An international team led by scientists at Aston University in the United Kingdom may have found a new use for the old antipsychotic trifluoperazine, a conventional schizophrenia treatment. By changing the behavior of tiny protein pores in our cells called aquaporin-4 (AQP4), trifluoperazine (TFP) could stop the influx of water in the central nervous system that contributes to swelling of the brain or spinal cord after traumatic injuries or stroke, the team described in a new study published in Cell. A single dose of TFP helped injured rats recover sensory and motor functions, the researchers showed. Continue reading →

Working memory deficit one week after brain injury. The image shows the swimming path of a rat released in a water maze at the arrow trying to find a hidden platform P on first trial (sample) and a minute later (choice). The uninjured rat (sham) moves rapidly to the platform showing it remembers the location (good spatial working memory) Continue reading →

The Art Archive / Shutterstock Game of Thrones famous Mad King plot drew inspiration from numerous historical sources no doubt, from France's King Charles VI to Englands King Henry VI. Yet one famously 'mad' monarch King Ferdinand VI of Spain's illness has been diagnosed altogether differently to what historians have often argued, with a leading neurologist claiming that he suffered from brain injury, rather than a psychiatric illness. Continue reading →

Cognitive disorder implies to any type of disease, disorder or condition that harms the cognitive functioning of the person which results in improper functioning of the brain. Cognitive disorders involve memory problems and causes impairment in the functioning of brain. The major cognitive impairment disorders are delirium, dementia and amnestic disorder Continue reading →

STOCKHOLM, May 14, 2020 /PRNewswire/ -- AlzeCure Pharma AB (publ) (FN STO: ALZCUR) and Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden, have had a multi-year research collaboration in the CNS field, and their joint doctoral student Hlin Kvartsberg's solid work has now been awarded best thesis 2019 at Sahlgrenska Academy. The thesis, with the title The postsynaptic protein Neurogranin - A new item in the Alzheimer's disease biomarker toolbox, was defended at at pubic dissertation on April 12, 2019 at Sahlgrenska Academy. The thesis, which was made possible by generous support from Swedish Brain Power, focused on a new possible biomarker in Alzheimer's disease, the synapse protein neurogranin. Continue reading →

HomeOpinionChrisanne Gordon: Give special thanks to the veterans, active-duty on pandemic frontlines May is National Military Appreciation Month, since 1999 an annual opportunity for Americans to honor veterans and active-duty members of our military services. Continue reading →

Lara Spencer had never heard of On with Life until just a few years ago. She was then a Certified Nurse Assistant (CNA), about to become a Licensed Practical Nurse (LPN), when a friend told Spencer, a Kansas-native, about the skilled, long-term care facility on the southside of the Glenwood Resource Center campus. She applied soon after, was offered and accepted the job and has never once regretted her decision since. Continue reading →