What Is Parkinson's Disease? Parkinson's disease is a fairly common age-related and progressive disease of brain cells (brain disorder) that affect movement, loss of muscle control, and balance. Usually, the first symptoms include a tremor (hand, foot, or leg), also termed a "shaking palsy." The majority of people develop Parkinson's disease after age 60 (although a few patients like Michael J. Fox develop it at an early age of about 30 and boxer Muhammad Ali at age 42). Men are about 1.5 times more likely to develop it than women. In general, the disease slowly progresses with more pronounced symptoms developing over many years. Although a few patients, especially those who develop it in their younger years may have more rapid symptom development, symptoms slowly increase over many years. Treatments may reduce symptoms in many patients. Three key symptoms that develop early in Parkinson's disease are a tremor, usually on one side of the body (hand, foot, arm, or other body part) when the person is at rest. The second symptom is rigidity, or resistance to movement when someone tries to move the person's joint or when the person has difficulty going from a sitting to a standing position. The … Continue reading
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