The Additional Prognostic Value of Myocardial Perfusion SPECT in Patients with Known Coronary Artery Disease with High Exercise Capacity – DocWire…

Posted: Published on December 6th, 2019

This post was added by Alex Diaz-Granados

BACKGROUND:

The prognostic value ofmyocardialperfusion imaging (MPI) in patients with known coronary artery disease (CAD) and high exercise capacity is still unknown. We sought to determine the MPI additional prognostic value over electrocardiography (ECG) stress testing alone in patients with known CAD who achieved10 metabolic equivalents (METs).

We evaluated 926 patients with known CAD referred for MPI with exercise stress. Patients were followed for a mean of 32.49.7months for the occurrence of all-cause death or nonfatalmyocardial infarction(MI). Those achieving10 METs were younger, predominantly male, and had lower prevalence of cardiovascular risk factors. Patients reaching10 METs had a lower annualized rate of hard events compared to their counterparts achieving<10 METs (1.13%/year vs 3.95%/year, P<.001). Patients who achieved10 METs with abnormal scans had a higher rate of hard events compared to those with normal scans (3.37%/year vs 0.57%/year, P=.023). Cardiac workload<10 METs and an abnormal MPI scan were independent predictors of hard events.

MPI is able to stratify patients with known CAD achieving10 METs for the occurrence of all-cause death and nonfatal MI, with incremental prognostic value over ECG stress test alone.

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The Additional Prognostic Value of Myocardial Perfusion SPECT in Patients with Known Coronary Artery Disease with High Exercise Capacity - DocWire...

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