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New ECG Criteria May Allow Early Detection of Hypertension-Mediated Organ Damage – The Cardiology Advisor

Posted: Published on March 6th, 2020

Electrocardiography (ECG) is a valuable tool to assess left ventricular hypertrophy (LVH), which has been associated with the development of major cardiovascular events. A set of new ECG criteria, with higher sensitivity than conventional criteria, may allow the early identification of hypertension-mediated organ damage, according to a narrative review published in the Journal of Clinical Hypertension.1 Essential hypertension is a significant risk factor for cardiovascular morbidity and mortality, and previous studies have reported increased risk for myocardial infarction, stroke, and congestive heart failure in patients with hypertension Continue reading

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PAI Health Awarded Contract to Develop and Manage Technology Platform for the Worlds Largest Exercise Study – Yahoo Finance

Posted: Published on March 6th, 2020

VANCOUVER, British Columbia, March 04, 2020 (GLOBE NEWSWIRE) -- PAI Health, a heart health software company, has been awarded the contract to develop the technology platform for the largest exercise intervention study ever performed. The study, called The Norwegian Trial of Physical Exercise after Myocardial Infarction (NorEx), will be undertaken at NTNU, the Norwegian University of Science and Technology. NorEx is a registry-based multicenter and multiregional randomized controlled trial for secondary prevention and rehabilitation of patients who have suffered myocardial infarction (MI). Continue reading

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Haptoglobin Genotype Found to Affect the Impact of Intensive Glucose-Lowering Therapy on CV Outcomes in T2DM – The Cardiology Advisor

Posted: Published on March 6th, 2020

Intensive glucose-lowering therapy was found to be associated with a reduced risk for incident coronary heart disease (CHD) and cardiovascular disease (CVD) in patients with type 2 diabetes mellitus (T2DM) and a haptoglobin (Hp) Hp2-2 genotype, but not in patients with an Hp1 genotype, according to a study published in the Journal of the American College of Cardiology. The study is a reanalysis of the Action to Control Cardiovascular Risk in Diabetes (ClinicalTrials.gov identifier: NCT00000620) double-blind 2 x 2 factorial trial, in which 5806 white adult participants from the United States and Canada (mean age, 63.16.3 years; 36% women; median T2D duration at baseline, 9 years) were enrolled Continue reading

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Molecular Inflammation and Oxidative Stress are Shared Mechanisms Involved in Both Myocardial Infarction and Periodontitis – DocWire News

Posted: Published on March 6th, 2020

BACKGROUND AND OBJECTIVE: Our aims were to improve the understanding of the pathogenic relationship between cardiovascular diseases and periodontitis and to generate new perspectives in the prevention and treatment of acutemyocardial infarction(AMI) and periodontitis. The present study evaluates possible differences in inflammation, oxidative stress, and autophagy markers among subject suffering AMI, periodontitis, or both, to explore possible common pathogenic mechanisms. Continue reading

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Association of Adoption of Transradial Access for Percutaneous Coronary Intervention in ST Elevation Myocardial Infarction with Door-to-Balloon Time -…

Posted: Published on March 6th, 2020

OBJECTIVES: We aimed to study adoption of transradial primary percutaneous coronary intervention (TR-PPCI) for ST elevationmyocardial infarction(STEMI) (radial first approach) and its association with door-to-balloon time (D2BT). TR-PPCI for STEMI is underutilized in the United States due to concerns about prolonging D2BT Continue reading

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Cardiac Biomarkers – An Essential Tool in the Diagnosis and Management of Cardiovascular Diseases: Infinium Global Research – Yahoo Finance

Posted: Published on March 6th, 2020

PUNE, India, March 4, 2020 /PRNewswire/ -- A recent report by Infinium Global Research's on the "Cardiac Biomarkers Market(Type - Myocardial Muscle Creatine Kinase (CK-MB), Troponins (T and I), Myoglobin, Brain Natriuretic Peptide (BNPs) or NT-proBNP, Ischemia Modified Albumin (IMA), and Other Types; Location of Testing - Point of Care Testing, and Laboratory Testing; Applications - Myocardial Infarction, Congestive Heart Failure, Acute Coronary Syndrome, Atherosclerosis, and Other Applications): Global Industry Analysis, Trends, Size, Share and Forecasts to 2025"estimates that the market is projected to expand with a CAGR of 12.5% over the period of 2019 to 2025 and would be worth USD 14 Billion by 2025. Continue reading

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Grindeks has successfully completed the Phase 1 Clinical Study of Its New Investigational Medicinal Product Methyl-GBB – Yahoo Finance

Posted: Published on March 6th, 2020

JSC Grindeks announces that it has completed the Phase 1 clinical study of its new investigational medicinal product metyl-GBB. This new investigational medicinal product is intended for the treatment of cardiovascular diseases. This treatment will have a unique therapeutic advantage the new medicine will be available in both parenteral and oral dosage forms. Continue reading

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Phase 2 Remyelination Trial Yields ‘Intriguing’ Interim Results – Medscape

Posted: Published on March 5th, 2020

WEST PALM BEACH, FL Among patients with relapsing multiple sclerosis (MS) and visual impairment who received a potential remyelinating treatment or placebo for as long as 36 weeks, median low-contrast letter acuity improved in the population overall, according to an interim, blinded analysis. Exploratory outcome measures of cognition, gait, and upper extremity function also improved. The results do not mean that the treatment works. Continue reading

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Increased Serum NfL Indicates Ongoing Neuroinflammation, May Predict Neurodegeneration in Early MS – Neurology Advisor

Posted: Published on March 5th, 2020

Serum neurofilament light chain (sNfL) levels are indicative of ongoing neuroinflammation and may be predictive of potential neurodegeneration in patients with early multiple sclerosis (MS), according to a study published in Multiple Sclerosis. Previous studies have depicted a strong relationship between sNfL levels and lesion burden, as well as future development of brain volume loss in patients with MS Continue reading

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Clement to be admitted into treatment following county jail release – NNY360

Posted: Published on March 5th, 2020

CANTON A Massena sex offender appeared in St. Lawrence County Court Wednesday on an order to show cause for her upcoming release to a substance abuse treatment facility. Olanta D. Continue reading

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