Skin 'may restore' diseased MS brain

8 February 2013 Last updated at 03:55 ET By James Gallagher Health and science reporter, BBC News

It may be possible to use a patient's own skin to repair the damage caused by multiple sclerosis (MS), which is currently incurable, say researchers.

Nerves struggle to communicate in MS as their insulating covering is attacked by the immune system - causing fatigue and damaging movement.

Animal tests, described in the journal Cell Stem Cell, have now used modified skin cells to repair the insulation.

Experts said there was an "urgent need" for such therapies.

Just like electrical wires, nerves have insulation - but instead of plastic, the body uses a protein called myelin.

However, diseases that result in damage to the myelin, including MS, leave the nerves exposed and electrical signals struggle to travel round the body.

A team of scientists at the University of Rochester Medical Center, in the US, used advances in stem-cell research to attempt to repair the myelin.

They took a sample of human skin cells and converted it into stem cells, which are capable of becoming any other type of cell in the body.

The next step was to transform the stem cells into immature versions of cells in the brain that produce myelin.

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Skin 'may restore' diseased MS brain