Waqqas Afif, MD Credit: McGill University Long-term subcutaneous maintenance therapy with ustekinumab every 8 and 12 weeks can maintain clinical and endoscopic outcomes through 4 years, according to the final efficacy and safety results of the UNIFI long-term extension study in patients with ulcerative colitis (UC). In patients who responded to intravenous ustekinumab induction, therapy was safe and effective at maintaining symptomatic remission, providing clinical and endoscopic benefit to patients through 4 years of treatment without the need for concomitant corticosteroids and with no new safety signals reported.1 Due to the life-long nature of UC, long-term treatment is often required to induce and maintain remission Continue reading
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