysis. An estimated 55,000 to 75,000 Canadians have the disease. “The research underway is significantly advancing our understanding of CCSVI and what its relationship might be to the MS disease process,” Dr. Tim Coetzee, chief research officer at … Continue reading
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